Tag Archives: Rebecca Riley

Bad Side-Effects Ahead For Pharma?

In 2006, The New York Review of Books reported that four-year-old Rebecca Riley died of the effects of two prescription drugs—Clonidine and Depakote.

These medications, along with Seroquel, were prescribed for Rebecca after she was diagnosed, at the age of two, with attention deficit hyperactivity disorder (ADHD) and bipolar disorder. The three drugs are not approved by the Food and Drug Administration (FDA) for treatment of ADHD or long-term treatment of bipolar disorder, nor are they approved for children as young as Rebecca.

The New York Review of Books‘ recent two-part article (1) by Marcia Angell on the treatment of mental illness with psychoactive drugs (those that affect the mental state) addresses an issue that may one day prove very important to investors in pharmaceutical stocks. (All statistics and quotations herein are drawn from Dr. Angell’s article.) It is not illegal for a doctor to prescribe a drug off-label, that is, for a non-FDA-approved use, but a drug marketer cannot lawfully encourage a doctor to do so. The profits in psychoactive drugs, however, make it tempting to flout the law. In the past four years, AstraZeneca (AZN), Pfizer (PFE), Eli Lilly (LLY), Bristol-Myers Squibb (BMY) and Forest Labs (FRX) have all settled federal charges of marketing psychoactive drugs off-label, at a cost running into hundreds of millions.

“Drugging Pre-School Children: A crime against childhood—children as young as 2 prescribed powerful anti-psychotics”

In 2001, Harry Markopolos repeatedly warned the authorities about Bernie Madoff. No one listened. Only a serious downturn in the economy led to Madoff’s downfall. It’s not a Ponzi scheme, but once again, no one is listening and the red flags are everywhere. This time the victims are our very young, innocent children in the millions. Today, children as young as 2, are being prescribed powerful anti-psychotic medications. Side effects include tics, drooling, and incessant eating. Some children have gained up to 100 pounds and often progress to becoming diabetic.

The Portland Press Herald: Psychiatric Drugging of American Children is Cause for Alarm

The use of powerful drugs to treat younger and younger patients has gone far beyond disturbing. The age of children being medicated with prescription psychiatric drugs is getting younger and more widespread every year. According to a 2010 study of data on more than a million children reported by American Academy of Child and Adolescent Psychiatry’s journal, the use of powerful anti-psychotics with privately insured U.S. children, ages 2 through 5, doubled between 1999 and 2007.

Wholesale sedation of young children medically, morally indefensible

The twin murder trials of the parents of Rebecca Riley, who died at age 4 of an overdose of the psychiatric drug, clonidine, have cast a spotlight on the beliefs and practices of the doctor who prescribed the drug. Kayoko Kifuji was granted immunity in both trials in exchange for her cooperation for testifying. Reactions from jurors, comments online and letters to the editor based on newspaper accounts of Kifuji’s testimony range from confusion, shock, and outrage directed at the doctor’s role in the tragedy.