Tag Archives: antidepressants

False peace of mind – Antidepressant Placebos

Beginning in 1998, a series of studies have repeatedly questioned the difference in efficacies between antidepressant drugs and placebos. Pioneering analysis work done by University of Connecticut researchers Irving Kirsch and Guy Sapirstein confirmed the effectiveness of antidepressants – but also their inert counterparts. In 38 studies conducted with over 3,000 depressed patients, placebos improved symptoms 75 per cent as much as legitimate medications.

“We wondered, what’s going on?” said Kirsch in a 2010 interview with Newsweek. The medical community, skeptical of his analysis, asked him to instigate a more comprehensive study with the results of all clinical trials conducted by antidepressant manufacturers, including those unpublished – 47 studies in total.

Over half of the studies showed no significant difference in the depression-alleviating effects of a medicated versus non-medicated pill. With this more thorough analysis, which now included strategically unpublished studies from pharmaceutical companies, placebos were shown to improve symptoms 82 per cent as much as the real pill.

Billion Dollar Drug Company Law Firm Restructures Connecticut Welfare System

A mother-turned advocate’s journey that links a non-profit children’s advocacy group, with assets over $15 million [2009] with nationally-renowned mass tort and class action defense law firms, to the Connecticut DCF – an $865 million bureaucracy, as described by the Connecticut Mirror.

A sugared pill

When Daniel Carlat, a psychiatrist in Massachusetts, was flown to New York with his wife by Wyeth, the “training” weekend he attended in a luxury hotel was topped off with a Broadway show. It was early 2001 and he had just agreed to the US pharmaceuticals company’s proposal that he give talks to doctors about its antidepressant Effexor. During the following year, he was regularly paid fees of $750 a time to drive to “lunch and learn” sessions where he would speak for 10 minutes to emphasise the drug’s advantages to fellow doctors, using slides prepared by the company. “It seemed like a win-win,” he recalls. “I was prescribing it, educating doctors and making some money.” But within a few months, he became disillusioned with his co-option as a marketing representative. He was selectively presenting clinical data that put the drug in a positive light to physicians who had been targeted by the company through “data mining” techniques that identified their individual prescription patterns.Dr Carlat has spoken out as part of a growing backlash against such aggressive marketing tactics, which are leading to significant changes in the relationship between doctors and drug companies. But even as pharmaceuticals executives argue that such problems belong to the past and were always exaggerated, they are bracing for both intensifying penalties and calls for further reform.

Antidepressants/Pain Relievers Cause “unprecedented number of emergency room visits & deaths”

Approximately 700,000 visits to the emergency room were linked to drug-related poisoning in 2007, according to a new study published February 28 on the Nationwide Children’s Hospital website. Researchers found that 44 percent of poisonings were caused by prescription medications such antidepressants and opioid pain relievers.

The study found that, on average, 1,900 people per day were sent to the emergency room due to drug overdoses. According to researchers at the Center for Injury Research and Policy of the Research Institute at Nationwide Children’s Hospital, the cost associated with these visits totals approximately $1.4 billion per year.

Dangerous doctors slipping through the cracks

It took the discovery of guns and grenades to suspend the license of a psychiatrist who some say should have come under scrutiny years earlier. One night a Crestwood police sergeant doing a routine building check noticed an open door to the office of psychiatrist Joel Carroll. Stepping inside the cluttered office, he discovered roaming cats, a Colt AR-15 assault rifle and other guns, ammunition, military-grade smoke grenades, sex toys, and pornography. “Well, for the lack of better terminology, we considered it a pigsty,” Sgt. Thomas Kaniewski testified about his April 2009 discovery. “It looked in complete disarray. We couldn’t believe that someone could actually conduct business in an office like that because of the conditions it was in.”