Tag Archives: violence

PEOPLE’S PHARMACY:Can drugs cause violent behavior?

Americans revere personal responsibility. It resonates with our respect for accountability and frontier justice. That may explain why we have a hard time believing that medications could alter people’s personalities or lead them to behave badly. Violence as a drug side effect seems preposterous to patients, pharmacists, physicians and even juries. Trying to use the “Prozac defense” to justify killing or hurting someone is often met with scorn..

Antidepressant prescribing information, for example, warns physicians that, “All patients being treated with antidepressants for any indication should be monitored appropriately and observed closely for clinical worsening, suicidality, and unusual changes in behavior.” Drugs such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil) and sertraline (Zoloft) carry warnings about aggressiveness, agitation, hostility, impulsivity and irritability.

The stop-smoking medication varenicline (Chantix) also comes with warnings about agitation, hostility, depressed mood and changes in behavior. The trouble with such warnings is that people don’t imagine that these bad things could happen to them.

Autopsy of Florida School Board Shooter Shows Antidepressant in His System

ANAMA CITY — The man who held the Bay District School Board hostage before killing himself last year had an antidepressant, acetaminophen and foot fungus medication in his system, his autopsy revealed.

The report on Clay Duke was released Wednesday by the Bay County medical examiner’s office.

Duke, 56, killed himself Dec. 14 after firing several shots at school board members during a public meeting. Duke was brought down by three bullets from Mike Jones, the district’s chief of safety.

A toxicology report revealed that at the time of Duke’s death, he had atropine, a drug commonly used in emergency rooms to resuscitate dying patients; acetaminophen; Terbinafine, used to fight fungal infections in fingers and toes; and Citalopram, an antidepressant found in Celexa, in his system.

Forest Laboratories Inc., which makes Celexa, notes on its website the company urges patients to “call a health care provider right away if you or your family member has any of the following symptoms, especially if they are new, worse, or worry you: thoughts about suicide or dying, attempts to commit suicide, new or worse depression, new or worse anxiety, feeling very agitated or restless, panic attacks, trouble sleeping (insomnia), new or worse irritability, acting aggressive, being angry, or violent, acting on dangerous impulses, an extreme increase in activity and talking (mania), other unusual changes in behavior or mood.”

Panel to Examine Murder and Suicide Associated With Antidepressants

On Saturday morning April 9th of this year, a panel discussion will be held for the public and professionals on the theme of “Psychiatric Drug Tragedies: Personal, Legal and Medical Perspectives.” The two-hour presentation focuses on suicide and murder potentially caused by antidepressant medications. It is part of the international Empathic Therapy Conference put on by the Center for the Study of Empathic Therapy, Education & Living (April 8-10, 2011 in Syracuse, New York).
A great deal is now known about suicide and violence in association with the newer antidepressants such as Prozac (fluoxetine), Paxil (paroxetine), Zoloft (sertraline), Luvox (fluvoxamine), Celexa (escitalopram), Lexapro (escitalopram), Cymbalta (duloxetine), Effexor (venlavaxine), Pristiq desvenlafaxine), and Wellbutrin (bupropion).

Psychiatric News — Antidepressants/Antismoking Drugs Linked to Violent Behavior

A link between several types of psychotropic medications and violent behavior toward others has been documented in a recent study.

The medications most strongly linked to violent behavior were the smoking-cessation aid varenicline and antidepressants, regardless of class.In a study published in the December 15, 2010, PloS One, the researchers used 2004 to 2009 data from the Food and Drug Administration (FDA) Adverse Event Reporting System. They found that during the study period, 780,169 serious adverse events of one kind or another had been reported for 484 drugs, and that of those serious adverse events, 1,937 had been acts of violence. They defined a violent event as any case report containing one or more of the following items: homicide, physical assault, physical abuse, homicidal ideation, or violence-related symptom, but not more ambiguous descriptions such as crime, aggression, belligerence, or hostility.

Finally—An Official Admission: Psychiatric Drugs Cause Violent & Homicidal Behavior

TIME MAGAZINE—When people consider the connections between drugs and violence, what typically comes to mind are illegal drugs like crack cocaine. However, certain medications — most notably, some antidepressants like Prozac — have also been linked to increase risk for violent, even homicidal behavior.

A new study from the Institute for Safe Medication Practices published in the journal PloS One and based on data from the FDA’s Adverse Event Reporting System has identified 31 drugs that are disproportionately linked with reports of violent behavior towards others…