Posts Tagged ‘withdrawal’

Addiction Specialist Says It’s Easier to Withdraw Patients from Heroin than from Xanax

Monday, November 14th, 2011

KNTV – November 14, 2011

"It's so much easier to take people off heroin. I'd rather take 100 people off heroin than one person of Xanax because I know they'll have a year of withdrawal," says addiction specialist Dr. Jerry Callaway.

Also known as Alprazolam, it’s the 11th most prescribed drug in the United States, but you often don’t need a doctor to get it.

22-year-old “Nick” is a recovering Xanax addict.

In addition to getting them at parties, he says he also would get prescriptions for hundreds of Xanax pills from doctors.

“All you have to do is walk into a doctor’s office and say you have anxiety, at least that’s what I did and it was written to me,” he says.

Nick says he knew he had to kick the drug when he took Xanax, blacked out while driving and seriously injured three people.

“It’s sobering to know my actions caused innocent people great bodily injury,” he now says.

Doctors warn weaning off the drug has serious risks too.

“It’s so much easier to take people off heroin. I’d rather take 100 people off heroin than one person of Xanax because I know they’ll have a year of withdrawal,” says addiction specialist Dr. Jerry Callaway.

A spokeswoman for Pfizer, the manufacturer of Xanax says, “When prescribed and taken as indicated Xanax has a well established safety profile and is an important treatment option that has benefitted millions of patients.”

Between 2004 and 2008 the Centers for Disease Control reported an 89 percent increase in the number of emergency room visits nationwide related to the non-medical use of Xanax and other drugs in its class.

According to drug site which reviews the FDA’s adverse events data base, people using Xanax reported more than 11,000 adverse events between 2004 and march of this year.

They include 83 deaths, 107 completed suicides and 100 comas.

Addiction experts also say you might be surprised whose abusing Xanax.

“It might be a stay-at-home mom or a working mom, and in an attempt deal with the overwhelm of that they go to the doctor, they talk to them about the anxiety, they talk about the overwhelm the doctor prescribes them Xanax and next thing you know now they’re addicted to it,” says treatment center director Lori Johnson.

The FDA does require a warning to patients that Xanax can become addictive, but there is a petition asking them to add a stronger and more visible safety alert.

“I think it’s overdue,” Dr. Callaway says.

Nick, who has now gone six months without Xanax, has a warning of his own for those considering experimenting with the drug.

“At all costs stay away from it. There’s nothing good about it, nothing good can come out of Xanax,” he says.

http://www.ksdk.com/news/article/285646/9/Xanax-building-dangerous-reputation

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FDA Issues Label Changes for Antipsychotic Drugs—Outlining risks for newborns whose mothers took drug

Wednesday, February 23rd, 2011

ModernMedicine – Feb 22, 2011

TUESDAY, Feb. 22 (HealthDay News) — The U.S. Food and Drug Administration has notified health care providers that the Pregnancy section of drug labels for the entire class of antipsychotic drugs has been updated. The new drug labels include additional and consistent information regarding the potential risk for abnormal muscle movements (extrapyramidal signs [EPS]) and withdrawal symptoms among newborns whose mothers received the drugs in the third trimester of pregnancy.

The drug labels were updated based on information from the FDA’s Adverse Event Reporting System database, which revealed 69 cases of neonatal EPS or withdrawal with all antipsychotic drugs. Most cases were attributable to multiple factors, but some neonatal EPS and withdrawal cases may have occurred due to antipsychotics alone.

The symptoms of EPS and withdrawal in infants include agitation, abnormally increased or decreased muscle tone, tremor, sleepiness, severe difficulty breathing, and difficulty in feeding. Symptoms may subside in a few hours or days and may not require treatment, but some newborns may require longer hospitalizations.

According to the FDA, “health care professionals should be aware of the effects of antipsychotic medications on newborns when the medications are used during pregnancy. Patients should not stop taking these medications if they become pregnant without talking to their health care professional, as abruptly stopping antipsychotic medications can cause significant complications for treatment.”

http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/FDA-Issues-Label-Changes-for-Antipsychotic-Drug-Cl/ArticleNewsFeed/Article/detail/708731?contextCategoryId=40130

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Will we ever wake up to the deadly risks of happy pills?

Tuesday, December 14th, 2010
The Daily Mail, December 13, 2010
by John Nash

As new research reveals antidepressants raise the danger of heart attacks, the disturbing cost of this modern addiction

Just as David Cameron launches his campaign to boost national happiness, along comes grim news for the 12 million Britons taking happy pills. London-based researchers have just announced that antidepressants raise the risk of fatal heart attacks.

This research is only the latest wake-up call for a nation hooked on happy pills. Might we finally heed the warnings and shake ­ourselves out of our pharmaceutical stupor?

It is high time we did: a small mountain of studies shows that antidepressant drugs are largely ineffective. But more than that, they can ruin lives by creating chronic dependency and a grinding ­hopelessness that ­sometimes leads to self-neglect and death.

The latest study, by Dr Mark Hamer, a ­public health researcher at University ­College ­London, shows that people on the older drugs — tricyclic antidepressants — are at far higher risk of cardiovascular disease than those ­taking the newer class of pills, selective ­serotonin reuptake inhibitors (SSRIs).

But if I were taking SSRIs, I would not be cheered by the findings. Tricyclics were ­discovered in the Forties and it is only now we have identified these dangerous effects.

Moreover, some SSRI drugs are known to cause serious problems such as stomach bleeding. In addition, the withdrawal ­symptoms can be so severe that patients may become dependent on them.

Dr Hamer says his findings do not only affect people with depression, because antidepressants are also prescribed to people with back pain, headache, anxiety and sleeping problems.

Last year, according to Dr ­Hamer’s ­figures, about 33 million antidepressant prescriptions were dispensed in England.

At some point, surely, there will be no one left to prescribe for. In my view, it’s fast becoming one of the greatest medical scandals of our age.

The most worrying thing about these drugs is not their side-effects, but their widespread non-effect: they just don’t work for most ­people with mild to moderate depression.

Two years ago, researchers at Hull ­University concluded that the pills only benefit ­people who are most seriously, clinically depressed. In these extreme cases, there is often a physical problem in their brain, a result of genetics or accident. But what of the rest?

There is a growing view that many people are being needlessly drugged because the natural state of feeling unhappy is viewed as an illness, rather than a ­normal part of life that we should experience and learn from.

An American study of 8,000 ­people who had been treated for depression found that a quarter of them were not clinically sick, but had just undergone a normal life event such as bereavement.

Their symptoms, it said, should be left to pass naturally (that, of course, would be a blow to the drug manufacturers, who profit so handsomely from the mass ­consumption of their mind-numbing chemicals).  For most of us, the healthiest option is to face our problems, rather than disappear down a black hole of antidepressant dependency.

One leading expert, Randolph Nesse, a psychiatry professor at Michigan University, argues that this mild form of depression is ­beneficial, often ­interjecting in life to tell us to stop what we are doing and reconsider.

This can help, he says, when something awful happens to us, such as a job loss or relationship break-up, when it makes sense to slow down to grieve, reassess and make changes.

But instead, we live in a world that tells us that when we feel out of sorts we need a pill to recover.

It is this belief that ­creates queues of patients at the doors of hard-pressed GPs, who often feel they have no option but to hand out happy pills as though they were sweeties.

Many patients later claim they couldn’t have coped without them. They will swear that ‘the drugs make me feel better, so they must be working’. But often the drugs do not actually work as chemicals. Instead, they merely reassure us — the so-called placebo effect.

In 2008, Professor Irving Kirsch at Hull University found something strange when he took a close look at some figures from drug manufacturers’ own trials of four common antidepressants.

The drugs improved patients’ sense of wellbeing. So far, so ­unremarkable.

But many of those involved in the trials were given sugar pills instead of antidepressants.

And their depression scores improved just as much as those on the real pharmaceuticals. In other words, the placebo patients put so much store by the magical (and much-promoted) power of antidepressants that they lifted their own morale without any genuine chemical intervention. Such is the life-enhancing power of human belief.

Everybody hurts: Sadness is a part of life and shouldn’t always be treated as an illness

But this phenomenon also has a dark side: the opposite of placebo, which is called the ‘nocebo’ effect.

This occurs when you convince someone that a particular thing will do them harm, and they begin to feel sick.

Talk to someone about food poisoning while they are tucking into a hearty meal and you will see the nocebo effect at work.

Sadness is a part of life and shouldn't always be treated as an illness

Something similar is happening in our pill-obsessed world. When we are convinced that we need drugs to get us out of an ­emotional crisis, we stop doing things to help ourselves.

This was clear from the latest research. Dr Hamer found that tricyclic drugs raise a person’s heart attack risk.

But that risk was dwarfed by another danger: the people ­taking the drugs often lost the will to look after themselves properly. They were more likely to smoke, be overweight and not exercise.

Dr Hamer says that if they started living more healthily they would cut their heart attack risk by three times. Exercise and weight loss would also help alleviate their depression and anxiety.

But people stuck in the role of helpless drug-munchers often ­cannot make that change for themselves.

They simply sit waiting for their questionable pills to work. And when the pills fail, they become even more demoralised. It’s a vicious cycle, and one that’s ­sucking in more and more vulnerable people.

Read more: http://www.dailymail.co.uk/health/article-1338340/Will-wake-deadly-risks-happy-pills.html#ixzz186xwdATE

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Glaxo Failed to Warn About Paxil Risks, Lawyer Says at Philadelphia Trial

Tuesday, November 9th, 2010

Note from CCHR: Also see attorney Karen Barth Menzies interview on Paxil withdrawal effects and documents withheld from the public http://www.youtube.com/cchrint#p/c/B9EA75455D155D89/3/Mpex0n0DXuc

Bloomberg News

by Jeff Feeley, November 9, 2010

GlaxoSmithKline Plc,  the U.K.’s largest drugmaker, failed to properly warn consumers that its antidepressant drug Paxil could cause birth defects, a lawyer for the family of an injured teenager told jurors.

Glaxo officials had research from the 1980s showing Paxil caused deaths among the offspring of animal test subjects and didn’t provide clear warnings about those deaths, Kimberly Baden, a lawyer for Anna Blyth and her family, told a Philadelphia jury. Baden said the drug caused a narrowing of the aorta leading from the heart of Anna, now 14 years old.

“We believe the evidence will show Paxil caused Anna’s birth defects,” Baden said in opening statements in the trial. “We believe the warnings and instructions put out in 1995 weren’t appropriate and reasonable.”

The Blyth family’s case is the first over Paxil’s birth- defect risks to go to trial since the company agreed in July to pay more than $1 billion to settle 800 cases alleging the company failed to adequately warn consumers and their doctors about the drug’s hazards. The Blyth case wasn’t part of the settlement.

In the first Philadelphia trial, a jury ordered Glaxo in October 2009 to pay $2.5 million to the family of a 3-year-old boy born with heart defects his mother blamed on the drug.

$11.7 Billion in Sales

Glaxo officials contend Paxil played no role in Anna’s heart defects. They were most likely caused by genetics or the fact that her mother became pregnant late in life, Chilton Varner, a lawyer for the drugmaker, told jurors in her opening statement.

The deaths of Paxil animal test subjects had nothing “to do with Anna Blyth’s heart defects,” Varner said.

Approved in 1992 for U.S. use, Paxil generated about $793 million in sales in 2009, or about 1.8 percent of Glaxo’s total revenue. The company had $11.7 billion in U.S. Paxil sales over nine years starting in 1997, according to documents made public last year in a Pennsylvania trial over birth-defect claims.

Chief Executive Officer Andrew Witty has moved to replace revenue lost to generic versions of drugs such as Paxil. The drugmaker said in May it plans to double revenue from India and China by 2015 as it cuts prices to match competitors in emerging markets.

The company has paid out more than $2 billion to resolve a wave of litigation over Paxil, including claims the anti- depressant caused suicides in some users and withdrawal symptoms. In July, Glaxo set aside $2.4 billion to resolve litigation over Paxil and its Avandia diabetes drug.

Second Wave

After announcing its settlement of Paxil suits this summer, the company faced a second wave of suits over the drugs, said Carl Tobias, a University of Richmond law professor who teaches classes about mass-tort cases. That’s not unusual once a big- dollar settlement is on the table, he said.

“You’ll have plaintiffs lawyers who hope to get in on a settlement by going out and finding some new cases,” Tobias said. “Glaxo probably feels it had to litigate this case to send a signal that it’s not going to settle every one of these birth-defect cases, especially if they are weak.”

Sarah Alspach, a Glaxo spokeswoman, didn’t immediately return a call for comment on how many Paxil birth-defect cases remain outstanding.

In Anna’s case, the Summerville, South Carolina, resident had to undergo two rounds of open-heart surgery within nine months of her birth, Baden told jurors.

Her mother, Marsha Blyth, had taken Paxil for a short time during her pregnancy to deal with depression, Baden noted.

Glaxo’s Paxil warning label didn’t make it clear that offspring from animals on which the drug had been tested died, she said.

Read the rest of the article here: http://www.bloomberg.com/news/2010-11-09/glaxo-failed-to-warn-about-paxil-risks-lawyer-says-at-philadelphia-trial.html

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I lost ten years of my life as a middle class, NHS sponsored drug addict…

Monday, October 11th, 2010

( NHS—National Health Services)

The Daily Mail, UK

By Philip Robinson
October 12,  2010

Philip Robinson was 25 when he went to his GP with mild depression. The pills he was prescribed changed his life, turning him into a ‘zombie-like’ addict — just one of the 1.5 ­million Britons whose lives have been ruined by prescription drugs. Here, with extraordinary candour, he reveals how he battled to get his life back.

The problem began when I got married. ­Uncertain about the commitment I had just made and torn between wanting to leave my wife and not wanting to hurt her, I started to drink.

I wasn’t desperately depressed, nor was I drinking myself to oblivion. In fact, compared with my fellow journalists on the lads’ magazine Loaded, where I worked at the time, my drinking wasn’t a problem; I was just going through a low point.

It was 1998. I was 25 years old, and had been married for just a year when I went for the doctor’s appointment that would drive me to the edge of insanity and rob me of the next ten years of my life.

Back from the brink: Philip with wife Anna and their children

Back from the brink: Philip with wife Anna and their children. He became hooked on tranquillisers prescribed to beat mild depression

I was told, in the nicest ­possible way, that I was a depressed ­alcoholic. I was so shocked I gave up drinking immediately. I have not touched a drop since.

Then the doctor prescribed 90 Valium pills and a bottle of beta blockers to help with stress, and recommended I visit a psychiatrist in Harley Street.

I can still remember looking at the bottle in disbelief. I’d seen people thrown out of nightclubs for possessing two of these pills. The doctor had just given me 90!

What I didn’t realise at the time was that antidepressants and tranquillisers create long-term users. Thanks to the pills that my doctor had just handed over like Smarties, I was already on the road to what is known as ‘involuntary tranquilliser addiction’.

Put simply, this is where people seeking short-term help for ­anxiety end up hooked on ­powerful mood-altering drugs, sometimes for life. I had just been turned into a middle-class, NHS-­sponsored junkie, one of the 1.5 million Britons addicted to prescribed medication.

It comes at a price for the NHS, too: the health service spends £3 billion a year on tranquillisers and antidepressants alone.

Even back then I was shocked to be given so many drugs by the NHS. I remember one colleague noting the number of pills I was packing away in the course of day and telling me to take half. But, as far as I was ­concerned, I’d obtained these drugs from the doctor, and ­doctor knows best.

In Harley Street I was given my first supply of anti-­depressants and told that I was simply ­suffering from anxiety and depression.

After a few months I was no better. In fact, I was miserable, and seemed to be experiencing new nervous symptoms. In hindsight I was probably suffering side-effects from the drugs.

‘My wife became accustomed to my ever-changing personality, which altered according to whichever pills were being tried out on me by my ­psychiatrist’

Over the next few years, Anna, my wife, became accustomed to my ever-changing personality, which altered according to whichever pills and dosages were being tried out on me by my ­psychiatrist in Harley Street.

Despite the side-effects, Anna and I both trusted the doctors and I tested a host of antidepressants and mood-altering pills, trying to find the right combination that would cure my depression and give me back my life.

I remember these pills mostly for their side-effects. In one instance, I was offered a choice of two pills: one would make me fat, the other would give me a sexual dysfunction. I chose the weight gain.

Another course of pills made me vomit violently if I took them on an empty stomach.

Feeling increasingly depressed, dislocated, and paranoid, I was starting to lose sight of who I was. I began to display the symptoms of someone who was genuinely mentally ill and I took to ­sleeping all day, unable to get out of bed.

I left full-time work to recover at home and retreated from all but two or three of my friends. Anna loyally stood by me, even though I was growing more angry, depressed and unstable.

I had also become hooked on Valium. If I ran out of pills and the doctors’ surgery was closed, I would go to the hospital for an emergency prescription or face cold turkey.

Unlike illegal drugs, pres­cription drugs are incredibly convenient. You can unscrew the lid while walking for the bus, take a couple of neatly pressed, official-looking pills — medicine — and slip into a metaphorical side room. Tranquilliser users watch life though a chink in a pharmaceutical ­curtain, unable to participate in their own existence.

Philip in the grip of addiction when son Oscar was aged one: He struggled to cope with the pressures of marriage and fatherhood but his prescribed medication was more curse than cure

Philip in the grip of addiction when son Oscar was aged one: He struggled to cope with the pressures of marriage and fatherhood but his prescribed medication was more curse than cure

Five years after my first ­prescription, it seemed there wasn’t an antidepressant in the world that worked on my brain, yet my Harley Street doctor seemed determined that there was a pharmaceutical answer to my problem.

I was depressed, but Anna and I did have some moments of ­happiness and normality. We had moved into a new house and Anna was pregnant with our first child. I felt that this was my side of the arrangement, my duty, and that I owed her a child.

I loved her, but I was pretending to be a normal dutiful caring husband when, in reality, I was little more than a waxwork.

My state worsened when I was put on a powerful (and expensive) anti-epileptic drug called Depakote. Depakote is so toxic that it requires a blood test to be taken first.

I am not epileptic, but the pill is commonly given to severely ill ­people who are bipolar. As far as I knew, I had not been diagnosed with either illness.

‘I’d gone to my doctor initially to seek help because I was a young man, overwhelmed by the responsibility of marriage. At what point did I acquire severe mental health issues?’

I got my blood tests done and took Depakote alongside Effexor (an antidepressant), Valium (a tranquilliser) and Zopiclone (a sleeping pill). All I required was a pair of baggy trousers and green face paint and I could have ­doubled up as a zombie.

I found myself unable to laugh, or smile, or cry. I was taking more and more Valium to cope with mood swings related to ­taking ­Valium. I was by now taking double or triple my original ­prescribed dose.

An additional problem was that heavy doses of tranquillisers slow your breathing and suppress your gag reflex.

One night, after approximately 70mgs and some sleeping pills, I woke up aware that I was about to swallow my tongue, which had lolled back into my throat, almost creating an airtight seal. Fortunately, I had enough air in my lungs to cough it out. I remember not feeling concerned at the time.

As the Depakote established itself in my brain, I became cold and detached. I had ‘decided’ to live nocturnally, as this was optimum for my writing. I wanted peace and quiet. I avoided my young family, content with silence and the sound of blood pulsing in my ears.

After a few months of this weird, living death I was incapable of understanding or empathising with other peoples’ emotions. None of it seemed relevant.

The tipping point came when I visited my GP to speak about my continuing prescriptions. She clicked through my records on her screen and casually noted that I should continue my medication because I was listed as being on my local council’s Severe Mental Health Register.

Severe Mental Health Register? I left the appointment consumed by a sense of tragedy.

I’d gone to my doctor initially to seek help because I was a young man, overwhelmed and confused by the responsibility of marriage. At what point did I acquire severe mental health issues?

When did I become a threat to myself and others? I’m a threat to an open packet of chocolate biscuits, but not much else. I had found rock bottom.

Deep down, I knew that I couldn’t be bipolar and I had not been diagnosed as such. I was a happy child from a lovely family. My upbringing was so great that when I described it to psychologists, they seemed to be convinced I was making it up to conceal my inner torment.

I realised the only way to find out who I really was would be to get my brain chemistry back to how it was when I could last remember feeling normal. Back to before I ever saw a doctor or even had a drink.

I needed to be a kid again. I went back to see the doctor a ­couple of weeks later and told her that I had made the decision to come off the pills.

She wasn’t so sure and warned that my mental health might well collapse if I stopped taking the drugs and that there was a risk of hospitalisation. I wasn’t offered any help or advice.

Despite this prophecy of doom hanging over me, I found dropping the ­bipolar pills to be a slow, but relatively easy process. About a month after I stopped taking them, the world seemed brighter and I started to write again and feel alive.

I filled up notepads with ideas, and Anna noticed that I was more engaged with life, she could see my old self coming back.

A couple of months later, only ­Valium remained. I had now been on these mood-altering tranquillisers for ten years and lowering the dose was an agonising battle. Each milligram I took out of my bloodstream was paid for by huge ebbs and flows in my sanity levels.

Over the next two years, I threw myself into bout after bout of ­Valium withdrawal, lowering the dose each time and enduring what felt like a three month-long Mad Hatter’s tea party in my head.

Read the rest of this article here: http://www.dailymail.co.uk/health/article-1319716/I-lost-years-life-middle-class-NHS-sponsored-drug-addict-.html?ito=feeds-newsxml

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Doctor: Paxil “Especially Notorious” for Causing Withdrawal

Monday, October 11th, 2010

Note from CCHR: To see the 42 international warnings/studies on Paxil visit our psychiatric drug side effects search engine http://www.cchrint.org/psychdrugdangers/drug_warnings.php or watch this video on Paxil causing addiction/withdrawal featuring attorney Karen Barth Menzies http://www.youtube.com/watch?v=Mpex0n0DXuc

Lawyers and Settlements

October 9, 2010

Atlanta, GA: There are a number of Paxil side effects associated with the antidepressant, and some patients continue to experience these effects even after discontinuing use of the drug.

Doctor: Paxil "Especially Notorious" for Causing WithdrawalDr. Charles Raison, an associate professor at Emory University, wrote in response to a reader’s question on CNN that about 20 percent of patients experience withdrawal symptoms when they stop taking antidepressants.

Raison says that the common symptoms of antidepressant withdrawal include dizziness, anxiety, sensory disturbances and flu-like symptoms.

According to Raison, coming off the medication slowly is important.

“The trick to lowering your chances of having these symptoms is to reduce the dose of the antidepressant as slowly as possible,” he writes. “For people who are really sensitive it can take months to get off an antidepressant slowly enough to avoid withdrawal symptoms.”

Raison also said that Paxil is “especially notorious for causing withdrawal problems” because of its short half-life in the body.

Paxil is also associated with a number of side effects for those currently taking the medication, including birth defects and depression.

Read the rest of the article here http://www.lawyersandsettlements.com/articles/15134/paxil-birth-defects-side-effects-pph-7.html

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Making a Market in Antipsychotic Drugs: An Ironic Tragedy

Thursday, September 23rd, 2010

The Huffington Post

September 23, 2010

by Dr. Peter Breggin

Remember not so long ago when Prozac became the world’s largest selling medication of any kind, and then for years how Prozac, Paxil and Zoloft took over many of the top 10 spots? Remember the explanations at the time–that they were wonder drugs and that 15-50 percent or more of Americans would need them some time in their lives? To many people this seemed like a scientific breakthrough when in reality it was … a triumph of marketing.   Some studies suggest that the antidepressants are little or no more effective than a sugar pill and a lot more dangerous. Recent research examined all antidepressant studies submitted in recent years to FDA in regard to antidepressant efficacy and found that the drug performed no better than placebo except in “severely depressed patients,” reaching “clinical significance” only “at the upper end of the very severely depressed category.” Even then, the difference between the antidepressant and the placebo was “relatively small.”

In addition to being largely ineffective, the antidepressants can be very distressing to withdraw from, which keeps the market artificially inflated by people who would desperately like to stop but find the process too emotionally or physically painful. Often these individuals fail to realize that they are undergoing withdrawal and instead mistakenly conclude that they “need” the medication to control their original psychiatric problems.

Now look what have become the new top selling drugs in the world: antipsychotic drugs like Risperdal, Zyprexa, Abilify, Seroquel, Geodon and Invega. Although the FDA has been expanding the approved use of some of these drugs to some cases of autism, Tourettes and a variety of other problems, their original purpose and their main use in psychiatry until now has been largely confined to psychosis and acute mania. Psychosis and acute mania afflict a very small portion of the the population. Yet these drugs are now at the top of the list of most widely prescribed medications worldwide. How did these incredibly toxic chemicals become daily pharmacological mainstays for so many millions of children and adults? It’s time to face the truth that the prescription of psychiatric drugs is driven by marketing trends–and now for the first time by something even more dreadful and insidious than mere marketing.

To begin their market campaigns for the newer antipsychotic agents, the drug companies created the myth that these products were not as dangerous as the old antipsychotic drugs, which were becoming recognized as highly toxic. Especially hard to ignore, it was demonstrated that the old antipsychotics cause tardive dyskinesia, a disfiguring and sometimes disabling array of abnormal movements in 5-8 percent per year cumulative of otherwise healthy patients and more than 20 percent of older patients. But even the unproven and ultimately false claim that the newer drugs were safer could not make a huge market for them. Even if these were wonder drugs, they were wonderful for a relatively tiny percent of the population. The drug companies had to create a new patient population market and that market became “bipolar disorder.”

Once much rarer than schizophrenia, bipolar disorder would soon become one of the most common diagnoses made in medicine and psychiatry. Indeed, while ordinary folks used to talk about their biochemical imbalances and depression, now they’ve upgraded to having bipolar disorder.

Lithium, once the magic bullet without side effects for bipolar disorder–then called manic-depressive disorder–had turned out to be a severe central nervous system toxin that over the years ruins mental function while also producing thyroid disorders, kidney failure and a host of other serious problems. The discrediting of lithium created a new niche for antipsychotic drugs–to be used as “mood stabilizers” for people with severe ups and downs. But it was a relatively smalll niche to begin with.

Where would all the new bipolar patients come from? Many of them would come from the fertile imagination of drug company sponsored psychiatrists who found bipolar disorder in everything from toddlers with temper tantrums to adults with bursts of energy followed by a natural period of feeling fatigued. Leaders in child psychiatry like Harvard’s Joseph Biederman were literally paid under the table to push antipsychotic medications for bipolar disorder in children. A recent study showed that children labeled bipolar actually receive more adult antipsychotic drugs than adults labeled bipolar . Another recent study covering 2000-2002 showed that 18 percent of child visits to a psychiatrist included antipsychotic treatment, and 92 percent of those were for the newer so-called second generation drugs. It took a great deal of marketing to convince physicians that these relatively untried and highly toxic antipsychotic drugs are that safe and effective in children.

But even marketing bipolar disorder to the professions and the public was insufficient to create a huge enough market to satisfy the drug companies. Here’s where the irony of ironies came into play. The newer antidepressants–once the leading drugs in the world–frequently cause mania. They do so in millions of patients, children and adults alike, every year. These once most popular drugs in the world by causing mania made and continue to make the market for the next wave of most popular drugs–the antipsychotic drugs being used as mood stabilizers.

How common is antidepressant-induced mania? Very common. Several studies have found that 6 to 8 percent of patients exposed to antidepressants will develop a manic disorder. One research study, for example, found in a retrospective study that Paxil produced mania in 8.6 percent of patients exposed. Other studies find the rates as high as 17 percent And if a person has already shown a manic tendency or has experienced a manic-like episode, antidepressants will push one-quarter to one-third into new manias (For a review, see P. Breggin, Brain-Disabling Treatments in Psychiatry, 2008, pp. 157-165) . Yet misguided psychiatrists commonly give antidepressants to patients diagnosed with bipolar disorder. The result? Millions of people suffer from medication-induced mania and other expressions of what I call “medication madness.”

When I took my psychiatric residency at Harvard in Boston and at SUNY in Syracuse in the early 1960s, we never saw or diagnosed bipolar disorder in children. In my four years of training, I saw one 19-year-old in a manic state and a few adults. When a person was admitted in a manic condition talking a mile a minute, imagining grand things about themselves, making outrageous plans, bursting with anger and energy, unable to sleep and otherwise euphoric, the condition was so unusual that we would hold grand rounds, a medical show-and-tell, to discuss the patient.

Now psychiatric wards are filled with patients having their second and third or umpteenth manic episode and every psychiatrist’s day is filled with patients diagnosed bipolar. It’s mostly about antidepressant-induced mania. Every single child I have evaluated who has suffered what looks like a manic episode has been taking stimulants or antidepressants, both of which cause mania. At least 9 out of 10 adults I’ve seen in the last two decades who have suffered emotional episodes that could be diagnosed as mania had them in direct response to stimulants or antidepressants–mostly the newer antidepressants starting with Prozac.

In the official diagnostic system, these are not cases of bipolar mania but cases of medication induced mood disorder with manic features; but they are almost always mistakenly called bipolar disorder in order to avoid identifying the drug and the prescriber as the causative agents.

For those who want further details, I have reviewed all the studies mentioned in this report in my medical book, “Brain-Disabling Treatments in Psychiatry, Second Edition” (2008). In my popular book, “Medication Madness: The Role of Psychiatric Drugs in Cases of Violence, Suicide and Crime” (2008), I have provided dozens of in-depth illustrations of lives ruined by psychiatric drugs, especially the newer antidepressants.

Read the rest of the article here http://www.huffingtonpost.com/dr-peter-breggin/making-a-market-in-antips_b_720861.html

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PTSD and Anti-Depressant Drugs: the Worst Notorious Modern Medical Fraud

Tuesday, September 21st, 2010

Salem-news.com

September 21, 2010

by Dr. Phillip Leveque

Afghanistan
Afghanistan by Tim King Salem-News.com

(MOLALLA, Ore.) – I’m sure some people will take umbrage at my title. Keep on reading. First of all there are about 30 of them – why? It’s easy, most don’t work. In fact placebos (fake sugar pills) frequently work better.

Another point, their adverse side effects are horrible. Some even cause worse depression and even suicide. The main side effects are nausea, insomnia, anxiety, restlessness, decreased sex drive, dizziness, weight gain or loss, tremors, sweating, sleepiness, fatigue, dry mouth, diarrhea, constipation, headache, et cetera. Who needs that stuff?!? They also screw up ones head and balance with falls and fractures. If one stops taking them, the withdrawal symptoms sound worse than heroin. In addition to all this, some are addicting and it is very difficult to stop taking them.

This kind of drug or drugs has an extremely interesting origin. Around 1950 the first drug in this class was actually an anti-tuberculosis drug Isoniazid. For some reason it also acted as a brain stimulant, much like amphetamine. When this side effect was published by the T.B. doctors, other doctors decided to try it on depression patients. Prior to this certain Morphine-like cousin drugs and amphetamines were used for depression. They had severe addiction liability.

Isoniazid, the T.B. drug, was used on an experimental basis and the patients brain function improved dramatically. The psychiatrists who read about this tried Isoniazid on their depression patients and they coined the word ANTI-DEPRESSANT.

From then on starting about 1957 the Tricyclic drugs were born. They were relatives of anti-histamine drugs and they did combat depression. I think the first well known one was Elavil which is still in use. This type of drug drifted around quietly for several years searching for a disease all of the sudden it erupted – CLINICAL DEPRESSION. The first REAL drug Fluoxetine or PROZAC came out in 1988 by Ely Lilly & Co. It was heavily advertised and we soon had a epidemic of clinical depression spread all over the world.

I’m not going into a recital of the various kinds of anti-depressants. I think there is enough to indicate that at least 500,000,000 prescriptions are written per year and for the 14 or so leaders, each is worth up to several billion dollars to the drug companies.

As I said in the beginning placebos, or fake pills, work about as well as these chemicals and exercise or just plain talking to a psychologist may work as well. The drug companies advertise heavily in the millions of dollars to sell these drugs to doctors and patients. It is worth it. The anti-depressants bring in billions of dollars.

A side comment is that the drug companies have sold the idea to the Veterans Administration and they prescribe these drugs by the ton to PTSD Veterans. The evidence is that they don’t help much and cause a lot of harm.

http://www.salem-news.com/articles/september212010/ptsd-depressants-pl.php

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Americas Mental Illness Epidemic

Thursday, August 26th, 2010

Rense.com
By Gary G. Kohls, MD
August 25, 2010

Tens of millions of innocent, unsuspecting Americans, who are mired deeply in the mental “health” system, have actually been made crazy by the use of or the withdrawal from commonly-prescribed, brain-altering, brain-disabling, indeed brain-damaging psychiatric drugs that have been, for many decades, cavalierly handed out like candy ­ often in untested and therefore unapproved combinations of drugs – to trusting and unaware patients by equally unaware but well-intentioned physicians who have been under the mesmerizing influence of slick and obscenely profitable psychopharmaceutical drug companies aka, BigPharma.

That is the conclusion of two books by investigative journalist and health science writer Robert Whitaker. His first book, entitled Mad in America: Bad Science, Bad Medicine and the Enduring Mistreatment of the Mentally Ill noted that there has been a 600% increase (since Thorazine was introduced in the US in the mid-1950s) in the total and permanent disabilities of millions of psychiatric drug-takers. This uniquely First World mental ill health epidemic has resulted in the life-long taxpayer-supported disabilities of rapidly increasing numbers of psychiatric patients who are now unable to be happy, productive, taxpaying members of society. Whitaker has done a powerful, albeit unwelcome job of presenting previously hidden, but very convincing evidence to support his thesis, that it is the drugs and not the diagnosis that is causing the epidemic of mental illness disability. Many open-minded physicians and many aware psychiatric patients are now motivated to be wary of any and all synthetic chemicals that can cross the blood/brain barrier because all of them are capable of altering the brain in ways totally unknown to medical science, especially when the patients are taking the drugs long-term..

In Whitaker’s second book Anatomy of an Epidemic: Magic Bullets, Psychiatric Drugs, and the Astonishing Rise of Mental Illness in America, he goes much further in advancing this sobering reality. He documents the history of the powerful forces behind the relatively new field of psychopharmacology and its major shaper and beneficiary, BigPharma. Psychiatric drugs, whose developers, marketers and salespersons are all in the employ of the giant drug companies, are far more dangerous than the drug and psychiatric industries are willing to admit: These drugs, it turns our, are fully capable of disabling ­ often permanently – body, brain and spirit.

More evidence to support Whitaker’s well-documented claims are laid out in two important new books written by psychiatrist and scholar Grace Jackson. Jackson did a beautiful job of researching and documenting, from the voluminous basic neuroscience research (which is uniformly ignored by the clinical sciences) the unintended and often disastrous consequences of the chronic ingestion of any of the five major classes of psychiatric drugs. Her second and most powerful book: Drug-Induced Dementia: A Perfect Crime, proves beyond a shadow of a doubt, that any of the five classes of drugs that are commonly used in psychiatric patients (antidepressants, antipsychotics, psychostimulants, tranquilizers and anti-seizure/”mood-stabilizer” drugs) have shown microscopic, macroscopic, biochemical, clinical and/or radiological evidence of brain shrinkage and other signs of brain damage, which can result in clinically-diagnosable, permanent dementia, premature death and a variety of other related brain disorders that can mimic mental illnesses. Jackson’s first book, Rethinking Psychiatric Drugs: A Guide for Informed Consent was an equally sobering book warning about the many hidden dangers of psychiatric drugs.

This sad truth is that the seemingly knee-jerk prescribing (without very much information being given to patients about the long list of serious long-term adverse effects) of potent and often addicting/dependency-inducing psychiatric drugs has become the standard of care in American psychiatry since the introduction of the so-called anti-schizophrenic “miracle” drug Thorazine in the mid-1950s. (Thorazine was the offending drug that all of Jack Nicholson’s fellow patients were coerced into taking at “medication time” in the Academy Award-winning movie “One Flew Over the Cuckoo’s Nest”.) Thorazine and all the other “me-too” early antipsychotic drugs are now universally known to have been an iatrogenic (= doctor or other treatment-caused) disaster because of their serious long-term, initially unsuspected, brain-damaging effects that resulted in a number of incurable neurological disorders such as tardive dyskinesia and Parkinson’s disease.

Thorazine and all the other knock-off drugs like Prolixin, Mellaril, Navane. etc, are synthetic “tricyclic” chemical compounds similar in molecular structure to the tricyclic “antidepressants” like imipramine and the similarly toxic, obesity-inducing, diabetogenic, “atypical” anti-schizophrenic drugs like Clozaril, Zyprexa and Seroquel.

Thorazine, incidentally, was originally developed in Europe as an industrial dye. That doesn’t sound so good although it may not be so unusual in the closely related fields of psychopharmcology and the chemical industry, especially when one considers that Depakote, a popular drug marketed initially as an anti-epilepsy drug but now is being heavily used as a so-called “mood stabilizer”. Depakote, known to be a hepatotoxin and renal toxin, was originally developed as an industrial solvent capable of dissolving fat – including, presumably, the fatty tissue in human livers and brains.

Some sympathy and understanding needs to be generated for the various victims of BigPharma’s compulsive drive to expand market share and “shareholder value” (share price, dividends and the next quarter’s financial report) by whatever means necessary. Both the prescribers and the swallowers of BigPharma’s drugs have succumbed to BigPharma’s cunning marketing campaigns, the prescribers having been seduced by attractive drug company representatives and their “pens, pizzas and post-it note” freebies in the office, and the patients being brain-washed by the inane and unbelievable (if one has intact critical thinking skills) commercials on TV that quickly gloss over the lethal adverse effects in the fine print while urging the watcher to “ask your doctor” about the latest unaffordable wannabe blockbuster drug..

For a quick overview of these issues, I recommend that everybody with an open mind read a long essay written by Whitaker that persuasively identifies the source of America’s epidemic of mental illness disability (a phenomenon that doesn’t exist in Third World nations because costly psych drugs are not prescribed so cavalierly as in the US).

Whitaker and Jackson (among a number of other ground-breaking and whistle-blowing authors who have been essentially black-listed by the mainstream media and mainstream medical journals) have proven to most critically-thinking scientists, alternative practitioners and assorted “psychiatric survivors” that it is the drugs – and not the so-called “disorders” – that are causing our nation’s epidemic of mental illness disability. The Whitaker essay, plus other pertinent information about his books can be accessed at www.madinamerica.com A recent interview on Wisconsin Public Radio can be accessed at www.wpr.org (at their radio archives link) and a long interview with Dr.Joseph Mercola can be heard at: http://articles.mercola.com/sites/articles/archive/2010/05/08/robert-whitaker-interview.aspx

After reading and studying all these inconvenient truths, mental health practitioners must consider the medicolegal implications for them, especially if the information is ignored or if the information is dismissed out of hand by practitioners who might be tempted to not take the time to study this new information. Those people who are hearing about this for the first time need to pass the word on to others, especially their prescribing healthcare practitioners who should be equally concerned. This is important because the opinion leaders in the highly influential (for good or ill) psychiatric and medical industries have been marketed into submission without hearing the all the facts (which may have been intentionally hidden from them. If that is the case, they cannot be automatically blamed for proceeding in a practice that some day might represent malpractice. It shouldn’t have to be pointed out that is the solemn duty of ethical practitioners who are in positions of authority to fully examine potential malpractice issues and then warn others, especially their patients, of the dangers.

Sadly, it must be admitted that most of the over-worked, double-booked care-givers in medical clinics have not yet heard the news that most if not all of the brain-altering synthetic chemicals known as psychotropic drugs (which are treated as hazardous waste unless they are packaged in a swallowable capsule!) have been marketed as safe and effective – but only for short-term use. The captains of the drug industry know that the psychotropic drugs that they present for the FDA-approval have only been tested in animal trials for days and in clinical trials for 6 weeks. They also know ­ indeed they hope – that patients will be taking their drugs for years (despite no long-term trials proving safety and efficacy) as the only “treatment” for mental ill health. They know that their brain-altering drugs are also dependency-inducing (aka addicting, causing withdrawal symptoms when stopped), neurotoxic and increasingly ineffective (a la “Prozac Poop-out”) as time goes by.

The truth is that the people diagnosed as “mentally ill” for life are often simply those unfortunates who find themselves in acute or chronic states of crisis or “overwhelm” due to any number of preventable, curable and treatable (without the use of drugs) bad luck accidents such as poverty, abuse, violence, torture, homelessness, discrimination, underemployment, brain malnutrition, addictions/withdrawal, brain damage from electroshock “therapy” and/or exposure to neurotoxic chemicals in their food, air, water or prescription bottles.

Those labeled as the “mentally ill” are just like us “normals” who have not yet decompensated because of some yet-to-happen, crisis-inducing, overwhelming (however temporary) life situation. And thus we have not yet been given a billable code number (accompanied by the seemingly obligatory – and unaffordable – drug prescription or two signifying we are now chronically mentally ill. Unlabeled, we are likely to remain off prescription drugs but with a label and in “the system”, it is hard to “just say no to drugs.”

The victims of hopelessness-generating situations like simple bad luck, bad circumstances, bad company, bad choices, bad government, big business, and a competitive society that generates a few winners but mostly losers. America tolerates, indeed celebrates, punitive and thus fear-inducing social systems resembling in many ways the infamous police state realities of 20th century European totalitarianism, where people who were different or just dissidents were thought to be abnormal and therefore “disappeared” into insane asylums, jails or concentration camps without just cause or competent legal defense. And many of them were and are drugged with disabling psychoactive chemicals against their will.

The truth is that most, if not all, of BigPharma’s psychotropic drugs are lethal at some dosage level (the LD50, the lethal dose that kills 50% of lab animals, is calculated before efficacy testing is done), and therefore the drugs must be regarded as dangerous. The chronic use of these drugs is a major cause of cognitive disorders, brain damage, loss of creativity, loss of spirituality, loss of empathy, loss of energy, loss of strength, fatigue and tiredness, permanent disability and a multitude of metabolic adverse effects that can readily sicken the body, brain and soul by causing insomnia or somnolence, increased depression or anxiety, delusions, psychoses, paranoia, mania, etc. So before filling the prescription, it is advisable to read the product insert labeling under WARNINGS, PRECAUTIONS, ADVERSE EFFECTS, CONTRAINDICATIONS, TOXICOLOGY, OVERDOSAGE and the ever-present BLACK BOX WARNINGS ABOUT SUICIDALITY.

Long-term, high dosage or combination psychotropic drug usage could be regarded as a chemically traumatic brain injury (TBI) or, as drugs like Thorazine were known in the 1950s and 60s, a “chemical lobotomy”. That is a useful way to conceptualize this serious issue, because such chemically brain-altered patients are often indistinguishable from those who have suffered a physically traumatic brain injuries or been subjected to ice-pick lobotomies which were popular in the 1940s and 50s – before the drugs came on the market.

America has a mental ill health epidemic on its hands that is grossly misunderstood because it is worsening, not by the supposed disease progression, but because of the neurotoxic, non-curative drugs that are somehow regarded as first-line “treatment.”
Read the rest of this article here: http://www.rense.com/general91/edi.htm

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Prescription Drug Epidemic Spreads to Babies

Friday, July 16th, 2010

St. Petersburg Times
By Richard Martin
July 16, 2010

Dr. Mary Newport sees the symptoms more and more in the babies she treats: oddly stiff limbs, severe tremors, vomiting, diarrhea, insomnia, crying that never stops.

The common denominator: Their mothers were taking prescription drugs, mostly painkillers like OxyContin and Vicodin, and antianxiety drugs like Xanax during pregnancy.

Some of the moms had no idea these medications would hurt their developing babies — after all, it’s not like it’s heroin or cocaine, many think.

“They are seriously misinformed,” said Newport, medical director of Spring Hill Regional Hospital’s neonatal intensive care unit.

The prescription drug epidemic, well documented among teens and adults, now is claiming victims before they are even born. Tampa Bay area doctors and addiction specialists are reporting a dramatic increase in the number of pregnant addicts and infants needing treatment for withdrawal from prescription drugs.

The trend is reminiscent of the “crack baby” epidemic of the 1980s, when mothers used crack cocaine during their pregnancies.

But area neonatologists say that in some ways, the current trend is worse. Some women don’t understand that prescription drugs can be dangerous during pregnancy. Others decide to stop the drugs as soon as they learn they are pregnant, causing sudden withdrawal that can lead to miscarriage.

And doctors say that treating a baby with drugs like oxycodone, methadone or Xanax in the system takes longer, and involves more medication, than treatment for heroin or cocaine.

“Babies are suffering more,” said Dr. Terri Ashmeade, medical director of Tampa General Hospital’s neonatal intensive care unit. “Withdrawal patterns seem to be worse (with prescription drugs) than what we were seeing with heroin.”

Note from CCHR Int: To see for yourself what psychiatric drug reactions for infants and babies have been reported to the U.S. FDA’s medwatch system (by doctors, pharmacists, consumers etc),  go to our decrypted Medwatch reports: Under the drop down menu for DRUG NAME/DRUG CLASS, scroll all the way down to the bottom until you see CLASS OF DRUGS such as ATYPICAL ANTIPSYCHOTICS or ANTIDEPRESSANTS or STIMULANTS and select one of those.   In the AGE RANGE drop down menu select 0-1 year old then click GENERATE REPORT.   You can do this for each class of psychiatric drug.  And consider this,   by the FDA’s own admission, only 1-10% of side effects are ever reported, so the actual side effects occurring in the general population are much higher.

Click here for Decrypted Medwatch Reports http://www.cchrint.org/psychdrugdangers/medwatch_psych_drug_adverse_reactions.php

Click her to read the rest of the article:  http://www.tampabay.com/news/health/article1109348.ece

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