CCHR International » Pregnancy

Paxil and Prozac Linked to Risk of Heart Birth Defects

admin — Tue, 28 Jun 2011 00:27:42 +0000

AboutLawSuits.com – June 27, 2011

According to Finnish researchers, doctors should avoid prescribing Paxil or Prozac to pregnant women, due to the potential risk of heart birth defects.

In a study published in Obstetrics & Gynecology medical journal, researchers found that side effects of Prozac and Paxil use during pregnancy may increase the risk of women giving birth to children with congenital heart defects. Both drugs belong to a class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs).

Researchers looked at national data from Finland on 635,583 births occurring between 1996 and 2006, and found that 31 out of every 10,000 women who took Paxil during pregnancy gave birth to children with right ventricular outflow tract defects that affect blood flow from the right chambers of the heart to the rest of the body, more than four times the frequency of births among women who did not take Paxil. For those who took Prozac, 105 babies born out of every 10,000 had isolated ventrical septal defects; a hole between the left and right sides of the heart, which was more than double the rate of babies born to women who did not take the drug.

The researchers also found that women who took any SSRI antidepressant during pregnancy were more than twice as likely to give birth to a child with a neural tube defect; 22 out of every 10,000 newborns, as compared to 9 out of every 10,000 newborns born to women who did not take any SSRI during pregnancy.

SSRIs are a relatively new class of antidepressants, which help reduce symptoms of depression by preventing certain nerve cells in the brain from re-absorbing the chemical serotonin. These drugs are commonly used by millions of Americans with depression.

Although the drugs have been found to cause fewer side effects than older anti-depressants, research has shown that users of the drugs could also face an increased risk of suicides, and use during pregnancy has been linked to a risk of birth defects, especially among users of Paxil.

Prozac (fluoxetine) is marketed by Eli Lilly and is approved for the treatment of depression, obsessive-compulsive disorder (OCD) and other psychiatric problems. In 2007 there were more than 22 million Prozac prescriptions in the United States.

Paxil (paroxetine) is a selective serotonin reuptake inhibitor prescribed to treat depression. Approved in 1992, it has become one of the most commonly prescribed drugs in the United States, with sales of just under $1 billion in 2008.

In December 2005, the FDA issued an alert about the risk of birth defects from Paxil after studies showed the drug could increase the risk of the heart defects when taken during the first three months of pregnancy. At that time, the agency also required GlaxoSmithKline to update the warning label to include information about the risk of birth defects from Paxil side effects.

The company reportedly agreed to settle hundreds of Paxil heart birth defect lawsuits last year. The Paxil lawsuits were filed by parents who say that the use of the antidepressant during pregnancy caused persistent pulmonary hypertension in newborns (PPHN) and other birth defects. The lawsuits claimed that the company failed to warn consumers and doctors that use of Paxil during pregnancy could lead to congenital heart defects in newborns. The lawsuits also claimed that the company purposefully hid test results that would have revealed the side effects of Paxil and misled doctors.

http://www.aboutlawsuits.com/paxil-prozac-birth-defect-study-19139/

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FDA Issues Label Changes for Antipsychotic Drugs—Outlining risks for newborns whose mothers took drug

admin — Wed, 23 Feb 2011 21:38:31 +0000

ModernMedicine – Feb 22, 2011

TUESDAY, Feb. 22 (HealthDay News) — The U.S. Food and Drug Administration has notified health care providers that the Pregnancy section of drug labels for the entire class of antipsychotic drugs has been updated. The new drug labels include additional and consistent information regarding the potential risk for abnormal muscle movements (extrapyramidal signs [EPS]) and withdrawal symptoms among newborns whose mothers received the drugs in the third trimester of pregnancy.

The drug labels were updated based on information from the FDA’s Adverse Event Reporting System database, which revealed 69 cases of neonatal EPS or withdrawal with all antipsychotic drugs. Most cases were attributable to multiple factors, but some neonatal EPS and withdrawal cases may have occurred due to antipsychotics alone.

The symptoms of EPS and withdrawal in infants include agitation, abnormally increased or decreased muscle tone, tremor, sleepiness, severe difficulty breathing, and difficulty in feeding. Symptoms may subside in a few hours or days and may not require treatment, but some newborns may require longer hospitalizations.

According to the FDA, “health care professionals should be aware of the effects of antipsychotic medications on newborns when the medications are used during pregnancy. Patients should not stop taking these medications if they become pregnant without talking to their health care professional, as abruptly stopping antipsychotic medications can cause significant complications for treatment.”

http://www.modernmedicine.com/modernmedicine/Modern+Medicine+Now/FDA-Issues-Label-Changes-for-Antipsychotic-Drug-Cl/ArticleNewsFeed/Article/detail/708731?contextCategoryId=40130

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Update of Swedish Study Upholds Concern for Antidepressant Induced Birth Defects

admin — Sun, 14 Nov 2010 15:29:36 +0000

LawyersandSettlements, November 13, 2010

by Gordon Gibb

Swedish research on maternal use of antidepressants in pregnancy continues to bolster existing concerns about SSRI birth defects, according to a recent issue of Obesity, Fitness & Wellness Week (OFWW). “Concerns have been expressed about possible adverse effects of the use of antidepressant medication during pregnancy, including risk for neonatal pathology and the presence of congenital malformations,” according to the authors of the study.

According to the September 18th issue of OFWW, the researchers used data from the Swedish Medical Birth Register from July 1995 through 2007. Women who reported the use of antidepressants in early pregnancy, or were prescribed antidepressants during pregnancy by antenatal care, were identified for the study.

The end number for study purposes was 14,821 women with 15,017 infants.

“Maternal characteristics, maternal delivery diagnoses, infant neonatal diagnoses and the presence of congenital malformations were compared with all other women who gave birth, using the Mantel-Haenszel technique and with adjustments for certain characteristics,” the authors noted.

“There was an association between antidepressant treatment and pre-existing diabetes and chronic hypertension, but also with many pregnancy complications. Rates of induced delivery and caesarean section were increased.”

The study authors noted that neonatal complications were common, especially with regard to the use of tricyclic (TCA) antidepressant use. “An increased risk of persistent pulmonary hypertension of the newborn (PPHN) was verified. The congenital malformation rate was increased after TCAs,” wrote M. Reis and colleagues.

The conclusion?

“Use of TCAs was found to carry a higher risk than other antidepressants, and paroxetine (Aropax, Paxil, Seroxat) seems to be associated with a specific teratogenic property.”

Paxil, one of the antidepressants mentioned, is a drug belonging to the SSRI class (selective serotonin reuptake inhibitor) and includes a host of SSRI side effects. One of the most grievous adverse reactions is PPHN, or persistent pulmonary hypertension of the newborn. The latter is considered a serious birth defect.

M. Reis is affiliated with the National Board of Forensic Medicine, Department of Forensic Genetics and Forensic Toxicology, Linkoping, Sweden. The study authored by Reis and colleagues updates a previous study and was published in the Journal of Psychological Medicine, published out of New York.

http://www.lawyersandsettlements.com/articles/15389/ssri-birth-defects-side-effects-pphn-swedish.html

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Antidepressant Drugs Are Not Safe During Pregnancy—No Matter What the Pharma Shills Say

admin — Fri, 05 Nov 2010 01:50:44 +0000

by CCHR International

November 4, 2010

Medical News Today published an article entitled “Increased Depression Screening Needed During Pregnancy, Study Says,” that is so highly misleading, we wonder if they ever bother checking the validity of what they’re forwarding under the guise of “medical news.”

We’re going to make this really simple—the study and its findings are bogus not to mention highly misleading and we’re only going to take up the two most egregious “facts” of the article to make our point.

The article states, “The authors of the study say their findings suggest that screening for depression should be a routine part of prenatal and postnatal care. They conducted a 10-week pilot project at WIC clinics in Santa Fe and Las Vegas, N.M., finding that 109 of 467 women who were screened had a high enough score on the Edinburgh Postnatal Depression Scale to require a referral.”

FACT: The Edinburgh Postnatal Depression Scale—also called EPDS, is a screening method documented to triple the number of women diagnosed with Post partum depression, according to a study published in Obstecrics & Gynecology. The Scandinavian Journal of Public Health stated that EPDS screening was so unethical it should not be used.

So the authors are knowingly promoting a study which is known to triple the amount of women diagnosed postpartum depression, has been called so unethical it should not be used.

Next, the article states, “There are antidepressants that are safe to take during pregnancy”

False.

FACT: Four countries have done nine studies on the effects of antidepressants during pregnancy or breast feeding. They found that newer and older antidepressants can cause premature births, and increase the risk of cardiovascular interventions such as heart surgery in early childhood. In addition, newer antidepressants could also cause withdrawal symptoms, respiratory problems, and neurological problems.

Six counties have issued a total of 15 drug regulatory warnings on antidepressants causing severe problems for newborns.

They warn of:

Newer antidepressants causing seizures,
Wellbutrin, Cipralex, Luvox, Remeron, Effexor and Zyban increasing the risk of a life-threatening lung condition in newborns,
Zoloft and Celexa causing withdrawal symptoms and increasing the risk of a life-threatening lung condition in newborns,
Paxil and Prozac causing withdrawal symptoms and increasing the risk of cardiovascular birth defects and a life-threatening lung condition in newborns

Like we said, the article and the “findings” are highly misleading to say the least.

We’d also like to suggest something to any press forwarding these psycho/pharma puff pieces— Its called Google Search. Its pretty easy these days to check the facts before promoting bogus studies and or “findings” that are not only false, but can harm pregnant women and can give false information under the guise of “medical news.” We also recommend that anyone reporting on psychiatric drugs at least check our psychiatric drug database to see what international drug regulatory agencies and international studies have warned about these drugs instead of just regurgitating the latest pro drug study http://www.cchrint.org/psychdrugdangers/

Here is a very short video of what can happen to pregnant women when they are not given the facts about these drugs:

In Memory of Matthew Schultz / Effexor Baby Pregnancy Infant Death

http://www.youtube.com/watch?v=qnxuw2ufSug&p=7F22F2C419977E5A&playnext=1&index=70

And finally, the “Medical News” article:

Increased Depression Screening Needed During Pregnancy, Study Says

Medical News Today

Twenty-three percent of pregnant women screened at two Women, Infant and Children clinics in New Mexico met criteria for depression, according to a study by a work group of the New Mexico Health Department and state Human Services Department, the Albuquerque Journal reports.

Nationwide, 10% to 16% of pregnant women meet the criteria for depression, and 70% show some depressive symptoms, according to the American College of Obstetrics and Gynecologists. In June, ACOG said that screening of pregnant women for depression should be “strongly considered” but that there is not enough evidence to recommend it.

The authors of the new study say their findings suggest that screening for depression should be a routine part of prenatal and postnatal care. They conducted a 10-week pilot project at WIC clinics in Santa Fe and Las Vegas, N.M., finding that 109 of 467 women who were screened had a high enough score on the Edinburgh Postnatal Depression Scale to require a referral. The work group recommended increased training on depression screening tools for providers and more support groups for women, in both English and Spanish.

Signs of depression in pregnant women include feeling dread about the pregnancy, anxiety, isolation from loved ones, suicidal thoughts, self-harm, constant sadness, changes in appetite and lack of ability to experience pleasure, according to therapist Stefanie Luna. Doctors say leaving severe depression untreated could increase the risk for low birthweight or premature birth. When women are depressed they also are less likely to care for themselves and more likely to drink or smoke. There are antidepressants that are safe to take during pregnancy (Schoenberg, Albuquerque Journal, 11/1).

http://www.medicalnewstoday.com/articles/206701.php

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Prescription Drug Epidemic Spreads to Babies

cchrint — Fri, 16 Jul 2010 18:20:49 +0000

St. Petersburg Times
By Richard Martin
July 16, 2010

Dr. Mary Newport sees the symptoms more and more in the babies she treats: oddly stiff limbs, severe tremors, vomiting, diarrhea, insomnia, crying that never stops.

The common denominator: Their mothers were taking prescription drugs, mostly painkillers like OxyContin and Vicodin, and antianxiety drugs like Xanax during pregnancy.

Some of the moms had no idea these medications would hurt their developing babies — after all, it’s not like it’s heroin or cocaine, many think.

“They are seriously misinformed,” said Newport, medical director of Spring Hill Regional Hospital’s neonatal intensive care unit.

The prescription drug epidemic, well documented among teens and adults, now is claiming victims before they are even born. Tampa Bay area doctors and addiction specialists are reporting a dramatic increase in the number of pregnant addicts and infants needing treatment for withdrawal from prescription drugs.

The trend is reminiscent of the “crack baby” epidemic of the 1980s, when mothers used crack cocaine during their pregnancies.

But area neonatologists say that in some ways, the current trend is worse. Some women don’t understand that prescription drugs can be dangerous during pregnancy. Others decide to stop the drugs as soon as they learn they are pregnant, causing sudden withdrawal that can lead to miscarriage.

And doctors say that treating a baby with drugs like oxycodone, methadone or Xanax in the system takes longer, and involves more medication, than treatment for heroin or cocaine.

“Babies are suffering more,” said Dr. Terri Ashmeade, medical director of Tampa General Hospital’s neonatal intensive care unit. “Withdrawal patterns seem to be worse (with prescription drugs) than what we were seeing with heroin.”

Note from CCHR Int: To see for yourself what psychiatric drug reactions for infants and babies have been reported to the U.S. FDA’s medwatch system (by doctors, pharmacists, consumers etc), go to our decrypted Medwatch reports: Under the drop down menu for DRUG NAME/DRUG CLASS, scroll all the way down to the bottom until you see CLASS OF DRUGS such as ATYPICAL ANTIPSYCHOTICS or ANTIDEPRESSANTS or STIMULANTS and select one of those. In the AGE RANGE drop down menu select 0-1 year old then click GENERATE REPORT. You can do this for each class of psychiatric drug. And consider this, by the FDA’s own admission, only 1-10% of side effects are ever reported, so the actual side effects occurring in the general population are much higher.

Click here for Decrypted Medwatch Reports http://www.cchrint.org/psychdrugdangers/medwatch_psych_drug_adverse_reactions.php

Click her to read the rest of the article: http://www.tampabay.com/news/health/article1109348.ece

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New Study—Psychiatric Drugs Cause Birth Defects— pregnant women warned about smoking/alcohol but not psychiatric drugs

cchrint — Tue, 06 Jul 2010 20:21:21 +0000

Lawyers and Settlements
By LAS Newswire
July 6, 2010

Copenhagen, Denmark: A recent Danish study found a high number of Prozac birth defects among the children of women who took the drug while pregnant.

The study, conducted by the University of Copenhagen, warns that Prozac and other psychotropic drugs can cause serious birth defects and other maladies, according to United Press International.

Researchers discovered 429 instances of adverse reactions when women took the drugs while pregnant. Of those 429 cases, more than half involved serious reactions and a number of them involved birth defects.

“We are constantly reminded about the dangers of alcohol use and smoking during pregnancy, but there is no information offered to women with regards to use of psychotropic medication,” researcher Lisa Aagaard said in a statement. “There is simply not enough knowledge available in this area.”

Researchers found that 42 percent of the reactions were linked to psychostimulants like Ritalin, 31 percent to antidepressants such as Prozac and 24 to anti-psychotics like Haldol.

Read entire article: http://www.lawyersandsettlements.com/articles/14468/prozac-pphn-birth-defects-lawyer-3.html

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Medscape – Psychotropic Medications Linked to Serious Adverse Drug Reactions in Children

cchrint — Fri, 02 Jul 2010 22:02:27 +0000

Medscape
By Deborah Brauser
July 2, 2010

Psychotropic medications are associated with adverse drug reactions (ADRs), many of which are serious, in children younger than 17 years, according to a new database study from Danish researchers.

Results also showed that all but one of the psychotropic-related ADRs for children between the ages of birth and 2 years were serious, including birth defects such as neonatal withdrawal syndrome, ventricular septal defects, and premature labor.

These findings were “probably due to the mothers’ intake of psychotropic medicine, primarily antidepressants and antipsychotics, during pregnancy,” write the study authors.

For the overall patient population, the largest share of reported ADRs came from psychostimulants (42%), followed by antidepressants (31%) and antipsychotics (24.5%).

“The high number of serious ADRs reported for psychotropic medicines in the pediatric population should be a concern for health care professionals and physicians,” the study authors write.

In addition, “clinicians must be aware of the risks for the unborn child if they treat pregnant women with [these drugs],” coinvestigator Ebba Hansen, MSc, professor of social pharmacy and director for the FKL-Research Center for Quality in Medicine Use at the University of Copenhagen, Denmark, told Medscape Medical News.

She noted that many of the general practitioners interviewed for this study “thought that SSRI [selective serotonin reuptake inhibitor] antidepressants are harmless. Therefore, we recommend that treatment of pregnant women with psychotropic drugs should be an issue for specialists only.”

The study is published online in BMC Research Notes.

ADR Evidence Lacking

Although regulatory authorities have issued warnings about risks associated with the use of psychotropics in pediatric patients, “little evidence has been reported about the ADRs of these medicines in practice,” write the study authors.

“Overall, we have very little information about [ADRs] in children, and especially in infants, as vulnerable groups are excluded from the clinical trials that document a medication’s efficacy and safety before licensing and marketing,” said Professor Hansen.

For this study, her team evaluated 4500 ADRs in children listed in the national Danish ADR database between 1998 and 2007.

“Spontaneous ADR reporting [is] an important contributor to knowledge about safety of medicines,” the study authors write. They note that spontaneous reports are “the main source for information about new and previous unknown ADRs.”

Serious ADRs Found

Results showed that 429 of the ADRs reported during the study period were for psychotropic medications. Of these, 241 (56%) were deemed serious.

A total of 50% of the psychotropic ADRs reported were for adolescents between the ages of 11 and 17 years (n = 214), of which 45% were serious. Almost 19% were for children between the ages of birth and 2 years (n = 80).

In addition, 39% of the overall psychotropic-related ADRs were from the “nervous and psychiatric disorders” categories. When looking at sex, 59% of the total ADRs reported were for boys.

A total of 79 of the 80 ADRs associated with psychotropics in the children younger than 2 years were serious, and 2 of these were fatal (one was associated with citalopram due to chorioamnionitis and the other with fluoxetine due to persistent fetal circulation).

Finally, 40% of all psychotropic ADRs were associated with the psychostimulants methylphenidate and atomoxetine, whereas 59% of the ADRs reported for antipsychotics were associated with ziprasidone, olanzapine, and risperidone. A total of 61% of the total ADRs reported for antidepressants were with sertraline and citalopram.

Read entire article: http://www.medscape.com/viewarticle/724547
(Free registration required for Medscape)

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INFOWARS.COM — Madhouse Medical Tyranny: When Health Becomes Sickness

cchrint — Fri, 02 Jul 2010 17:09:49 +0000

INFOWARS.COM
By John Galt
July 2, 2010

Dictatorships know that the battle for complete control is ultimately won or lost in the minds of the target population. As the oppression advances, it tends to move from propaganda mind control to the direct intervention into the mind via pharmaceuticals. We are now seeing the overt global coordination of the psychiatry profession to convince every resident of planet Earth that all clear thinking, healthy living, and wholesome innocence is some kind of disorder that needs to be corrected (suppressed) with drugs to render zombie-like those whose instincts afford them the ability of discernment.

We have seen this before — the role of the medical establishment in dictatorships such as Nazi Germany is well documented. It is the pre-Endgame, if you will, before the final culling takes place. The proof that we are being led by a medical tyranny to soften us up for population reduction is of course not something to make light of. However, it is absurd, because it is a manufactured attempt to re-define the natural human condition. So, let us get up to speed on our mental disorders as a gallows humor descends.

Independent Thinking

This disorder is naturally a wide-ranging one, as each unique human being tends to have opinions. Some of the more deviant forms of individuality are questioning authority and anxious distress, which includes symptoms like the “fear that something awful may happen.” Like the fear that individuality will be declared a mental disorder by a scientific dictatorship?

Emotions

The natural highs and lows that come with being a sentient human being experiencing the joys and sorrows of life apparently need to be eradicated. Happiness tests should be given to children to be sure that they feel elated at all times, and perfectly at peace with their indoctrination. If not, be sure to take your happy pills each day.

Healthy Eating

Concern for your own well-being is apparently in direct opposition to the goals of those who wish to keep the population fat, dumb, and toxic. Mike Adams gives a run-down on the latest crazy thinking associated with eating broccoli, taking vitamins and minerals, drinking purified water, and avoiding known toxins.

Pregnancy

The act of experiencing the emotions of childbirth is definitely something that needs strong legislation. Instead of thinking about creating life, and the family bonding process, it is much healthier instead to focus on the increasing numbers of disorders surrounding the most natural of processes and how the medical establishment can keep mothers worried sick about their babies.

And Now: BEING BORN

The Psychiatric Dictatorship has begun in earnest to target infants as mental patients. The amniotic world and the newly born are now under surveillance by agents of the medical elite such as John H. Gilmore, Director of the UNC Schizophrenia Research, for signs of schizophrenia. Unfortunately, Gilmore is not an isolated mad scientist; this is a global initiative. The Citizens Commission on Human Rights International recently covered the story of “Australian of the Year,” Patrick McGorry, who would like Australia to lead the world in treating mental illness. Consulting fees and research grants are raining down on pre-detection initiatives from all of the major pharmaceutical peddlers.

Read entire article: http://www.infowars.com/madhouse-medical-tyranny-when-health-becomes-sickness/

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University of Copenhagen; Psychiatric Drugs Cause Birth Defects—responsibility must be taken to warn pregnant women

cchrint — Mon, 28 Jun 2010 23:36:39 +0000

HealthJockey.com
June 28, 2010

Some psychotropic drugs may be recommended to treat depression as they are believed to affect the mind, emotions, and behavior of an individual. But these medications appear to elevate the risk for various birth defects. As a recent study initiated by the University of Copenhagen suggests, the consumption of psychotropic medication ought to be avoided during pregnancy.

Investigators observed the link of psychotropic medications with birth defects. They analyzed the data between 1998 and 2007 regarding Danish children under the age of 17. The study claims that the data highlighted 429 adverse drug reactions in these children. After thorough examinations the authors concluded that more than half of these cases indicated extreme birth defects including birth deformities and severe withdrawal syndromes.

Associate Professor Lisa Aagaard affirmed, “A range of serious side effects such as birth deformities, low birth weight, premature birth, and development of neonatal withdrawal syndrome were reported in children under two years of age, most likely because of the mother’s intake of psychotropic medication during pregnancy.”

In addition, the investigators inspected 4,500 pediatric adverse drug reaction reports and revealed a clear link between psychotropic medications and birth defects. It was ascertained that psychostimulants like Ritalin known to treat attention deficit disorder (ADD) was accountable in 42 percent of unfavorable reactions. And while antidepressants such as Prozac probably caused 31 percent reactions, 21 percent were contributed by antipsychotics similar to Haldol.

Read entire article: http://www.healthjockey.com/2010/06/28/birth-defects-appear-due-to-intake-of-psychotropic-medications-during-pregnancy/

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Study shows antidepressants cause major increase in miscarriages (68%) yet pregnant women still being targeted for usage

cchrint — Thu, 24 Jun 2010 18:07:25 +0000

Before It’s News
June 23, 2010

This study comes on the heels of ones showing these drugs cause birth defects. But even now, regulatory agencies aren’t taking action.

Medical powers-that-be are pressing to identify women “at risk” of depression during pregnancy—likely to push them into taking anti-depressants. Now, a study has shown that SSRI and SNRI antidepressants can increase miscarriages by 68 percent. These drugs have also been associated with birth defects. Now, that is truly depressing.

A study published in the online edition of the Canadian Medical Association Journal reported a 68% increase in miscarriages in women who take modern antidepressants. Paroxetine, the SSRI sold as Paxil or Seroxat, and venlafaxine, the SNRI sold as Effexor, were especially risky, and taking more than one antidepressant was also particularly dangerous.

As previously documented in Babies of Women Taking Antidepressants Born With Deformities, Dr. Anick Bérard, PhD, one of the study’s authors, has also noted that antidepressants have been associated with birth defects. It shouldn’t, of course, come as any surprise that an agent guilty of causing birth defects would also result in miscarriages.

Overall, antidepressant use was found to increase the risk of miscarriage by 68%. Paroxetine increased the risk by 75% and venlafaxine more than doubled the risk to a 110% greater chance of spontaneous abortion.

In comparison, the increased risk of miscarriage due to untreated depression is 19 percent.

It’s obvious that increased miscarriage risks of 68 percent, 75 percent, and 110% with SSRI and SNRI treatment make a 19 percent increase in untreated pregnancy depression pale by comparison.

Read entire article: http://beforeitsnews.com/news/84/868/Antidepressants_Cause_Major_Increase_in_Miscarriages.html

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CCHR International » Pregnancy

Paxil and Prozac Linked to Risk of Heart Birth Defects

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