Posts Tagged ‘polypharmacy’

“How do I get off all the depression drugs?” We asked an expert

Thursday, June 30th, 2011
Foodconsumer.org
By Martha Rosenberg

Phillip Sinaikin, MD, is a Florida psychiatrist who has been in practice for 25 years. Author of “Get Smart About Weight Control” and co-author of “Fat Madness: How to Stop the Diet Cycle and Achieve Permanent Well-Being,” his new book focuses on excesses and industry influence in the field of psychiatry.

Rosenberg: Your new book, Psychiatryland, traces how deception, conflicts of interest, medical enabling and direct-to-consumer advertising have resulted in millions being on psychiatric drugs they don’t need. One patient you describe has legitimate mourning and grief work to do after his wife leaves him for his own cousin. But his grief is pathologized into “bipolar disorder” by the system, including his own mother.

Sinaikin: By the time I saw this patient, he was on Wellbutrin and another antidepressant, the mood stabilizers Eskaltih and Keppra, the antipyschotic Abilify, the tranquilizer Klonopin and Adderall for ADD. Calling grief a psychiatric disorder deflates and dishonors the spiritual dimension of loss and grief and the sadness which is a marker of the lost love. By the time this patient came under my care (three years after the loss of his wife) his “case” had become such a jumbled, incomprehensible and irrational mess of overdiagnosis and overmedication that the only word I can use to describe it is CRIMINAL.

Rosenberg: Can you explain the popularity of such drug cocktails? The drugs haven’t been tested together so the patient is a guinea pig. And their total cost can exceed $1000 per month, often shuttled onto taxpayers because the people are considered disabled under federal entitlement programs.

Sinaikin: Psychiatry mimics science but is not a real science. The symptoms it treats are subjective and have not been demonstrated and cannot be demonstrated at the cellular level. That gives psychiatrists free reign to just experiment and symptom chase, often insanely chasing the side effects and negative interactions of the current drug regimen with more and more drugs. Polypharmacy is also a way psychiatrists can distinguish themselves in an increasingly competitive market. No one believes you need a specialist for one drug — any primary care physician can give you Zoloft — but for multi-drug therapy you do. If you don’t write a prescription as a psychiatrist, you won’t work these days. It is like being a pacifist and having no choice but working in a bullet factory.

Rosenberg: A lot of this trial-and error polypharmacy is buttressed by the concept of “treatment resistance” and “Prozac poop-out.”

Sinaikin: I write in the book that an antidepressant not working anymore is no different than getting used to anything that used to thrill us. We buy our dream house with two bedrooms and a garage and after a while it doesn’t make us happy anymore and we are eyeing the house with three bedrooms and a pool. Another example, of course, is falling in and out of love.

Rosenberg: You document in Psychiatryland the creation of new diseases to sell drugs including adults now diagnosed with childhood disorders like ADD and children with adult disorders like bipolar and depression.

Sinaikin: One scientific article I read about the new childhood disorders sounds like a satire. Two well-respected “thought leaders” in psychiatry were debating the underlying pathology of a three-year-old girl who ran out in traffic. The first doctor believed her dangerous behavior was indicative of an Oppositional-Defiant disorder. The other doctor argued her impulsive act represented grandiose delusions where this girl believed she was special and cars could not harm her. She was, therefore, bipolar.

Rosenberg: Another shocker in your book is how everyday drug and alcohol addicts were recast as having psychiatric conditions for money.

Sinaikin: The insurance companies told the rehabs they would no longer pay for inpatient rehab for heroin, cocaine or alcohol unless there was also another Axis 1 psychiatric disorder like bipolar disorder or major depression. I was working in a drug treatment facility when the change happened. Since addicts typically complain of anxiety and depression, a completely understandable emotional response to their toxic lifestyles, it was “no problem” to add a new label and throw a few psychiatric drugs at their now relabeled “dual diagnosis.”  Of course the central tenet of recovery, taking personal responsibility, was buried by the new victim narrative of self-medicating a previously undiagnosed mental illness.

Rosenberg: Treating addiction with psychiatric drugs before or instead of seeking a higher power is antithetical to the 12 Steps of Alcoholics Anonymous.

Sinaikin: As I say throughout my book, human beings are indescribably complex. There are times when the dual-diagnosis concept is necessary and helpful but clearly not applicable to 100% of the cases of addiction as it is now applied. I believe that the 12 Step model is an ideal model of recovery. Patients can have the help whenever they are truly ready, not just when someone decides to foist it on them. Most importantly, the addicts helping other addicts are doing it to facilitate their own recovery and not for ulterior motives such as money. Amazingly, in a world gone profit crazy 12 Step recovery programs are still free. I conceptualize the 12 Steps as a distillation of the spiritual principles world’s great religions but no one is forced to believe in anything including God.

Rosenberg: Given conflicts of interest at the American Psychiatric Association, which drives psychiatric diagnoses, in the FDA drug approval process itself and the legions of doctors willing to huckster for pharma as thought leaders or Key Opinion Leaders (KOLs), do you see any hope of rescuing people from Psychiatryland?

Sinaikin: The system is unbelievably bad and even worse than it looks. But, I think a goal that could be achieved would be a repeal of direct-to-consumer advertising. Patients now come into my office asking me if they have ADD or bipolar disorder or if they can have Cymbalta. When I began practicing psychiatry, long before direct-to-consumer advertising, this would never have happened.

Psychiatryland

Author: Phillip Sinaikin, MD
978-1-4502-5290-4 (pbk),
978-1-4502-5289-8 (cloth)
978-1-4502-5288-1 (ebk)

Publisher: I Universe
Published Year: 2010
available online at
Amazon and Barnes & Noble

http://www.foodconsumer.org/newsite/Shopping/Books/depression_drugs_0629110547.html

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Long Awaited Army Report on Suicides Ignores Role of Suicide-Causing Drugs such as Antidepressants/Antipsychotics

Monday, August 2nd, 2010

OpEdNews
By Martha Rosenberg
August 1, 2010

Why are troops killing themselves?

The long awaited Army report, “Health Promotion, Risk Reduction, Suicide Prevention” considers the economy, the stress of nine years of war, family dislocations, repeated moves, repeated deployments, troops’ risk-taking personalities, waived entrance standards and many aspects of Army culture.

What it barely considers is the suicide-inked antidepressants, antipsychotics and antiseizure drugs whose use exactly parallels the increase in US troop suicides since 2005.

In the report Chief of Staff General Peter W. Chiarelli acknowledges antidepressant risks, saying there’s “fair quality evidence that second generation antidepressants (mostly SSRI) increase suicidal behavior in adults aged 18 to 29 years” but adds that “other research evidence shows the benefit of antidepressant use”.

And nowhere does he acknowledge the suicide potential of antiseizure drugs so widely used for pain and as “mood stabilizers” by troops even though the FDA mandated suicide warnings on Lyrica, Topamaz, Depakote, Lamictal, Tegretol, Depakene, Klonopin and 16 others in 2008.

(Lamictal also has the distinction of wasting more taxpayer money than any other drug according to a July American Enterprise Institute report. Medicaid spent an unnecessary $51 million on Lamictal instead of buying a generic last year, thanks to GSK salesmen. You go, guys,)

When asked by NPR’s Robert Siegel if the high number of medicated troops contributed to suicide, Gen. Chiarelli said, “The good thing about those numbers is…the prescriptions were all made by a doctor.” Asked why troops who had not even deployed were among the suicides, Chiarelli said there were other stressors involved.

In June Marine Times reported 32 deaths on prescription drugs in Warrior Transition Units (WTUs) since 2007 and said an internal review “found the biggest risk factor may be putting a soldier on numerous drugs simultaneously, a practice known as polypharmacy.”

But instead of citing dangerous drugs and drug cocktails for turning troops suicidal (and accident prone and at risk of death from unsafe combinations) the Army report cites troops’ illicit use of them along with street drugs. (The word “illicit” appears 150 times in the Army report and “psychiatrist” appears twice.)

No, it’s not the 8,000 urine samples in 2009 which showed prescription drug traces according to the Army report — it’s the fact that 21 percent of the drugs were “illicit.”

No wonder the revised suicide report form suggested by the Army report doesn’t even have a box to enter “adverse reactions to drug or drug combinations.” Instead, it has a box that asks how long before a suicide a patient was “compliant” with the prescription. Was the medication “taken as prescribed? Skipped?” Taken “In excess of prescription? In different manner (e.g., crushed instead of in capsule)?”

Read entire article here:  http://www.opednews.com/articles/Army-Suicide-Report-Ignore-by-Martha-Rosenberg-100801-596.html?show=votes

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Freedom of Information Act request made to Pentagon officials regarding alarming drug overdoses in our armed forces

Monday, June 7th, 2010

Air Force Times
By Andrew Tilghman and Brendan McGarry
June 6, 2010

Prescription drug cocktails have lead to at least 32 accidental overdoses among Marines and soldiers since 2007, bringing military medical practices for treating physical and psychiatric problems under scrutiny.

At least 30 soldiers and two Marines overdosed while under the care of Army Warrior Transition Units or the Marine Corps Wounded Warrior Regiment, created three years ago to tightly focus care and attention on troops suffering from injuries as a result of combat.

Most of the troops had been prescribed “drug cocktails,” combinations of drugs including painkillers, sleeping pills, antidepressants and anti-anxiety drugs, interviews and records show. In all cases, suicide was ruled out.

Army officials say the deaths are often complicated by troops mixing medications with alcohol, taking their own medications incorrectly or without a prescription.

It is unclear how many troops across the entire military have died from drug toxicity. Pentagon officials have not provided information about accidental drug deaths across the military despite a Military Times Freedom of Information Act request submitted nearly two months ago. Data on military deaths is compiled by the Armed Forces Institute of Pathology and maintained at the Pentagon’s Defense Manpower Data Center.

The Army deaths have shocked that service’s medical community and prompted an internal review. But despite a “safety stand down” in January 2009, the number of fatalities continued to rise last year — to 15 in 2009, up from 11 the year before. Meanwhile the total number of soldiers assigned to the 29 WTUs nationwide dropped from about 12,000 to about 9,000.

The internal review found the biggest risk factor may be putting a soldier on numerous drugs simultaneously, a practice known as polypharmacy. According to an Army analysis from June 2009, about 9 percent of WTU patients — 800 soldiers — were prescribed a combination of drugs that included pain, psychiatric and sleep medications.

As a result, the Army medical community has begun to question the widespread practice of polypharmacy and has quietly overhauled the way it prescribes, distributes and monitors the riskiest drugs.

Read entire article:  http://www.airforcetimes.com/news/2010/06/military_drug_deaths_060710w/

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Psychiatry’s Growing Practice of Multiple Prescriptions: 60% of patients drugged were given multiple prescriptions

Tuesday, January 5th, 2010

John Gever
MedPage Today
January 4, 2010

Psychiatrists who prescribe drugs for their patients today usually give more than one at a time, often with little scientific basis, researchers said.

About 60% of patients with psychiatrist office visits leading to a drug prescription received at least two medications in 2005-2006, according to government survey data analyzed by Ramin Mojtabai, MD, PhD, MPH, of Johns Hopkins University, and Mark Olfson, MD, MPH, of Columbia University.

That was up from about 43% in 1996-1997 (P<0.001), the researchers reported in the January Archives of General Psychiatry.

They also found that 33% of prescription-associated visits led to three or more medications in the latter period, compared with 17% nine years earlier (P<0.001).

These multiple combinations sometimes involved drugs within the same class — two or more antidepressants for depressed patients, for example — but more often drugs of different classes.

Gaining in popularity during the study period were combinations of antidepressants and antipsychotic drugs, with an adjusted odds ratio of 1.96 (P<0.001) for each year during the study period.

Read entire article: http://www.medpagetoday.com/Psychiatry/GeneralPsychiatry/17785

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