Posts Tagged ‘Paxil’

Drugged to Death: Soldiers returning from war are being given deadly cocktails of psychiatric drugs

Tuesday, March 9th, 2010

AlterNet
By Martha Rosenberg
March 9, 2010

Sgt. Eric Layne’s death was not pretty.

A few months after starting a drug regimen combining the antidepressant Paxil, the mood stabilizer Klonopin and a controversial anti-psychotic drug manufactured by pharmaceutical giant AstraZeneca, Seroquel, the Iraq war veteran was “suffering from incontinence, severe depression [and] continuous headaches,” according to his widow, Janette Layne.

Soon he had tremors. ” … [H]is breathing was labored [and] he had developed sleep apnea,” Layne said.

Janette Layne, who served in the National Guard during Operation Iraqi Freedom along with her husband, told the story of his decline last year, at official FDA hearings on new approvals for Seroquel. On the last day of his life, she testified, Eric stayed in the bathroom nearly all night battling acute urinary retention (an inability to urinate). He died while his family slept.

Sgt. Layne had just returned from a seven-week inpatient program at the VA Medical Center in Cincinnati where he was being treated for post-traumatic stress disorder (PTSD). A video shot during that time, played by his wife at the FDA hearings, shows a dangerously sedated figure barely able to talk.

Sgt. Layne was not the first veteran to die after being prescribed medical cocktails including Seroquel for PTSD.

Read entire article:  http://www.alternet.org/world/145892/are_veterans_being_given_deadly_cocktails_to_treat_ptsd

« Return to news items


  • Share/Bookmark

Ghostwriting 101: Pharma hires firms to write glowing reviews of a drug, then pays docs to sign off as authors

Thursday, March 4th, 2010

Scoop Independent News
By Evelyn Pringle
March 4, 2010

A month before the first Paxil birth defect trial against GlaxoSmithKline was set to begin, the Associated Press ran the headline, “Glaxo Used Ghostwriting Program to Promote Paxil,” in reporting on a program called “CASPPER,” which allowed doctors to “take credit for medical journal articles mainly written by company consultants.”

“Drug companies frequently hire outside firms to draft a manuscript touting a company’s drug, retain a physician to sign off as the author and then find a publisher to unwittingly publish the work,” the Associated Press said on August 19, 2009. “Drug company salespeople often present medical journal articles to physicians as independent proof that their drugs are safe and effective.”

Between 2000 and 2002, articles from the CASPPER program appeared in five medical journals. On August 21, 2009, Jim Edwards on BNET, described the CASSPER ghostwriting brochure. The document shows that the intent of CASSPER was to flood the market with ghostwritten information, he said. It stated: “Paxil Product Management has budgeted for 50 articles for 2000.”

The trial in Kilker v Glaxo ended on October 13, 2009, with a jury in Philadelphia finding that Glaxo “negligently failed to warn” the doctor treating Lyam Kilker’s mother about Paxil’s risks and the drug was a “factual cause” of Lyam’s heart defects. The family was award $2.5 million.

Read entire article:  http://www.scoop.co.nz/stories/HL1003/S00045.htm

« Return to news items


  • Share/Bookmark

Congressional Hearings Held On Antidepressant-Induced Suicide In The Military

Wednesday, March 3rd, 2010

The Huffington Post
By Peter Breggin
March 3, 2010

On February 24, 2010 the Veterans’ Affairs Committee of the U. S. House of Representatives chaired by Bob Filner (D-CA) held hearings on “Exploring the Relationship Between Medication and Veteran Suicide.” Military suicides have risen rapidly in recent years at the same time that the prescription of antidepressants and other psychiatric drugs has escalated. The hearing focused on the dangers of the newer antidepressants like Prozac, Paxil, Zoloft, Celexa, Lexapro, Cymbalta, and Effexor.

Starting in the early 1990s, I was the first psychiatrist to write and speak extensively about the newer antidepressants causing suicide, violence, and mania. It was gratifying when Rep. Filner decided to hold the hearings after reading my new book, Medication Madness: The Role of Psychiatric Drugs in Cases of Violence, Suicide and Crime (2008) and called me as his lead witness. I presented scientific evidence that antidepressants cause suicide, violence and mania. I also emphasized the profound danger of prescribing drugs that cause impulsivity, hostility and suicidality to heavily armed young men and women under stress on active military duty. I recommended that the armed services curtail the use of these drugs and rely instead on psychotherapeutic and educational processes that have already proved effective. I also called for additional research in the military and the VA concerning suicide and violence caused by antidepressants.

There is scant evidence for the effectiveness of antidepressants, and overwhelming evidence for their harmfulness. The military is already moving toward the implementation of better educational programs to help active duty soldiers handle stress. These educational programs, and counseling, need to replace the use of psychiatric drugs.

Read entire article:  http://www.huffingtonpost.com/dr-peter-breggin/congressional-hearings-on_b_480613.html

« Return to news items


  • Share/Bookmark

Paxil Birth Defect Litigation – 600 Cases Pending

Wednesday, February 17th, 2010

Scoop Independent News
By Evelyn Pringle
February 18, 2010

GlaxoSmithKline has paid out close to $1 billion to resolve lawsuits involving Paxil since the drug came on the market in 1992, according to a December 14, 2009 Bloomberg report. But the billion dollars does not cover the more than 600 Paxil birth defect cases currently pending in multi-litigation in Pennsylvania.

Glaxo has settled about 10 birth defect cases, according to Sean Tracey, a Houston attorney who represented the family of a child victim in the first jury trial that decided in favor of the plaintiff on October 13, 2009, Bloomberg reports. The settlements in those lawsuits averaged about $4 million, people familiar with the cases told the new service.

First Trial A Bust for Glaxo

The first trial, in the case of Kilker v Glaxo, ended with a jury in Philadelphia finding that Glaxo “negligently failed to warn” the doctor treating Lyam Kilker’s mother about Paxil’s risks and the drug was a “factual cause” of Lyam’s heart defects. The jury awarded the family $2.5 million in compensatory damages.

After the trial, juror Joe Mellon told Bloomberg that Glaxo did not conduct adequate studies on Paxil. “There were a couple of what I thought were safety signals and what the plaintiffs presented as safety signals that they should have maybe looked into further,” he said.

On October 14, 2009, the American Lawyer reported that the plaintiff’s lead attorney, Sean Tracey, had quizzed the jurors about what swayed their decision. “They said the fact that GSK never adequately studied their own drug was a big deal,” Tracey said. “The animal testing they did showed that they had a potential problem, and they didn’t follow up with adequate studies on animals or humans.”

Read entire article:  http://www.scoop.co.nz/stories/HL1002/S00128.htm

« Return to news items


  • Share/Bookmark

In addition to causing birth defects & preterm labor—new study says antidepressants cause breastfeeding problems

Thursday, January 28th, 2010

AttorneyAtLaw.com
January 27, 2010

Taking Prozac, Paxil, or other antidepressants from the class of drugs called selective serotonin reuptake inhibitors (SSRIs) can cause delays in lactation in new mothers and difficulty in breast-feeding newborns, a new study says.

Researchers from the University of Cincinnati found SSRIs can result in delayed secretory activation after giving birth. SSRIs regulate the hormone serotonin in the body to stave off depression, but the hormone also is crucial to the breasts’ ability to deliver milk when it is needed, the study’s authors said.

A delay in breast milk production caused by taking SSRIs can “impact serotonin regulation in the breast, placing new mothers at greater risk of a delay in the establishment of a full milk supply,” the study found.

The study’s findings are troubling because millions of people take Prozac, Paxil, and other brands of SSRIs to treat a variety of depression-related disorders. Paxil and other SSRI drugs have been linked before to other serious health complications, including heart-related birth defects and pre-term labor.

Read entire article:  http://www.attorneyatlaw.com/2010/01/prozac-and-paxil-can-cause-breast-feeding-problems-new-study-says/

« Return to news items


  • Share/Bookmark

Daily Mail – “Internal bleeding. Strokes. Birth defects. The long term effects of antidepressants are terrifying”

Tuesday, January 12th, 2010

Jane Feinmann
The Daily Mail
January 12, 2010

Just a few years ago, Yasmin Miller would have been horrified by the suggestion she might take antidepressants for the rest of her life. But today, the 37-year-old can barely imagine a future without this daily chemical boost.

Yasmin’s ‘perfect’ life as a corporate tax adviser was shattered when, in 2003, she developed severe depression. Although incapacitated by the illness, she needed convincing that a pill could make a difference.

‘I was gobsmacked when my GP suggested antidepressants, because I thought they were addictive,’ she recalls. ‘But now I’ve changed my mind: depression is just like epilepsy or diabetes or any other illness where you need to take a daily pill for life in order to stay healthy.’

Just 20 years after the launch of the ’sunshine drug’ Prozac, Yasmin is one of hundreds of thousands of young women who can’t imagine life without antidepressants.

But some experts are warning of disturbing parallels with the ‘mother’s little helper’ scandal of the Seventies and Eighties, when thousands of women became addicted to widely prescribed tranquillisers, including Valium.

Read entire article: http://www.dailymail.co.uk/health/article-1242502/Hooked-happy-pills-Internal-bleeding-Strokes-Birth-defects-The-long-term-effects-antidepressants-terrifying.html

« Return to news items


  • Share/Bookmark

Psychology Today “Five Reasons not to take SSRIs: Now that SSRIs don’t work for depression, don’t take them!”

Friday, January 8th, 2010

Lennard Davis
Psychology Today
January 7, 2010

For the past five years, and in my recent book OBSESSION: A HISTORY, I have been questioning the effectiveness of Prozac-like drugs known as SSRIs. I’ve pointed out that when the drugs first came out in the early 1990’s there was a wildly enthusiastic uptake in the prescribing of such drugs. Doctors were jubilantly claiming that the drugs were 80-90 per cent effective in treating depression and related conditions like OCD. In the last few years those success rates have been going down, with the NY Times pointing out that the initial numbers had been inflated by drug companies suppressing the studies that were less encouraging. But few if any doctors or patients were willing to hear anything disparaging said about these “wonder” drugs.

Now the tune has changed.

Reason One: A study in the Journal of the American Medical Association says that SSRI’s like Paxil and Prozac are no more effective in treating depression than a placebo pill. That means they are 33 per cent effective, which is the percent of patients who will respond well to a sugar pill. The article goes on to say that although SSRI’s are effective to some degree in treating severe depression they don’t have any effect on the routine type of depressions they are most often used to treat. The take-home message is–don’t take SSRI’s if you have normal, mild, or routine depression. It’s a waste of money, and the drugs have serious side-effects including loss of sexual drive.

Reason Two: A January 4 article in MedPage Today cites a study done at Columbia University and Johns Hopkins.  The study says that doctors routinely prescribe not one but two or three SSRI’s and other psychopharmological drugs in combination with few if any serious studies to back up the multiple usage.

Read entire article: http://www.psychologytoday.com/blog/obsessively-yours/201001/five-reasons-not-take-ssris

« Return to news items


  • Share/Bookmark

Antidepressant no more effective than sugar pills in treating depression

Tuesday, January 5th, 2010

Andrew Stern
Reuters
January 5, 2010

Mild to severe depression might be better treated with alternatives to antidepressant drugs, which do not help patients much more than an inactive placebo, researchers said Tuesday.

Combining data from six studies that examined the effectiveness of two commonly prescribed antidepressants — paroxetine and imipramine — found the drugs produced benefits only slightly greater than a placebo in patients with mild to severe depression.

“They would have done just as well or just about as well with a placebo,” said Robert DeRubeis, a psychologist at the University of Pennsylvania, Philadelphia, who with colleagues performed the meta-analysis.

Paroxetine is one of a popular class of drugs, selective serotonin reuptake inhibitors, and is sold under the brand name Paxil by GlaxoSmithKline. Imipramine is an older tricyclic antidepressant drug developed in the 1950s.

The so-called placebo effect is powerful in treating depression, where people believe they are h

« Return to news items


  • Share/Bookmark

Before you take that antidepressant, visit website feauturing 3,500 crimes/suicides related to antidepressant use

Monday, January 4th, 2010

Martha Rosenberg
OpEdNews.com
January 3, 2010

With our national love of drugs, sex, celebrities and violence you’d think SSRIstories.com would be more popular.

The 12-year-old web site lists 3,500 crime related news reports linked to the use of SSRI antidepressants with celebrities like Wynona Ryder, Heath Ledger, Brittany Murphy, Anna Nicole Smith, Heather Locklear, Glen Campbell, Carrie Fisher, Sharon Osbourne, Phil Hartman, Princess Di’s driver, Patrick Swayze’s Sister, O.J. Simpson and the Crown Prince of Nepal generously sprinkled in.

You can search and sort stories by drug–Lexapro, Celexa, Luvox, Prozac, Zoloft and Paxil and the related Effexor and Cymbalta–date, location, type of violence and the articles about school shootings, famous cases and legal cases won on SSRI defenses are color coded.

You don’t even have to read the whole article.

SSRIstories founder and manager Betty Henderson pulls out and boldfaces the story’s drug-related citation like Lynyrd Skynyrd harmonicist Mike Caruso’s remark that, “the doctor put me on Cymbalta. That turned me manic,” and Oklahoma murder suspect Ronson Bush’s remark, “I killed my friend when I took these. I’m not going to take them,” when offered SSRIs at the Grady County Jail.

Read entire article: http://www.opednews.com/articles/Before-You-Take-That-Antid-by-Martha-Rosenberg-100103-313.html

« Return to news items


  • Share/Bookmark

Paxil birth defect settlement tops list of “most impactful” lawsuit settlements for 2009

Tuesday, December 15th, 2009

Kristine B.
LawyersandSettlements.com
December 15, 2009

We’re in the countdown to year-end and looking over some of the more impactful settlements LawyersAndSettlements.com has covered over the past year. When we’re talking impactful, everyone around here has an opinion—so we had to throw in some criteria. To get the nod for impact, a settlement had to be one of two things: 1. High dollar value; or 2. Precedent-setting—or at least have the potential to influence similar cases to follow. (Sounds simple, but you try getting Stephen, John, Jaime, Michelle and Ben to settle in on just 7 settlements with just those criteria…) So here we go…7 game-changing settlements for ‘09…

1) Family takes on GlaxoSmithKline

Michelle David filed a lawsuit against GlaxoSmithKline, alleging the company’s antidepressant, Paxil was responsible for her son’s birth defects. David said she had taken Paxil while pregnant and was not aware of the potential side effects. GlaxoSmithKline said that birth defects occur in between three and five percent of all live births, regardless of Paxil use.

Read entire article: http://www.lawyersandsettlements.com/blog/7-game-changing-settlements-of-2009-02165.html

« Return to news items


  • Share/Bookmark