Posts Tagged ‘miscarriage’

Prescription Drug Epidemic Spreads to Babies

Friday, July 16th, 2010

St. Petersburg Times
By Richard Martin
July 16, 2010

Dr. Mary Newport sees the symptoms more and more in the babies she treats: oddly stiff limbs, severe tremors, vomiting, diarrhea, insomnia, crying that never stops.

The common denominator: Their mothers were taking prescription drugs, mostly painkillers like OxyContin and Vicodin, and antianxiety drugs like Xanax during pregnancy.

Some of the moms had no idea these medications would hurt their developing babies — after all, it’s not like it’s heroin or cocaine, many think.

“They are seriously misinformed,” said Newport, medical director of Spring Hill Regional Hospital’s neonatal intensive care unit.

The prescription drug epidemic, well documented among teens and adults, now is claiming victims before they are even born. Tampa Bay area doctors and addiction specialists are reporting a dramatic increase in the number of pregnant addicts and infants needing treatment for withdrawal from prescription drugs.

The trend is reminiscent of the “crack baby” epidemic of the 1980s, when mothers used crack cocaine during their pregnancies.

But area neonatologists say that in some ways, the current trend is worse. Some women don’t understand that prescription drugs can be dangerous during pregnancy. Others decide to stop the drugs as soon as they learn they are pregnant, causing sudden withdrawal that can lead to miscarriage.

And doctors say that treating a baby with drugs like oxycodone, methadone or Xanax in the system takes longer, and involves more medication, than treatment for heroin or cocaine.

“Babies are suffering more,” said Dr. Terri Ashmeade, medical director of Tampa General Hospital’s neonatal intensive care unit. “Withdrawal patterns seem to be worse (with prescription drugs) than what we were seeing with heroin.”

Note from CCHR Int: To see for yourself what psychiatric drug reactions for infants and babies have been reported to the U.S. FDA’s medwatch system (by doctors, pharmacists, consumers etc),  go to our decrypted Medwatch reports: Under the drop down menu for DRUG NAME/DRUG CLASS, scroll all the way down to the bottom until you see CLASS OF DRUGS such as ATYPICAL ANTIPSYCHOTICS or ANTIDEPRESSANTS or STIMULANTS and select one of those.   In the AGE RANGE drop down menu select 0-1 year old then click GENERATE REPORT.   You can do this for each class of psychiatric drug.  And consider this,   by the FDA’s own admission, only 1-10% of side effects are ever reported, so the actual side effects occurring in the general population are much higher.

Click here for Decrypted Medwatch Reports http://www.cchrint.org/psychdrugdangers/medwatch_psych_drug_adverse_reactions.php

Click her to read the rest of the article:  http://www.tampabay.com/news/health/article1109348.ece

« Return to news items


Share

Lawyers & Settlements—Mom Alert: Would you want a 68% Higher Risk of Miscarriage? (Antidepressants & Pregnancy study)

Thursday, June 3rd, 2010

Lawyers & Settlements
By LucyC
June 2, 2010

A new study out yesterday—June 1, 2010—has revealed a higher rate of miscarriages in women who were taking antidepressants during pregnancy. How much higher? Sixty-eight percent—yes —that’s 68%—higher. Frankly, that is nothing short of shocking.

Published in the Canadian Medical Association Journal, the study was done in Canada through the University of Montreal. FYI—This was no small study either—the investigators used data from 5,124 women who are part of a large, population-based study of pregnant women who had clinically verified miscarriages, and a large sample of women from the same registry who did not have a miscarriage. Among the women who miscarried, 284 or 5.5 percent, had taken antidepressants during their pregnancy.

In fact the findings are so robust that the physicians who did the study are suggesting that this is a class effect—in other words the effect could be attributed to all selective serotonin reuptake inhibitors—or SSRIs. Here’s what’s being reported in the press:

“These results, which suggest an overall class effect of selective serotonin reuptake inhibitors, are highly robust given the large number of users studied,” the study’s senior author, Dr. Anick Berard, said in a statement. (UPI.com)

The antidepressants that showed a particular association with miscarriage in the study were paroxetine (trade names: Seroxat and Paxil) and venlafaxine (trade names: Effexor, Efexor, Alventa, Argofan, Trevilor). The investigators also found that the risk of miscarriage doubled with a combination of different antidepressants.

Just for the record, the antidepressants “investigated” in the University of Montreal study are serotonin reuptake inhibitors (citalopram, fluoxetine, fluvoxa-mine, paroxetine and sertraline); tricyclic antidepressants (ami-triptyline, clomipramine, desipramine, doxepin, imipramine, nortriptyline, trimipramine), serotonin– norepinephrine reuptake inhibitors (venlafaxine) and “other antidepressants” (serotonin modulators, monoamine oxidase inhibitors, tetracyclic piperazino-azepines, and dopamine and norepinephrine reuptake inhibitors).

This study is just the latest to show an association between, well, for lack of a better term let’s say “serious adverse events” and SSRIs and SNRIs in particular.

Read entire article:  http://www.lawyersandsettlements.com/blog/mom-alert-would-you-want-a-68-higher-risk-of-miscarriage-03819.html

« Return to news items


Share

New Study—Taking Antidepressants While Pregnant More Than Doubles Risk of Miscarriage

Tuesday, June 1st, 2010

Los Angeles Times
By Thomas H. Maugh II
May 31, 2010

Taking antidepressants during pregnancy increases the risk of spontaneous abortions by about two-thirds, Canadian researchers reported Monday. The increased risk was greatest with the family of drugs known as selective serotonin reuptake inhibitors (SSRIs), especially paroxetine and venlafaxine, and when more than one family of drugs were used.

Depression in women is most common during the child-bearing years, and estimates suggest that as many as 15% of pregnant women suffer from it. Because of fears about the effects of drugs, particularly psychiatric drugs, during pregnancy, only about 3.7% of women use them during the first trimester. Most studies looking at the use of antidepressants during pregnancy have focused on their effects on the fetus. Small studies of their effects on abortion have produced inconsistent results. Expecting mothers cannot routinely stop using the drugs, however, because that also presents risks to both the mother and the fetus.

Producing a controlled clinical trial examining the effects of the drugs is virtually impossible because few women would be willing to participate, experts said. The only way to get at the data is to examine it retrospectively.

In the new study, Dr. Anick Berard, director of the University of Montreal’s Research Unit on Medications and Pregnancy at University Hospital Center Sainte-Justine used information from the Quebec Pregnancy Registry to identify 5,124 women who had a spontaneous abortions between 1998 and 2003 — before warnings about the risks of the drugs became more common — and compared them with about 10 times that many carefully matched women who did not have abortions. A separate database provided information about prescriptions the women had filled.

Read entire article:  http://latimesblogs.latimes.com/booster_shots/2010/05/antidepressants-during-pregnancy-increase-risk-of-sponaneous-abortion-study-finds.html

« Return to news items


Share