Posts Tagged ‘military’

Treatment for PTSD may be killing veterans

Wednesday, September 1st, 2010

War in Context

by News Source on August 31, 2010

Associated Press reports:

Andrew White returned from a nine-month tour in Iraq beset with signs of post-traumatic stress disorder: insomnia, nightmares, constant restlessness. Doctors tried to ease his symptoms using three psychiatric drugs, including a potent anti-psychotic called Seroquel.

Thousands of soldiers suffering from PTSD have received the same medication over the last nine years, helping to make Seroquel one of the Veteran Affairs Department’s top drug expenditures and the No. 5 best-selling drug in the nation.

Several soldiers and veterans have died while taking the pills, raising concerns among some military families that the government is not being up front about the drug’s risks. They want Congress to investigate.

In White’s case, the nightmares persisted. So doctors recommended progressively larger doses of Seroquel. At one point, the 23-year-old Marine corporal was prescribed more than 1,600 milligrams per day — more than double the maximum dose recommended for schizophrenia patients.

A short time later, White died in his sleep.

“He was told if he had trouble sleeping he could take another (Seroquel) pill,” said his father, Stan White, a retired high school principal.

Activist, Vince Boehm, communicated with the Whites and told Beyond Meds:

Stan and Shirley White lost two sons to war. Robert White, a staff sergeant, was killed in Afghanistan in 2005, when his Humvee was hit by a rocket-propelled grenade. But the death of Robert’s younger brother Andrew, who survived Iraq only to succumb to a different battle, is in some ways “harder to accept” says his father.

Struggling with PTSD compounded by grief over the death of his brother, Andrew sought help from VA doctors. Their first line of defense was to prescribe him 20 mg of Paxil, 4 mg of Klonopin and 50 mg of Seroquel. These medications helped at first, but later proved ineffective. Instead of changing the course of treatment, the doctors responded by continually increasing his dosage until the Seroquel alone reached a whopping 1600 mg per day. Within weeks of Andrew’s death, three more young West Virginia veterans died while being treated for PTSD with the same drugs, prompting Stan and Shirley White to begin a mission to find out what the deaths have in common.

Earlier this year, Martha Rosenberg reported on the same deadly cocktail being used to treat PTSD:

Sgt. Eric Layne’s death was not pretty.

A few months after starting a drug regimen combining the antidepressant Paxil, the mood stabilizer Klonopin and a controversial anti-psychotic drug manufactured by pharmaceutical giant AstraZeneca, Seroquel, the Iraq war veteran was “suffering from incontinence, severe depression [and] continuous headaches,” according to his widow, Janette Layne.

Soon he had tremors. ” … [H]is breathing was labored [and] he had developed sleep apnea,” Layne said.

Janette Layne, who served in the National Guard during Operation Iraqi Freedom along with her husband, told the story of his decline last year, at official FDA hearings on new approvals for Seroquel. On the last day of his life, she testified, Eric stayed in the bathroom nearly all night battling acute urinary retention (an inability to urinate). He died while his family slept.

Sgt. Layne had just returned from a seven-week inpatient program at the VA Medical Center in Cincinnati where he was being treated for post-traumatic stress disorder (PTSD). A video shot during that time, played by his wife at the FDA hearings, shows a dangerously sedated figure barely able to talk.

Sgt. Layne was not the first veteran to die after being prescribed medical cocktails including Seroquel for PTSD.

Read the rest of this article here: http://warincontext.org/2010/08/31/treatment-for-ptsd-may-be-killing-veterans/

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Overmedication contributes to military suicides, advocates say

Thursday, August 12th, 2010
By Veronica Nett
The Charleston Gazette

CHARLESTON, W.Va. — The suicide rate among military veterans has ballooned in recent years, in part because of overmedication of service members and a lack of support for veterans, advocates for treatment of Post Traumatic Stress Disorder said Thursday.

Psychiatrists sometimes prescribe drugs as a cure without an actual understanding of what the drugs do, said Dr. Peter R. Breggin, a psychiatrist and author from Ithaca, N.Y.

In 2008, the Army’s suicide rate — 20.2 per 100,000 — exceeded the civilian suicide rate for the first time. The civilian suicide rate has held steady for years at about 18 per 100,000, according to the U.S. Department of Defense.

Breggin and seven panelists addressed a crowd of about 50 therapists, social workers, members of the state Veterans Affairs department, in addition to service members and their families at the 2010 PTSD and Traumatic Brain Injury Education and Awareness Conference.

Care-Net, a branch of the state Council of Churches, sponsored the conference at the Blessed John XXIII Pastoral Center in Charleston.

PTSD is the brain’s natural reaction to extreme stress and traumatizing experiences, said Breggin, the conference’s keynote speaker. Tramuatic brain injury looks just like PTSD, he said.

“There is no drug that improves the function of the brain,” said Breggin, who said he will not prescribe psychiatric drugs as treatment for any disorder.

Psychiatric drugs, such as antidepressants and anxiety medication, alter the chemical balance in the brain, disrupt the release of serotonin and, in many cases, have the same effect as street drugs, Breggin said.

Patients using psychiatric drugs have experienced psychotic and violent behavior, attempted suicide and are unable to think clearly, Breggin said.

Mary Lahas talked about her son, Michael, who she said stuck IV needles into his arms in a suicide attempt.

Her son, an Army infantry member, survived roadside bomb explosions, and witnessed the shooting death of civilians in Iraq, Lahas said Thursday.

He returned from his first deployment in 2008 with PTSD and TBI and suffered from headaches, anxiety, guilt, tinnitus and memory problems, Lahas said. He refused to seek help, she said, because he saw other soldiers ridiculed who did.

When he finally did seek help, he was given a “cocktail of death,” that included antidepressants, anxiety medications and sleep aids, Lahas said.

“He was so overmedicated he could not care for himself — eat, sleep or brush his teeth,” she said.

The drugs and stress led him to try to take his own life, and while standing in his bathroom bleeding, he drew a smiley face on the wall in his own blood, she said.

Read the rest of this article here: http://wvgazette.com/News/201008120975

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Psychiatric drug use skyrockets in U.S. military

Monday, July 26th, 2010

Natural News
By David Gutierrez
July 26, 2010

Use of prescription psychotropics has skyrocketed among U.S. military personnel in recent years, according to an investigation by Military Times.

At least 17 percent of active-duty military personnel are currently taking an antidepressant, including as many as 6 percent of all deployed troops. In contrast, the rate of antidepressant use in the wider U.S. public is only 10 percent.

Overall, one in six military service members takes at least one type of psychiatric drug. The numbers are probably higher than estimated, since troops are also known to share and trade prescription drugs with each other, even while in combat zones.

Data obtained from the Defense Logistics Agency show that overall use of psychiatric drugs increased by 76 percent between 2001 and 2009. More specifically, use of anti-seizure drugs increased 70 percent, use of sedatives and anxiety drugs increased 170 percent, and antipsychotic use increased 200 percent.

Spending on anticonvulsants increased from $16 million to $35 million per year, spending on anxiety drugs and sedatives increased from $6 million to $17 million, and spending on antipsychotics increased from $4 million to $16 million.

Although antidepressants are among the drugs most commonly taken by military personnel, their use increased only 40 percent between 2001 and 2009. Spending actually dropped by 16 percent, likely reflecting the new availability of less-expensive generic drugs.

According to a 2009 study by the Veterans Affairs Administration, approximately 60 percent of psychiatric drug use by military personnel is for “off-label” uses not approved by the FDA. Thus, antipsychotic drugs intended for the treatment of schizophrenia are now being widely prescribed for post-traumatic stress disorder symptoms such as anger, headaches, nervousness and nightmares.

“Patients may be exposed to drugs that have problematic side effects without deriving any benefit,” said Robert Rosenheck of Yale University. “We just don’t know. There haven’t been very many studies.”

Further compounding concern over side effects, many troops regularly mix two or more drugs together into untested cocktails. The effects of multiple drugs acting in unison have rarely been tested. When both drugs act on the same organ — in this case, the brain — the chance of unforeseen interactions is even greater.

“In the case of poly-drug use — the ‘cocktail’ — where you are combining an antidepressant, an anticonvulsant, an antipsychotic, and maybe a stimulant to keep this guy awake — that has never been tested,” Breggin said.

Among the side effects that some health professionals worry about are impaired motor skills, reduced reaction time, increased suicide risk, irritability, aggressiveness and hostility.

“Imagine causing that in men and women who are heavily armed and under a great deal of stress,” psychiatrist Peter Breggin said.

Read entire article:  http://www.naturalnews.com/029285_psychiatric_drugs_military.html

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Chantix & Violence: What Patients Have In Common

Thursday, July 22nd, 2010

Pharmalot
By Ed Silverman
July 22, 2010

For the past three years, the Chantix smoking cessation pill has caused a stir after being associated with suicidal behavior and vivid dreams (see here and here). Consequently, the government banned the Pfizer drug for pilots and licenses wouldn’t be issued to truck drivers taking the med (see this). The FDA subsequently imposed a risk management program and Pfizer added warnings.

Now, a new study in The Annals of Pharmacotherapy finds Chantix is not only associated with violent and agressive thoughts and acts, but has also identified some of the common characteristics among people using the pill and their subsequent behavior. The drug “does have warnings about psychiatric side effects, but it skims over aggression/violence towards others to focus mainly on suicidal behaviors,” says Thomas Moore, one of the co-authors and a senior scientist at the Institute for Safe Medication Practices, a non-profit that has issued reports previously about Chantix side effects.

“We believe this may be the first scientific report to examine the characteristics of aggression/violence as a psychiatric side effect for any prescription drug. What do these cases look like? A question answered for possibly the first time. We found the details striking and chilling. This is the first time we know of that aggression/violence has been clearly documented as a side effect in a peer reviewed scientific journal. This raises the question of whether (Chantix) is suitable for use in the military, by police and others who are already in stress situations. One key characteristic of these events is uncontrollable rage. Not a good side effect for people paid to carry guns.”

The researchers obtained 78 adverse event reports from the FDA MedWatch database containing medical terms describing possible acts or thoughts of aggression/violence; four more cases came from clinical trials, and three others came from published literature. Ultimately, they used 26 case reports for study and these described 10 events with assault, nine cases of homicidal ideation and seven instances of other thoughts or acts of aggression/violence. They noted that the patient population was predominantly middle-aged women, but “an unlikely age group and sex for assault and acts of violence toward others.”

“In all 26 cases,” they write, “the acts or thoughts of violence appeared to be inexplicable and unprovoked. A woman struck her 17-year-old daughter in the mouth while the daughter was driving a car, with a young granddaughter also present. A 42-year-old man punched a stranger at a bowling alley. The stranger and two friends responded and knocked out the subject’s front teeth. A 24-year-old female started beating her boyfriend in bed because he “looked so peaceful” and she later attempted suicide. A 29-year-old female struck an acquaintance twice in the face, and then started smashing doors in her own home and beating on her truck.”

Read entire article:  http://www.pharmalot.com/2010/07/chantix-and-violence-what-patients-have-in-common/

*The package insert for Chantix shows that it contains a type of chemical compound that is better known as benzodiazepine—benzodiazepines are otherwise known as anti-anxiety drugs.

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Freedom of Information Act request made to Pentagon officials regarding alarming drug overdoses in our armed forces

Monday, June 7th, 2010

Air Force Times
By Andrew Tilghman and Brendan McGarry
June 6, 2010

Prescription drug cocktails have lead to at least 32 accidental overdoses among Marines and soldiers since 2007, bringing military medical practices for treating physical and psychiatric problems under scrutiny.

At least 30 soldiers and two Marines overdosed while under the care of Army Warrior Transition Units or the Marine Corps Wounded Warrior Regiment, created three years ago to tightly focus care and attention on troops suffering from injuries as a result of combat.

Most of the troops had been prescribed “drug cocktails,” combinations of drugs including painkillers, sleeping pills, antidepressants and anti-anxiety drugs, interviews and records show. In all cases, suicide was ruled out.

Army officials say the deaths are often complicated by troops mixing medications with alcohol, taking their own medications incorrectly or without a prescription.

It is unclear how many troops across the entire military have died from drug toxicity. Pentagon officials have not provided information about accidental drug deaths across the military despite a Military Times Freedom of Information Act request submitted nearly two months ago. Data on military deaths is compiled by the Armed Forces Institute of Pathology and maintained at the Pentagon’s Defense Manpower Data Center.

The Army deaths have shocked that service’s medical community and prompted an internal review. But despite a “safety stand down” in January 2009, the number of fatalities continued to rise last year — to 15 in 2009, up from 11 the year before. Meanwhile the total number of soldiers assigned to the 29 WTUs nationwide dropped from about 12,000 to about 9,000.

The internal review found the biggest risk factor may be putting a soldier on numerous drugs simultaneously, a practice known as polypharmacy. According to an Army analysis from June 2009, about 9 percent of WTU patients — 800 soldiers — were prescribed a combination of drugs that included pain, psychiatric and sleep medications.

As a result, the Army medical community has begun to question the widespread practice of polypharmacy and has quietly overhauled the way it prescribes, distributes and monitors the riskiest drugs.

Read entire article:  http://www.airforcetimes.com/news/2010/06/military_drug_deaths_060710w/

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Memorial Day 2010: Psychiatric drugs triggering deaths of U.S. soldiers treated for PTSD

Wednesday, May 26th, 2010

Examiner.com
By Jed Shlackman
May 26, 2010

Andrew Tighman, writing in the Marine Corps Times, recently described the investigation of Fred A. Baughman Jr., M.D. into the deaths of military personnel taking multiple psychotropic medications. Baughman was alerted to a series of soldier deaths upon reading a May 2008 article in the Charleston [WV] Gazette titled “Vets Taking Post Traumatic Stress Disorder Drugs Die in Sleep.” Baughman, a retired neurologist known previously for his criticism of medication treatments of ADHD and other mental health disorders, suspected that the reported cases could be part of a much larger problem. In the cases of four West Virginia veterans who died in their sleep in 2008 Baughman found that the deaths were not due to overdoses. The veterans were apparently normal upon going to bed, yet all died in their sleep after taking a combination of prescribed medications that included Paxil, Seroquel, and Klonopin. Each case involved a sudden cardiac incident and resulting death.  This adds to growing concern about serious adverse effects of psychiatric medications commonly prescribed to emotionally disturbed or traumatized soldiers.

Research reported by Ray, et. al in the January 2009 New England Journal of Medicine noted that antipsychotic drugs doubled the risk of sudden cardiac death, while another study disclosed in March 2009 by Whang, et. al. found that antidepressant drugs also increase the rate of sudden cardiac death. A literature review of studies from 2000-2007 titled “Sudden Cardiac Death Secondary to Antidepressant and Antipsychotic Drugs” published in Expert Opinion on Drug Safety; 2008, No. 2, March 2008, pp. 181-191(14), found that “Antipsychotics can increase cardiac risk even at low doses, whereas antidepressants do it generally at high doses or in the setting of drug combinations.” In an Army Times article by Gina Cavallaro in February 2009 it was reported that more than 70 soldiers assigned to the Army’s warrior transition units had died, with at least 50% of the deaths attributed to natural causes that included a high number of cardiac deaths.

In one case investigated by Baughman an Army private was found dead in his barracks at Ft. Carson, Colorado, with sudden cardiac death reported by EMTs on the scene followed later by the death being re-classified as a suicide. Baughman suspects that there is an attempt to cover up the dangers of these psychiatric drugs, as the U.S. military, doctors, and drug manufacturers could be held accountable if it became apparent that these dangerous drug combinations are being used despite published evidence of the hazards.

Read entire article:  http://www.examiner.com/x-12517-Miami-Holistic-Health-Examiner~y2010m5d26-Memorial-Day-2010-Psychiatric-drugs-triggering-deaths-of-US-soldiers-treated-for-PTSD

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Earth Times: Neurologist Fred Baughman—Vets Sudden Deaths Due to Antidepressant & Antipsychotic Drugs

Monday, May 24th, 2010

EarthTimes.org
By Fred A. Baughman, Jr.
May 24, 2010

Fred A. Baughman Jr., MD today announced the results of his research into the “series” of veterans’ deaths acknowledged by the Surgeon General of the Army.

Upon reading the May 24, 2008, Charleston (WV) Gazette article “Vets Taking Post Traumatic Stress Disorder Drugs Die in Sleep,” Baughman began to investigate why these reported deaths were “different.”  And, why they were likely, the “tip of an iceberg.”

Andrew White, Eric Layne, Nicholas Endicott and Derek Johnson were four West Virginia veterans who died in their sleep in early 2008. Baughman’s research suggests that they did not commit suicide and did not “overdose” leading to coma as suggested by the military.  All were diagnosed with PTSD.  All seemed “normal” when they went to bed.  And, all were on Seroquel (an antipsychotic) Paxil (an antidepressant) and Klonopin (a benzodiazepine).

They were not comatose and unarousable ? with pulse and respirations or pulse intact, responsive to CPR, surviving transport to a hospital, frequently surviving.  These were sudden cardiac deaths.

At the time, Stan White, father of Andrew White knew of eight such cases in Kentucky, Ohio and West Virginia.

In a February 7, 2008 interview with the Chicago Tribune, Lt. Gen. Eric B. Schoomaker, the Army’s surgeon general, said there has been “a series, a sequence of deaths” in the new “warrior transition units.”

In April 2005, the FDA warned that Seroquel put elderly patients with dementia-related psychosis at increased risk of death.

On January 15, 2009, Ray et al, reported that antipsychotics double the risk of sudden cardiac death.  On March 17, 2009, Whang et al reported that antidepressants, as well, increase the rate of sudden cardiac deaths.

And yet, in an August 14, 2008 analysis of two of the four Charleston-area deaths, the Inspector General for Veterans Affairs concluded (Report No. 08-01377-185): “Although antipsychotic medications have been identified as possible causes of cardiac rhythm disturbances, a 2001 review…found no association with olanzapine (Zyprexa), quetiapine (Seroquel), or risperidone (Risperdal) and Torsades de Pointes (a fatal heart rhythm) or sudden death… we are unaware of any clinical practice guidelines recommending baseline or periodic electrocardiogram monitoring in young, healthy patients on quetiapine (Seroquel).”

However, in a literature review covering the years 2000-2007, entitled Sudden Cardiac Death Secondary to Antidepressant and Antipsychotic Drugs: [Expert Opinion on Drug Safety; 2008, Number 2, March 2008 , pp. 181-194(14)] Sicouri and Antzelevitch conclude: (1) “A number of antipsychotic and antidepressant drugs can increase the risk of ventricular arrhythmias and sudden cardiac death?” (2) “Antipsychotics can increase cardiac risk even at low doses whereas antidepressants do it generally at high doses or in the setting of drug combinations,” and (3) “These observations call for?an ECG at baseline and after drug administration.”

Read entire article:  http://www.earthtimes.org/articles/show/fred-a-baughman-jr-md,1312839.shtml

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Medicating the Military—76% increase in psychiatric drugs; one in six now on a psychiatric drug or drug cocktail

Wednesday, March 17th, 2010

Army Times
By Andrew Tilghman and Brendan McGarry
March 17, 2010

At least one in six service members is on some form of psychiatric drug.

And many troops are taking more than one kind, mixing several pills in daily “cocktails” — for example, an antidepressant with an antipsychotic to prevent nightmares, plus an anti-epileptic to reduce headaches — despite minimal clinical research testing such combinations.

The drugs come with serious side effects: They can impair motor skills, reduce reaction times and generally make a war fighter less effective. Some double the risk for suicide, prompting doctors — and Congress — to question whether these drugs are connected to the rising rate of military suicides.

“It’s really a large-scale experiment. We are experimenting with changing people’s cognition and behavior,” said Dr. Grace Jackson, a former Navy psychiatrist.

A Military Times investigation of electronic records obtained from the Defense Logistics Agency shows DLA spent $1.1 billion on common psychiatric and pain medications from 2001 to 2009. It also shows that use of psychiatric medications has increased dramatically — about 76 percent overall, with some drug types more than doubling — since the start of the current wars.

Read entire article:  http://www.armytimes.com/news/2010/03/military_psychiatric_drugs_031710w/

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In wake of shootings: Read what psychiatrist Peter Breggin said about psych drugs/military/violence & drug withdrawal

Saturday, November 7th, 2009

Dr. Peter Breggin
The Huffington Post
June 20, 2009

Here are the starting facts: Death by suicide is at record levels in the armed services. Simultaneously the use of antidepressant drugs is also at record levels, including brand names like Prozac, Zoloft, Paxil, Celexa and Lexapro. According to the army, in 2007 17% of combat troops in Afghanistan were taking prescription antidepressants or sleeping pills. Inside sources have given me an even bleaker picture: During Vietnam, a mere 1% our troops were taking prescribed psychiatric drugs. By contrast, in the past year one-third of marines in combat zones were taking psychiatric drugs.

Are the pills helping? The army confirms that since 2002 the number of suicide attempts has increased six-fold. And more than 128 soldiers killed themselves last year.

One theory states that the increased prescription of drugs is a response to increased depression among the soldiers. In reality, the use of psychiatric drugs escalates when, and only when, drug companies and their minions target new markets. In this case, the armed services have been pushing drugs as a cheap alternative to taking genuine care of the young men and women in our military. Instead of shortening tours of duty, instead of temporarily removing stressed-out soldiers from combat zones, and instead of providing counseling–the new army policy is to drug the troops.

Read entire article: http://www.huffingtonpost.com/dr-peter-breggin/antidepressants-cause-sui_b_218465.html

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Before psychiatrists start vying for more $ to drug troops ask: Was Fort Hood, Texas shooter part of our medicated army?

Thursday, November 5th, 2009

Mark Thompson
TIME
June 5, 2008

Seven months after Sergeant Christopher LeJeune started scouting Baghdad’s dangerous roads — acting as bait to lure insurgents into the open so his Army unit could kill them — he found himself growing increasingly despondent. “We’d been doing some heavy missions, and things were starting to bother me,” LeJeune says. His unit had been protecting Iraqi police stations targeted by rocket-propelled grenades, hunting down mortars hidden in dark Baghdad basements and cleaning up its own messes. He recalls the order his unit got after a nighttime firefight to roll back out and collect the enemy dead. When LeJeune and his buddies arrived, they discovered that some of the bodies were still alive. “You don’t always know who the bad guys are,” he says. “When you search someone’s house, you have it built up in your mind that these guys are terrorists, but when you go in, there’s little bitty tiny shoes and toys on the floor — things like that started affecting me a lot more than I thought they would.”

So LeJeune visited a military doctor in Iraq, who, after a quick session, diagnosed depression. The doctor sent him back to war armed with the antidepressant Zoloft and the antianxiety drug clonazepam. “It’s not easy for soldiers to admit the problems that they’re having over there for a variety of reasons,” LeJeune says. “If they do admit it, then the only solution given is pills.”

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