Posts Tagged ‘Marketing’

How Mental Disorders are Manufactured & Marketed “Not in the Mood? You Could Have Hypoactive Sexual Desire Disorder”

Wednesday, May 19th, 2010

U.S. News & World Report
Deborah Kotz
May 19, 2010

Not interested in sex? Perhaps you have a condition called hypoactive sexual desire disorder, caused by a brain chemical imbalance. That’s the message conveyed in a new “educational campaign” launched last week by the Society of Women’s Health Research with actress Lisa Rinna as a celebrity spokesperson talking about “the brain’s potential role in desire.” On the campaign’s new website, you might conclude that if you’re not fantasizing about sex a lot you should definitely talk to your doctor.

You won’t, though, learn about any medications for HSDD—because there are no approved drugs for it. A new drug, called flibanserin, may be approved by the Food and Drug Administration after its advisory committee meets to discuss the drug next month. In the meantime, flibanserin manufacturer Boehringer-Ingelheim has funded an HSDD educational campaign to create demand for the drug, some experts say. And, yes, Rinna is a paid spokesperson.

“It’s like priming the market,” says Lisa Schwartz, an associate professor of medicine at the Dartmouth Institute for Health Policy and Clinical Practice in Lebanon, N.H. “Disease awareness is a very important part of [preparing for] an upcoming ad campaign” for any new drug—which will no doubt occur if and when flibanserin is approved. (I previously reported on the over-medicalization of low sexual desire in women.)

Unfortunately, the website doesn’t provide much useful information about the low sex drive condition, which was first identified in the 1970s and is included in the psychiatric bible, the Diagnostic and Statistical Manual of Mental Disorder. You wouldn’t learn from the website, for example, that certain medications—including antidepressants, birth control pills and antihypertensives—can dampen your sex drive. Nor would you learn about the usefulness of psychological treatments like psychotherapy or mindfulness training. And the website doesn’t differentiate between “situational” HSDD, caused by lifestyle factors like lack of sleep, breastfeeding, stress, and relationship issues, and “generalized” HSDD, which may arise from some sort or physiological problem, like low testosterone levels or a brain chemical imbalance. In this interview with Fox News, Rinna said she lost her sex drive soon after her second child was born, which, according to experts, means she probably had some explainable reason like excess fatigue or low sex hormones due to nursing.

Read entire article: http://health.usnews.com/health-news/family-health/brain-and-behavior/articles/2010/05/19/not-in-the-mood-you-could-have-hypoactive-sexual-desire-disorder.html

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This is a good start: FDA Wants Docs to Help Identify Misleading Drug Ads with New “Bad Ad” Program

Tuesday, May 11th, 2010

Pharmalot
By Ed Silverman
May 11, 2010

If you’re a doctor, the FDA wants your help in identifying ‘bad’ advertisements for prescription drugs. Seriously. The agency is calling it’s new ‘Bad Ad’ program an educational outreach effort and, not surprisingly, it’s being run by DDMAC, the agency’s Division of Drug Marketing, Advertising, and Communications, which issues all those warning letters and violations.

The goal of the program is to “help health care providers recognize misleading prescription drug promotion and provide them with an easy way to report this activity to the agency,” DDMAC director Tom Abrams says in a statement. Usually, the FDA finds ‘bad ads’ by reviewing promotional materials submitted for agency review, fielding complaints (often one company sniping at another) and scouring medical conventions. But Abrams acknowledges the FDA has limited ability to monitor promotional activities that occur “in private.”

Read entire article:  http://www.pharmalot.com/2010/05/fda-to-docs-tell-us-about-bad-drug-ads/

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Feds say drug company’s illegal payments to doctors fueled antipsychotic drugs wrongly prescribed to kids

Friday, May 7th, 2010

Seattle Post-Intelligencer
May 6, 2010

AstraZeneca Pharmaceuticals LP will pay Washington state nearly $10 million for improperly marketing Seroquel, a drug used to treat schizophrenia and manic depression.

Federal and state officials say that AstraZeneca illegally paid for doctors to attend meetings at resorts, where those doctors would “advise” the drug maker about marketing messages for unapproved uses. Medical professionals were also paid to serve as authors of promotional articles and to conduct studies for unapproved uses of the drug.

An investigation shows that as a result of these activities, misleading information was distributed about Seroquel, reports the state Attorney General’s Office. This led health providers to wrongly prescribe the drug to children, adolescents, and dementia patients in long-term care facilities – costing publicly funded programs millions of dollars.

Seroquel and other drugs are purchased for recipients of Medicaid, a government program for low-income consumers. Seroquel is approved for the treatment of schizophrenia, bipolar disorder, also known as manic depression, and other conditions.

A government investigation showed that between Jan.1, 2001, through Dec. 31, 2006, the drug was wrongly promoted to treat aggression, Alzheimer’s, anger management, anxiety, attention-deficit hyperactivity disorder, dementia, and sleeplessness. Sequoel isn’t approved by the Food and Drug Administration to treat these conditions.

Read entire article:  http://blog.seattlepi.com/boomerconsumer/archives/204984.asp

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Psychiatry’s latest mental disorders—”Creativity? There’s a pill for that. Not to mention nonconformity and quirkiness”

Tuesday, April 27th, 2010

Not to mention nonconformity and quirkiness — the definition of mental illness changes

Canada.com
By Sharon Kirkey
April 27, 2010

Since 1950, man has landed on the moon, made computers commonplace and harnessed nuclear power.

We’re obviously using our minds to the fullest. Yet the number of ways we can go officially crazy has nearly tripled.

The hugely influential reference book used by psychiatrists and other mental health professionals the world over to diagnose mental illness — the Diagnostic and Statistical Manual of Mental Disorders — currently lists 357 types of psychiatric afflictions, up from 128 when the first volume was published in 1952.

The psychiatric establishment says it has learned to detect more mental illness in the population than was possible a half-century ago, and that science has advanced to the point that the broadly defined disorders of the past are now seen with much greater resolution, yielding many more specific conditions.

We’re not expanding the domain, they argue, as much as we’re refining it.

But skeptics say it is less about advances in brain science and more about psychiatry shuffling more and more behaviours and reactions to life’s letdowns into boxes of mental dysfunction and assigning them codes, and that we risk becoming so overdiagnosed and overmedicated, we’ll be like the patient in The New Yorker cartoon, who asks his psychiatrist: “Could we up the dosage? I still have feelings.”

“The unavoidable conclusion is that we’ve narrowed healthy behaviour so dramatically that our quirks and eccentricities — the normal emotional range of adolescence and adulthood — have become problems we fear and expect drugs to fix,” says Christopher Lane, author of Shyness: How Normal Behavior Became a Sickness.

It’s not enough that people sometimes want to be alone, Lane says. Solitude? According to the DSM, including its criteria for “avoidant” and “schizoid”personality disorders, that could be viewed as a sign of mild psychosis, he warns. Feeling restless, keyed up or on edge could be markers of generalized anxiety disorder, and trouble sleeping a symptom of a major depressive disorder.

The more diagnostic categories added to the DSM, the more broadly they’re defined, the bigger the market of potential new drug customers grows, says Stuart Kirk, professor of social welfare at the University of California Los Angeles School of Public Affairs. Within each revision of psychiatry’s bible, pharmaceutical companies see a “bonanza” of marketing possibilities, he says.

Read entire article:  http://www.canada.com/life/Creativity+There+pill+that/2955948/story.html

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New York Magazine: Shrink Revolt—The controversy over psychiatric diagnoses and the DSM continues

Monday, April 26th, 2010

New York Magazine
By Jennifer Senior
April 25, 2010

Two Jews may, as the saying goes, have three opinions, but that appears to be a fairly modest ratio when compared with psychiatrists. It was inevitable that revisions to the Diagnostic and Statistical Manual of Mental Disorders would invite controversy—it’s the classic reference work for mental-health professionals, and a convenient field guide to understanding crazy exes for the rest of us—but even the American Psychiatric Association, which first appointed the work groups to update the text two years ago, couldn’t have predicted the squabbles now under way. Dr. Allen Frances, the man who chaired the task force that created the current edition (the DSM-IV), has today emerged as the most trenchant, and relentless, critic of the proposed revisions to the upcoming edition (the DSM-5; among the changes is a transition to Arabic numerals). Last Tuesday was the final day those revisions were open to public comment. “And hopefully,” Frances says, “most of them will drop out.”

Basically, Frances believes that the first draft of the DSM-5 is too promiscuous with its labels, both by loosening diagnostic criteria and by introducing a host of new and, to his mind, problematic maladies—like Binge Eating Disorder (more or less defined as gorging on massive amounts at least once a week for three months). By the estimate of one DSM-5 task-force member, Frances says, this disorder already afflicts 6 percent of the population. “And that,” he notes, “is before drug companies start marketing something for it.”

As Frances pointed out in a recent Los Angeles Times editorial, such taxonomic adjustments only seem to further shrink “the ever-shrinking domain of the normal.” Take another DSM-5 proposed addition: Temper Dysregulation Disorder With Dysphoria. Frances fears this may be deployed for kids who have typical temper problems. Or Major Depressive Episode: As it’s redefined, it could now be used to describe someone who’s spent two weeks grieving over a lost spouse, he contends. But the worst offender, in Frances’s view, is Psychosis Risk Syndrome, which attempts to identify and treat youngsters before they become psychotic. In his view, there isn’t any evidence that early intervention with medication helps, while there’s plenty to suggest that many teens could be misidentified. “And that I saw as a public-health danger,” he says, “because there are real drawbacks to being on antipsychotics.” Like weight gain and diabetes. “Those children are also disproportionately on Medicaid,” he adds.

Read entire article:  http://nymag.com/news/intelligencer/65632/

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Internal documents show drug company marketed their antipsychotic Risperdal for unapproved usage on elderly & kids

Wednesday, March 10th, 2010

Bloomberg.com
By Margaret Cronin Fisk, Jef Feeley and David Voreacos
March 10, 2010

Johnson & Johnson made plans to reach $302 million in geriatric sales for its antipsychotic Risperdal just months after federal regulators said the company falsely claimed the drug was safe and effective with the elderly, according to internal documents.

The U.S. Food and Drug Administration told J&J in 1999 that its marketing materials for geriatric patients overstated Risperdal’s benefits and minimized risks. A J&J business plan for the next year called for increasing the drug’s market share for elderly dementia sales, an unapproved use, according to newly unsealed documents in a lawsuit by the state of Louisiana.

“The geriatric market represents Risperdal’s second wave of growth,” J&J officials wrote in the business plan. “The aging population will continue to drive market growth well into the next century.”

Louisiana officials cited the document and dozens of other internal J&J files in its lawsuit claiming the company marketed Risperdal to the elderly and children for unapproved uses. Professor Jerry Avorn of Harvard Medical School, who isn’t involved in the case, called the papers “one of the more egregious examples” of marketing drugs to vulnerable patients.

“By 2010, most grownups in medicine know that drug companies resort to unsavory practices to promote drugs, but seeing such clear evidence in black and white of the details of a campaign like this is still pretty upsetting,” Avorn said.

Read entire article:  http://www.bloomberg.com/apps/news?pid=20601109&sid=ag4Ya8UOIob0&pos=13

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Psychiatrists want ‘binge eating’ as official mental disorder-millions of overweight Americans could be profitable target

Sunday, November 22nd, 2009

Melissa Healy
Los Angeles Times
November 23, 2009

Rina Silverman’s refrigerator is almost always empty. She keeps it that way to avert episodes of frantic food consumption, often at night after a full meal, in which she tastes nothing and feels nothing but can polish off a party-sized bag of chips or a container of ice cream, maybe a whole box of cereal. The food she’s eating at these moments hardly matters.

In short order, the nothing that Silverman feels and tastes will give way to nauseating fullness, and a bitter backwash of guilt, shame and self-reproach.

The fullness, in time, passes. But the corrosive shame and self-reproach are always there.

Silverman, a 43-year-old executive assistant from Sherman Oaks, is one of the 145 million Americans who are overweight or obese. But the frenzies of consumption put her in a far smaller category of Americans, not all of whom are even overweight.

Silverman is a binge eater, one who is slowly inching her way toward recovery. She and as many as 1 in 30 Americans — roughly 7.3 million adults — are at the center of a psychiatric debate over whether and how to recognize binge eating as a mental disorder.

Read entire article: http://www.latimes.com/features/health/la-he-binge23-2009nov23,0,2869829.story

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Pharma’s Drug Ads: From Million Dollar TV Ads to $1.7 Billion Internet Marketing Campaign

Monday, November 16th, 2009

November 16, 2009

On November 13th, 2009, Pharmaceutical companies flocked to a two-day FDA hearing into online drug advertising, which could influence their use of social media on the net. 1 Already, the explosive growth in online advertising has intensified public concerns: the pharmaceutical industry spent more than $1 billion on Internet ads last year and is projected to spend $1.7 billion on such marketing efforts in 2012, according to the Direct Marketing Association.2

Both Eli Lilly and Merck have received warning letters this year from the FDA accusing them of misleading online advertisements.3 But while the FDA scrambles to monitor online ads, who monitors the psychiatric-pharmaceutical industry’s use of front groups to indirectly market their products?

A Washington Post article of June 16, 2009 reported that an increasing number of pharmaceutical firms are turning to social media tools, such as Facebook, YouTube, Twitter and MySpace, to market their products.  It cites how a community site sponsored by drugmaker McNeil called “ADHD Allies”—aimed at adults with ADHD—was established and offered an online podcast on financial advice and an “ADHD self-assessment tool.”4

British psychiatrist Joanne Moncrieff explains how this ultimately increases drug sales because only a biomedical approach is promoted: “Drug companies…provide funds for pro drug patient and carer groups and address advertising or disease promotion campaigns to the general public…This influence has helped to create and reinforce a narrow biological approach to the explanation and treatment of mental disorders and has led to the exclusion of alternative” treatments.5

Such websites do not mention company’s product but rather market the “disease.” In advertising, it can be accomplished through a strategy known as “condition branding,” where “mental illness” can be pitched just like cars, beer or laundry detergent.  Witness the brand name “bipolar” and “social anxiety disorder” that drug companies marketed at a fever pitch.

John Read, PhD, Psychology Department, University of Auckland did an analysis of 54 random “advocacy” groups for Post Traumatic Stress Disorder (PTSD) through the Internet. The results, published in the Journal of Trauma & Dissociation this year, found 42% of the websites received drug company funding. The researchers found:

  • “Patients tend to trust these organizations to act in an unbiased manner” but as earlier researchers argued in some cases “patient organizations have become a mouthpiece for the pharmaceutical industry in influencing regulatory authorities.”
  • “Drug company influence within the area of mental health is prevalent and now extends to the Internet. This influence is not always transparent. This study suggests that drug company sponsorship of websites leads to a greater emphasis on pharmacology in the treatment of PTSD,” Dr. Read’s report concludes.6

ADHD Allies/ADHD Moms

In June 2008 Concerta was given an expanded indication by FDA and is now indicated for patients aged 6 to 65.7 In July 2008, McNeill Pediatrics—a subsidiary of Ortho-McNeill Pharmaceuticals—launched what they called an “unbranded group” called “ADHD Moms.” ADHD Moms markets the trademarked name “Mom-bassadors” to get mothers into the Facebook page. 8

  • McNeill spuriously claims “the group is not product-specific, nor are there any advertisements for the company’s ADHD drug Concerta (methylphenidate).” Well not directly, but providing material for the site is a Dr. Quinn, a paid consultant and speaker for McNeil Pediatrics. 9 April White, who also provides content is a paid spokesperson for McNeil Pediatrics.10
  • On April 22 2009, McNeill launched a second ADHD-focused Facebook page called “ADHD Allies,” this time targeting adults.  The “Allies” are board members of another front group Attention Deficit Disorder Association (ADDA), funded by McNeill.11
  • The pharmaceutical company has trademarked “ADHD Allies” and “ADHD Moms.”  ADHD Allies was responsible for a “2008 Harris Interactive survey of 1,000 adults with ADHD.” Not surprisingly, the survey found the condition significantly affects them. 12

Log onto The Bipolar Journey: Living With Bipolar Depression website and while it does show AstraZeneca on the home page, there’s no mention of its blockbuster antipsychotic drug Seroquel, approved by the FDA in 2006 for “bipolar.”  The site looks like a patient information site providing facts about the “disease” and misleadingly saying that it may be caused by a chemical imbalance—for which there is no evidence.

It refers people to the National Alliance for the Mentally Ill (NAMI) that has received $23 million recently from at least 18 drug companies. The site shows that of 17 cites for the exhibit’s showing in 2009, 12 are conferences or events put on by NAMI.

It also links to The Depression and Bipolar Support Alliance, a group that received close to $1 million in pharmaceutical company funding in 2007.

According to an August 27 2009 press announcement, AstraZeneca launched its interactive exhibit, endorsed by New York psychiatrist Janet Taylor. The press release does not mention that Dr. Taylor has financial ties to the company.13

In 2005, global sales for Seroquel reached $2.8 billion.  October 20, 2006, company announced Seroquel was FDA approved for bipolar.14 Within a year, sales reached $3 billion and then soared again in 2008 to $4.66 billion.15

By funding social media front groups that talk only about the “disorder,” drug companies can overcome fears of running afoul of FDA regulations that govern drug advertising and “are embracing social networks to help brand and position their companies in a positive light with consumers and practitioners.”  The top 10 drug companies using social media are: Pfizer, Johnson and Johnson, Novartis, Boehringer Ingelheim, AstraZeneca US, Bayer, GlaxoSmithKline, Sanofi-Aventis, Roche, and Merck.16

This post was written by CCHR International.
Coming next from CCHR Int: Psycho Pharma Front Groups

1 “FDA Addresses Drug Ads in Online Social Media,” Red Orbit, 13 Nov. 2009.

3 “FDA Addresses Drug Ads in Online Social Media,” Red Orbit, 13 Nov. 2009.

5 Joanne Moncrief, in a “Study of the Influence of the Pharmaceutical Industry on Academic and Practical Psychiatry,” http://www.critpsynet.freeuk.com/pharmaceuticalindustry.htm

6 http://www.isst-d.org/jtd/mansell_&_read_ptsd_drug_cos_&_internet%20.pdf; Journal of Trauma & Dissociation, 10:9–23, 2009

12 “Adults ‘Facing’ ADHD: ADHD Allies™ Offers Unique Online Community for Adults with ADHD on New Facebook® Page,” http://multivu.prnewswire.com/mnr/concerta/36533/

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Pharma spends billions marketing to doctors; Eli Lilly paid $22 million in first 3 months of the year

Friday, August 28th, 2009

Kris Hundley
St. Petersburg Times
August 30, 2009

There are lots of reasons why your doctor might switch your prescription to a Lilly drug.

One of them might be found in a new online database that lists how much Eli Lilly & Co. paid physicians for their expertise during the first quarter of 2009.

For the first time, Floridians can see if their doctors juggled patient appointments with speaking gigs for the maker of popular drugs like Cymbalta, Zyprexa and Cialis.

Drug companies spend billions on marketing to doctors because it works: Targeted doctors prescribe more of the company’s products.

Lilly was forced to disclose its physician pay data, which it calls a “faculty registry,” as part of a $1.4-billion settlement with the federal government earlier this year.

Read entire article: http://www.tampabay.com/news/health/medicine/drug-makers-willing-to-pay-to-get-doctors-approval/1031817

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Doped Up and Duped – nearly impossible to find independent studies of psych drugs with no Pharma ties

Monday, August 10th, 2009

David Healy
guardian.co.uk
August 8, 2009

Adverse effects of widely-prescribed drugs are often overlooked because there is so little truly independent academic evidence

Since 2005, the SSRI paroxetine, first marketed by GlaxoSmithKline as Seroxat, has carried warnings of risk of birth defects. In the US litigation in which I have been asked to give evidence, the plaintives will argue that, even before they were launched, there was good laboratory evidence that the SSRIs might cause problems, and, following their initial marketing, evidence emerged over a decade ago from clinical use that the drugs actually do cause problems.

Yet these drugs have been actively promoted, de facto primarily to women of child-bearing years. How could this happen?

Part of the problem is that having gone to their GP with a nervous problem, many women become dependent on a prescribed SSRI and find it impossible to stop using it whether they wish to get pregnant or if they find they are pregnant while on treatment. But few, if any, of these women will have been informed of either the risk of birth defects or the risk of becoming addicted. Why not?

What we are seeing here is the astonishing marketing power of pharmaceutical companies, which can now effect huge changes in medical culture within months. In this case, a great part of the scientific literature (the primary marketing tool of companies) on the use of antidepressants in pregnancy and on dependence on antidepressants is ghostwritten – just as virtually all literature on giving antidepressants to children was, at one point, company-written.

Read entire article: http://www.guardian.co.uk/commentisfree/2009/aug/08/seroxat-pharmaceutical-birth-defect

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