Posts Tagged ‘effexor’

Prescription Pill-Popping By Far a Leading Killer as Florida’s Drug Deaths Spike 20%

Thursday, July 1st, 2010

FlaglerLive.Com
July 1, 2010

Oxycodone, the addictive prescription pain-killer also known by its Purdue Pharma brand name OxyContin, directly caused more deaths in Florida in 2009 than cocaine, heroin and morphine combined. Prescription drugs as a whole are killing far more Floridians than illegal drugs, with some 8,600 deaths last year involving at least one prescription drug, according to an annual report released today by the Florida Medical Examiners Commission.

That’s 5 percent of all deaths in Florida in 2009, when 171,300 people died in the state.

The number of people killed by prescription drugs is a significant 20 percent increase over last year’s 6,200 deaths attributed to overdoses. Much of the increase is due to a spike in oxycodone addiction. The increase in prescription-drug addiction continues a trend that began in Florida 10 years ago, when prescription drugs overtook illegal drugs as leading causes of drug-related deaths.

Alcohol is also included in the examiners’ analysis, and it leads the way of all drug-related deaths, with 4,046.

The annual report is a stark look at the effects of legalized drug addiction and over-prescription of drugs, both of which affect a far larger segment of the population than recreational or illegal narcotics.

For the first time in 2009, the commission tracked deaths by region. In Flagler County’s district, which includes St. Johns and Putnam counties, 22 deaths were attributed to oxycodone (the fourth lowest number in the state’s 23 districts), with 13 of those deaths directly attributed to the drug, and nine cited as being present among other drugs that contributed to death.

Hydrocodone claimed 16 lives in the district. Cocaine contributed to 19 deaths in the Flagler district, though only four cases were directly attributed to the drug. In 15 cases, cocaine was present in the body in conjunction with other drugs that proved lethal. Overall in Florida, cocaine-related deaths (including the majority of cases where cocaine wasn’t directly the factor but was present in the body at the time of death), have fallen from a peak of 2,179 in 2007 to 1,462 in 2009. (Again, cocaine was the direct result of death in 529 cases out of those).

Ken Kramer, a researcher with the Citizens Commission on Human Rights of Florida, says the numbers underestimate the extent of the problem, because medical examiners do not track deaths attributed to antipsychotic drugs or to antidepressants, both of which carry black-box or black-label warnings. The warnings on antidepressants, required by the Food and Drug Administration, state that the drugs increase the risk of suicidal thinking and behavior in children, adolescents and young adults up to age 24. (Antidepressants include Paxil, Prozac, Zoloft, Effexor, Lexapro and Celexa.)

Anti-psychotic drugs carry a variety of black label warnings of increased mortality in elderly patients (including a death rate almost twice as high for people taking Risperdal, for example). Those drugs, prescribed and often overprescribed in nursing homes and assisted living facilities, include Abilify, Clozaril, Geodon, Risperdal, Seroquel and Zyprexa.

“Certainly, the actual number of prescription drug deaths is higher than the annual report states,” Kramer said. “It is unknown just how much higher because the Medical Examiners Commission does not track these classes of drugs.”

Two years ago Kramer got his concern heard by the commission following an email exchange with a commissioner in which he argued that antidepressants and anti-psychotic drugs’ contributions to mortality should be part of the annual report. He was rebuffed. One examiner vsaid he had not seen “more than the occasional death caused by these types of drugs,” according to the minutes of the Aug. 13, 2008 meeting of the commission.

Read entire article:  http://flaglerlive.com/7256/florida-prescription-drugs-deaths-oxycontin-oxycodone

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Study shows antidepressants cause major increase in miscarriages (68%) yet pregnant women still being targeted for usage

Thursday, June 24th, 2010

Before It’s News
June 23, 2010

This study comes on the heels of ones showing these drugs cause birth defects. But even now, regulatory agencies aren’t taking action.

Medical powers-that-be are pressing to identify women “at risk” of depression during pregnancy—likely to push them into taking anti-depressants. Now, a study has shown that SSRI and SNRI antidepressants can increase miscarriages by 68 percent. These drugs have also been associated with birth defects. Now, that is truly depressing.

A study published in the online edition of the Canadian Medical Association Journal reported a 68% increase in miscarriages in women who take modern antidepressants. Paroxetine, the SSRI sold as Paxil or Seroxat, and venlafaxine, the SNRI sold as Effexor, were especially risky, and taking more than one antidepressant was also particularly dangerous.

As previously documented in Babies of Women Taking Antidepressants Born With Deformities, Dr. Anick Bérard, PhD, one of the study’s authors, has also noted that antidepressants have been associated with birth defects. It shouldn’t, of course, come as any surprise that an agent guilty of causing birth defects would also result in miscarriages.

Overall, antidepressant use was found to increase the risk of miscarriage by 68%. Paroxetine increased the risk by 75% and venlafaxine more than doubled the risk to a 110% greater chance of spontaneous abortion.

In comparison, the increased risk of miscarriage due to untreated depression is 19 percent.

It’s obvious that increased miscarriage risks of 68 percent, 75 percent, and 110% with SSRI and SNRI treatment make a 19 percent increase in untreated pregnancy depression pale by comparison.

Read entire article: http://beforeitsnews.com/news/84/868/Antidepressants_Cause_Major_Increase_in_Miscarriages.html

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Lawyers & Settlements—Mom Alert: Would you want a 68% Higher Risk of Miscarriage? (Antidepressants & Pregnancy study)

Thursday, June 3rd, 2010

Lawyers & Settlements
By LucyC
June 2, 2010

A new study out yesterday—June 1, 2010—has revealed a higher rate of miscarriages in women who were taking antidepressants during pregnancy. How much higher? Sixty-eight percent—yes —that’s 68%—higher. Frankly, that is nothing short of shocking.

Published in the Canadian Medical Association Journal, the study was done in Canada through the University of Montreal. FYI—This was no small study either—the investigators used data from 5,124 women who are part of a large, population-based study of pregnant women who had clinically verified miscarriages, and a large sample of women from the same registry who did not have a miscarriage. Among the women who miscarried, 284 or 5.5 percent, had taken antidepressants during their pregnancy.

In fact the findings are so robust that the physicians who did the study are suggesting that this is a class effect—in other words the effect could be attributed to all selective serotonin reuptake inhibitors—or SSRIs. Here’s what’s being reported in the press:

“These results, which suggest an overall class effect of selective serotonin reuptake inhibitors, are highly robust given the large number of users studied,” the study’s senior author, Dr. Anick Berard, said in a statement. (UPI.com)

The antidepressants that showed a particular association with miscarriage in the study were paroxetine (trade names: Seroxat and Paxil) and venlafaxine (trade names: Effexor, Efexor, Alventa, Argofan, Trevilor). The investigators also found that the risk of miscarriage doubled with a combination of different antidepressants.

Just for the record, the antidepressants “investigated” in the University of Montreal study are serotonin reuptake inhibitors (citalopram, fluoxetine, fluvoxa-mine, paroxetine and sertraline); tricyclic antidepressants (ami-triptyline, clomipramine, desipramine, doxepin, imipramine, nortriptyline, trimipramine), serotonin– norepinephrine reuptake inhibitors (venlafaxine) and “other antidepressants” (serotonin modulators, monoamine oxidase inhibitors, tetracyclic piperazino-azepines, and dopamine and norepinephrine reuptake inhibitors).

This study is just the latest to show an association between, well, for lack of a better term let’s say “serious adverse events” and SSRIs and SNRIs in particular.

Read entire article:  http://www.lawyersandsettlements.com/blog/mom-alert-would-you-want-a-68-higher-risk-of-miscarriage-03819.html

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The Huffington Post: “Pilots Taking Antidepressants? The FAA Is Risking Our Lives”

Monday, April 19th, 2010

The Huffington Post
By Peter Breggin
April 19, 2010

A few years ago I was hired by the FAA to defend the agency against a suit brought by a pilot who wanted to fly while taking a prescription antidepressant. I helped the FAA formulate its defense of the agency’s ban on pilots using antidepressants and, as a result, the ban remained in effect. Pilots remained unable to fly while taking antidepressants, including the newer ones such as Prozac, Paxil, Zoloft, Celexa, Lexapro and Effexor.

How times have changed. Ignoring the scientific data on adverse drug effects that the agency and I generated and evaluated for the earlier case, the FAA is lifting its 70-year-old ban on allowing pilots to take antidepressants. Has the science changed–improving the adverse reaction profile of these drugs? To the contrary, since that time my most dire observations have been confirmed in the FDA-approved label for all antidepressants. Now there is not only a Black Box Warning for suicidality in children, youth and young adults, but also a lengthy Warnings section about a variety of extremely dangerous abnormal behavioral reactions in all ages including aggression, hostility, disinhibition, impulsivity and mania. Even when not severe, these reactions impair judgment and increase the likelihood of accidents and violence.

According to the FDA-approved guidelines, prescribers are supposed to give a special Medication Guide to patients and their families that warns about dangerous drug-induced reactions including suicide, violence and a variety of unexpected negative behaviors. Originally intended for children and youth, the Medication Guide is now expanded to cover all age groups, including adults. The Medication Guide for all ages can be found at the conclusion of each FDA-approved label for antidepressant drugs in the 2010 Physicians’ Desk Reference.

Why did the FAA lift the ban on pilots using antidepressants? According to FAA statements to the media, depressed pilots sometimes kept on flying while secretly taking antidepressants. “Our concern is that they haven’t necessarily been candid,” FAA Administrator Randy Babbitt reportedly told the press on a conference call. They were flying below the radar of drug testing, so to speak. The new policy not only allows pilots to use antidepressants, it grants a degree of amnesty to those who have been using them illegally in the past.

The FAA feels it’s safer to allow the use of antidepressants because it will make it easier for pilots to obtain needed treatment for depression. It supposedly will also make it easier to monitor their use of these dangerous drugs. If we accept this argument, why not legalize stimulants such as amphetamine as well? They would help keep the overworked pilots awake. And while the FAA is at it, why not let them use marijuana, since they may be doing it illegally on their own without anyone monitoring them.

Unfortunately, monitoring pilots on antidepressants won’t work nearly as well as might be hoped. Many severe emotional and behavioral reactions occur in the first one to three days of antidepressant dosing, or shortly after dose changes, either up or down–long before the next scheduled appointment. Although close monitoring and informing the family to be on the alert can be helpful, and should be done, it won’t prevent many of the drug reactions that occur abruptly and without warning. In addition, doctors too often fail to warn the patient and the family about the risks. As a medical expert, I’ve learned how cavalier some prescribers are in regard to warning patients about the adverse effects of any psychiatric drugs.

Read entire article:  http://www.huffingtonpost.com/dr-peter-breggin/antidepressants-pilots-ta_b_542240.html

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Congressional Hearings Held On Antidepressant-Induced Suicide In The Military

Wednesday, March 3rd, 2010

The Huffington Post
By Peter Breggin
March 3, 2010

On February 24, 2010 the Veterans’ Affairs Committee of the U. S. House of Representatives chaired by Bob Filner (D-CA) held hearings on “Exploring the Relationship Between Medication and Veteran Suicide.” Military suicides have risen rapidly in recent years at the same time that the prescription of antidepressants and other psychiatric drugs has escalated. The hearing focused on the dangers of the newer antidepressants like Prozac, Paxil, Zoloft, Celexa, Lexapro, Cymbalta, and Effexor.

Starting in the early 1990s, I was the first psychiatrist to write and speak extensively about the newer antidepressants causing suicide, violence, and mania. It was gratifying when Rep. Filner decided to hold the hearings after reading my new book, Medication Madness: The Role of Psychiatric Drugs in Cases of Violence, Suicide and Crime (2008) and called me as his lead witness. I presented scientific evidence that antidepressants cause suicide, violence and mania. I also emphasized the profound danger of prescribing drugs that cause impulsivity, hostility and suicidality to heavily armed young men and women under stress on active military duty. I recommended that the armed services curtail the use of these drugs and rely instead on psychotherapeutic and educational processes that have already proved effective. I also called for additional research in the military and the VA concerning suicide and violence caused by antidepressants.

There is scant evidence for the effectiveness of antidepressants, and overwhelming evidence for their harmfulness. The military is already moving toward the implementation of better educational programs to help active duty soldiers handle stress. These educational programs, and counseling, need to replace the use of psychiatric drugs.

Read entire article:  http://www.huffingtonpost.com/dr-peter-breggin/congressional-hearings-on_b_480613.html

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Before you take that antidepressant, visit website feauturing 3,500 crimes/suicides related to antidepressant use

Monday, January 4th, 2010

Martha Rosenberg
OpEdNews.com
January 3, 2010

With our national love of drugs, sex, celebrities and violence you’d think SSRIstories.com would be more popular.

The 12-year-old web site lists 3,500 crime related news reports linked to the use of SSRI antidepressants with celebrities like Wynona Ryder, Heath Ledger, Brittany Murphy, Anna Nicole Smith, Heather Locklear, Glen Campbell, Carrie Fisher, Sharon Osbourne, Phil Hartman, Princess Di’s driver, Patrick Swayze’s Sister, O.J. Simpson and the Crown Prince of Nepal generously sprinkled in.

You can search and sort stories by drug–Lexapro, Celexa, Luvox, Prozac, Zoloft and Paxil and the related Effexor and Cymbalta–date, location, type of violence and the articles about school shootings, famous cases and legal cases won on SSRI defenses are color coded.

You don’t even have to read the whole article.

SSRIstories founder and manager Betty Henderson pulls out and boldfaces the story’s drug-related citation like Lynyrd Skynyrd harmonicist Mike Caruso’s remark that, “the doctor put me on Cymbalta. That turned me manic,” and Oklahoma murder suspect Ronson Bush’s remark, “I killed my friend when I took these. I’m not going to take them,” when offered SSRIs at the Grady County Jail.

Read entire article: http://www.opednews.com/articles/Before-You-Take-That-Antid-by-Martha-Rosenberg-100103-313.html

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Psychiatric Drugs, Violence and Suicide

Sunday, July 19th, 2009

police_tape_288x195K.L. Carlson
Former Pharmaceutical Rep.
July 19, 2009

People often go through times of depression due to job loss, relocation, loss of a loved one, divorce, and many other situations that cause us to feel insecure. Our bodies do have natural ways of dealing with these emotions especially if people use healthy means including adequate sleep, exercise, healthy eating and emotional support from friends and family.

SSRI/SNRI (Selective Serotonin Reuptake Inhibitors/Selective Norepinephrine Reuptake Inhibitors) are antidepressant drugs that interfere with the body-mind’s normal functioning. These drugs are literally mind-altering.  They can cause people to terminate loving, supportive relationships with family and friends, the very relationships that are extremely important to helping people recover from depression.  The drugs can cause hallucinations, paranoia, and mania.

There is a direct correlation with the increase of antidepressant drug use and the rise in extreme, senseless violent acts.  There are experts who have been trying to bring this to the attention of physicians, the FDA, and the public for more than a decade.  Depression is not the problem.  The drugs are the problem.

In 2001, GlaxoSmithKline was ordered to pay $6.4 million to the surviving family members after 60 year old Donald Schnell flew into a rage and killed his wife, daughter, and granddaughter only 48 hours after he began to take Paxil.

“I keep asking, when is somebody going to see this?  But we’ve been so brainwashed about drugs.  We think legal means safe,” Ann Blake Tracy, Ph.D. explains.  “Most people don’t know that LSD once was legal and prescribed as a wonder drug.  That PCP was considered to have a large margin of safety in humans. Most people don’t know that ecstasy was prescribed and sold for five years to treat depression.

The adverse effects of psychiatric drugs are regularly misdiagnosed as more signs of depression, anxiety or some other created-by-vote psychiatric disorder. Then patients are prescribed additional psychiatric drugs or the dosage is increased.  That was the case of California teenager Dominique Slater.  Only 14 years old she was on several antidepressants including Celexa and Wellbutrin. When her erratic behavior worsened her doctor prescribed double dose of Effexor.  Fifteen days later she killed herself.  She was barely a teenager yet she was prescribed multiple antidepressant drugs at high doses.  The year was 2003. Britain had already sent letters to all physicians sternly warning against the use of any of these drugs in anyone under the age of 18 years.  It took the FDA another year to issue a warning of increased suicide in youths under 18 years old.  No letters were sent to physicians.  And the drug companies created marketing campaigns specifically to get antidepressants into the offices of all types of physicians, not just psychiatrists.

More than 10 million prescriptions for antidepressants are issued each year for children younger than 18 in the U.S.  Any physician, not just psychiatrists, can write prescriptions for psychiatric drugs.  The age of children being given these powerful mind-altering drugs continues to get younger.  Ohio physicians in the month of July 2004 prescribed psychiatric drugs for 696 babies aged newborn to 3 years old covered by Medicaid.

“It’s shocking,” said Dr. Ellen Bassuk, associate professor of psychiatry at Harvard Medical School.  “These medications are not benign.  They can have dangerous side effects.  Who is being helped by children being drugged, the babies or the caregivers?”

Scientific Evidence of Antidepressants’ Effects on Newborns

“When we put pregnant women on antidepressants, they can’t get off them,” an unconcerned gynecologist told my friend C. when she told him she had spent years trying to get off the antidepressant he had prescribed to her.  Three years before this callous physician’s comments to C., the extreme health risks to the fetus had been reported in medical journals.

A study published in The New England Journal of Medicine in February 2006 reports pregnant women taking antidepressants have babies who are 6 times more likely to have primary pulmonary hypertension (PPH) or a developing lung disorder.  PPH is extremely serious. A baby’s organs such as brain, kidney and liver are stressed due to lack of oxygen.  PPH requires neonatal intensive care. PPH can be fatal and for babies who do survive there is often long-term health problems including breathing difficulties, seizures and developmental disorders.

Women taking SSRI/SNRI drugs during the first trimester of pregnancy are at 60 percent greater risk of their babies having heart defects and 40 percent greater risk of their babies suffering malformation.

“In conclusion, our results suggest that maternal exposure to fluoxetine (Prozac, Luvox, Sarafem and Symbyax) during pregnancy and lactation results in enduring behavioral alterations… throughout life,” a study reports in Pharmacology, spring 2007.  Although the study was done with mice the physiological systems are similar to humans.  There is nothing preventing drugs a pregnant woman takes from going directly into the bloodstream and then all the tissues of the fetus.  And as this study indicates, antidepressants are also transferred to the baby through the mother’s milk.

As of February 2009, the drug companies, using their puppets and financial influence, are lobbying the U.S. Senate to pass a bill called the Mothers Act.  This insane bill has already passed the U.S. House of Representatives.  Supposedly this bill is meant to address postpartum depression.  The truth is that it’s the drug industry influencing legislation in order to have more taxpayers’ money flow into drug companies’ profits.  The 1,200 drug industry lobbyists on Capitol Hill are greasing the skids well so that this dangerous legislation that will harm, not help mothers, babies, and American families will easily pass.  It’s about money, not health.

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