Posts Tagged ‘Columbine’

FDA’s Continual Responsibility for Making Our Children Into a Nation of Drug Addicts

Monday, March 28th, 2011

Salem-News.com
By Marianne Skolek
March 28, 2011

Dexedrine

In 1997, 5 million children were listed as using psychotropic drugs, Ritalin being among the most common.  Ritalin use has increased by 700% since 1990. By the year 2000, it was prescribed for approximately 7 million children.

Attention Deficit Hyperactivity Disorder (ADHD) is diagnosed eight times more often in boys than in girls.

Of these diagnosed children, 90% use a stimulant to help control the disorder. 70% of children with ADHD are prescribed Ritalin. 20% use its counterpart, the generic form known as methylphenidate and an amphetamine known as Dexedrine.

Beginning in the 1960s, it was used to treat children with ADHD, or Attention Deficit Disorder (ADD), known at the time as hyperactivity or minimal brain dysfunction (MBD).

Production and prescription of methylphenidate rose significantly in the 1990s, especially in the United States, as the ADHD diagnosis came to be better understood and more generally accepted within the medical and mental health communities.

The benefits and cost effectiveness of methylphenidate, i.e. Ritalin long term are unknown due to a lack of research.

There is a lack of evidence of the effectiveness in the long term of beneficial effects of methylphenidate (Ritalin) with regard to learning and academic performance.

An analysis of the literature concluded that methylphenidate quickly and effectively reduces the signs and symptoms of ADHD in children under the age of 18 in the short term but found that this conclusion may be biased due to the high number of low quality clinical trials in the literature.

Some adverse effects of stimulant therapy may emerge during long-term therapy, but there is very little research of the long-term effects of stimulants.

The United States produces 90% of the world’s Ritalin. It produces, sells and distributes more methylphenidate than any other country worldwide. In addition to the United States, methylphenidate is frequently used in the United Kingdom and Germany.

It is used in many European countries, but in much smaller percentages than in the United States. Some countries don’t use the drug at all, such as Sweden, which has banned its use.

Intuniv

The FDA approved ”Intuniv” – the first non-stimulant extended release medication for the treatment of ADHD in children.  This means it can be administered in one daily dose and given in the morning or at night as a stand-alone medication or in conjunction with another ADHD drug to boost overall effectiveness. Because Intuniv is not a stimulant, parents can feel better knowing that their child is being treated with a medication that does not have addictive properties and is less likely to be abused since it is not a controlled substance.

In clinical trials, Intuniv has been shown to boost the effectiveness of treatment when combined with a stimulant, resulting in greater attention span and reduced levels of impulsivity and hyperactivity.  One possible drawback, however, is that it has not been tested for extended use, beyond  that of 8 to 10 weeks.  For this reason, physicians who prescribe Intuniv must closely monitor patients to determine whether it continues to be a successful protocol for longer term management of ADHD symptoms.

At the present time, Intuniv’s longer term efficacy is unknown and will be determined by physicians who carefully monitor patients being treated and report associated outcomes.  Shire, Intuniv’s biopharmaceutical developer, continues to focus their research on this drug’s long term use potential for maintenance of children with ADHD who need drug treatment in order to succeed academically — as well as socially.

Dr. Ann Blake Tracy

Dr. Ann Blake Tracy, executive director of the International Coalition for Drug Awareness and author of Prozac: Panacea or Pandora? – Our Serotonin Nightmare is an expert consultant in cases like Columbine in which anti-depressant medications are involved.

Tracy says the Columbine killers’ brains were awash in serotonin, the chemical which causes violence and aggression and triggers a sleep-walking disorder in which a person literally acts out their worst nightmare.

Columbine shooter Eric Harris

Shortly before the Columbine shooting, Eric Harris (one of the shooters) had been rejected by Marine Corps recruiters because he was under a doctor’s care and had been prescribed an anti-depressant medication.  Harris was taking Luvox, an anti-depressant commonly used to treat patients with obsessive-compulsive disorder.

Luvox is in a class of drugs called selective serotonin reuptake inhibitors (SSRI).  Other SSRIs include Prozac, Paxil and Zoloft.  An estimated 10 million Americans take anti-depressant medications.

Harris was taking Luvox

Mark Taylor, the first student shot at Columbine, brought a lawsuit against Solvay, the international pharmaceutical company that produces Luvox.  Taylor’s 2001 lawsuit said Luvox had caused Harris to become manic, psychotic, and homicidal/suicidal and had brought about “emotional blunting,” or a lack of inhibition.

Tayor’s lawsuit also faulted Solvay for failing to warn of the “risks and dangers” associated with the drug. *

Columbine victim Mark Taylor

(*Taylor told American Free Press two years after the Columbine shooting, as a 17-year old recovering victim, he had been taken alone, without counsel, into a room with lawyers representing Solvay and threatened with court costs and counter suits.  The fear of financial ruin led Taylor and others to withdraw the lawsuit.  Solvay Pharmaceuticals was able to silence disclosure of exactly what had happened at Columbine — and why — even after its product had played ab obvious role in slaughtering 13 people).

Solvay Pharmaceuticals

In early 1998, according to Taylor’s lawsuit, Harris had taken Zoloft for two months, but soon became “obsessional.”  Harris became obsessed with homicidal and suicidal thoughts “within weeks” after he began taking Zoloft, according to Dr. Tracy.  Due to his obsession with killing, Harris was switched to Luvox, which was in his system at the time of the shooting, according to his autopsy.  The change from Zoloft to Luvox is like switching from Pepsi to Coke, Dr. Tracy said.

Read entire article here:  http://www.salem-news.com/articles/march282011/child-addicts-ms.php

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Nation of Pill Poppers: 19 Potentially Dangerous Drugs Pushed By Big Pharma

Tuesday, December 7th, 2010
AlterNet — December 6, 2010
by Martha Rosenberg
Here are some of the dicey drugs many Americans are hooked on,
thanks to greedy pharmaceutical companies.

Since direct-to-consumer drug advertising was legalized 13 years ago, Americans have become a nation of pill poppers — choosing the type of drug they desire like a new toothpaste, sometimes whether or not they need it.

But if patients want the drugs, doctors and pharma executives want them to have the drugs and media gets full page ads and huge TV flights (when many advertisers have dried up), is the national pillathon really a problem?

Yes, when you consider the cost of private and government insurance and the health of patients who take potentially dangerous drugs like these.

Seroquel, Zyprexa, Geodon, atypical antipsychotics

Even though the antipsychotic Seroquel surpasses 71 drugs on the FDA’s January quarterly report with 1766 adverse events, even though it’s linked to eight corruption scandals, even though military parents blame Seroquel for unexplained troop deaths, it is the fifth biggest-selling drug in the world and netted AstraZeneca almost $5 billion last year.

Atypicals were originally promoted to replace side-effect prone drugs like Thorazine but soon became pharmaceutical Swiss Army Knives for depression, anxiety, insomnia, bipolar and conduct disorders and other off label uses — and betrayed the same side effects as older antipsychotics. (Especially tardive dyskinesia-linked Abilify.)

Foisted disproportionately on the young, poor and disadvantaged, atypicals cause such weight gain and metabolic derangement — 16 percent of Zyprexa patients gain 66 pounds and some gain over 100 — manufacturer Lilly Eli Lilly agreed to pay the state of Alaska $15 million in 2008 for the Medicaid costs of Zyprexa patients who developed diabetes.

Atypicals carry warnings of death in demented patients but are widely used in nursing homes. And even though Risperdal maker Johnson & Johnson, Geodon maker Pfizer, Abilify maker Bristol-Myers Squibb, Lilly and AstraZeneca have all entered into government settlements that acknowledge fraudulent or wrongful atypical marketing, FDA rewarded atypical makers by approving Zyprexa and Seroquel for children last year. And approved a new atypical antipsychotic, Latuda, in October. Maybe the FDA is bipolar.

Ritalin, Concerta, Strattera, Adderall and ADHD drugs

When it comes to the epidemic of 5.3 million US children between 3 and 17 diagnosed with ADHD, suspicions of pharma pushing the disorder are exceeded only by pharma’s admissions thereof.

During an August conference call with financial analysts, Shire specialty pharmaceuticals president Mike Cola credited the “very dynamic ADHD market” to Shire’s globalization efforts and “investments we have made in new uses for our existing products.”

Those uses, a.k.a. diagnoses, for Shire products like stimulants Adderall, Vyvanse and Intuniv include adult ADHD, cognitive impairment, depression and excessive daytime sleepiness.

Still, Cola says despite the 10 percent ADHD “new starts” that are helping Shire “grow the market,” and the “co-administration market” of add-on prescription drug$, the ADHD franchise suffers from patients who drop out when they quit seeing their pediatrician. “We don’t see those patients show up again until their mid-to-late 20s,” laments Cola.

ADHD drugs, in addition to “robbing kids of their right to be kids, their right to grow, their right to experience their full range of emotions, and their right to experience the world in its full hue of colors,” as Anatomy of an Epidemic author Robert Whitaker puts it, can also be deadly.

A 2009 article in the American Journal of Psychiatry called Sudden Death and Use of Stimulant Medications in Youths found 1.8 percent of youthful stimulant users died sudden deaths from cardiac dysrhythmia or unexplained causes versus 0.4 percent who were not on stimulants. Though it helped fund the study, the FDA said the results proved no “real risk” and kids should keep taking their meds.

Meanwhile, says Robert Whitaker, kids on ADHD meds “are told they are going to be on these drugs for life. And next thing they know, they’re on two or three or four drugs,” a phenomenon also known as the co-administration market.

Prozac, Paxil, Zoloft, SSRIs

Selective serotonin reuptake inhibitor (SSRIs) antidepressants like Prozac, Paxil, Zoloft and Lexapro probably did more to inflate pharma profits in the last decade than direct-to-consumer advertising and Viagra put together, no pun intended: over 60 million prescriptions were filled in the US in 2007 with many patients reporting their depression lifted.

But some critics say for mild depression, SSRIs don’t work at all and are no better than placebo.

And others say they can add aggression, bizarre behavior, self-harm and suicidal thoughts to depression. In fact, there are 4,200 published reports of SSRI-related violence, aggression, bizarre behavior, self-harm and suicide since the drugs were introduced in 1988 including the well known gun massacres at Columbine (1999), Red Lake (2005), NIU and likely, Virginia Tech (2007).

SSRIs have non-behavioral perks both sides agree on: life-threatening serotonin syndrome when taken with migraine drugs, gastrointestinal bleeding when taken with aspirin, Aleve or Advil and the bone condition, osteoporosis.

Paxil can reduce or abolish the effect of tamoxifen in breast cancer patients and increase deaths says British Medical Journal. It’s linked to a two-fold increased risk of cardiac birth defects in infants according to its own manufacturer, GSK.

And sex? SSRIs are so linked to dysfunction even the pharma-identified web site WebMD admits many will experience impotence, delayed ejaculation or no orgasm. But there is a solution (besides going off SSRIs) says WebMD: Add another antidepressant that’s not an SSRI, like Wellbutrin!

Effexor, Cymbalta, Pristiq, SNRIs

Selective norepinephrine reuptake inhibitors (SNRIs) are like their SSRIs chemical cousins except their norepinephrine effects can modulate pain, which has ushered in your-depression-is-really-pain, your-pain-is-really-depression and other crossover marketing. But the problem with giving a psychoactive drug for pain is that you’re giving a psychoactive drug for pain. “After three months of taking Savella [another SNRI], I started self-destructing and cutting myself,” writes a 40 year old woman on askapatient.com. “I don’t know why or anything, but it does similar to Prozac where it makes you think and do weird things.”

And Cymbalta, approved this fall for chronic back pain and osteoarthritis?

Cymbalta was the drug healthy 19-year-old volunteer Traci Johnson was testing when she hung herself in an Eli Lilly dorm in 2005. It was the drug Carol Anne Gotbaum killed herself on at Phoenix’s Sky Harbor airport in 2007.

SNRI’s are also harder to quit than SSRIs, especially Effexor. 25-year-old Chicagoan David F. told AlterNet he stood at the top of an 8-story parking lot contemplating jumping every day for weeks after quitting. It’s also the drug Andrea Yates was on when she drowned her five children in 2001.

But not all SNRI side effects are behavioral. The FDA would not approve Pristiq, a newer version of Effexor, when Wyeth/Pfizer tried to market it for vasomotor symptoms, because it caused heart attacks, coronary artery obstruction and hypertension in clinical trials. That’s similar to another SNRI, the diet pill Meridia, which was just withdrawn from the market for causing heart problems. Pristiq is still available.

Read the rest of the article here: http://www.alternet.org/story/149078/nation_of_pill_poppers_19_dangerous_drugs_shamelessly_pushed_by_big_pharma?page=entire

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US Soldiers’ Suicides Caused by Prescription Drugs?

Monday, November 1st, 2010

The Epoch Times, November 1, 2010

by Martha Rosenberg

The suicide rate among U.S. troops is astonishing.

In 2009 there were 239 suicides within the Army, including the Reserves, 160 active duty suicides, 146 active duty deaths from drug overdoses and high-risk behavior, and 1,713 suicide attempts, says the Army’s suicide report released in July.

More troops are dying from their own hands than in combat, says the Army report, titled “Health Promotion, Risk Reduction, and Suicide Prevention.” Thirty-six percent of the suicides were among troops who were never deployed.

Also astonishing is the psychoactive prescription drug rate among active duty-aged troops, aged 18 to 34, which is up 85 percent since 2003, according to the military health plan, Tricare. Including family prescriptions, since 2001, 73,103 prescriptions for Zoloft have been dispensed, 38,199 for Prozac, 17,830 for Paxil, and 12,047 for Cymbalta. All of the drugs carry a suicide-warning label.

In addition to the spike in SSRI antidepressant prescriptions, prescriptions for the anticonvulsants Topamax and Neurontin rose 56 percent in the same group since 2005, says Navy Times. The FDA warned last year that taking these drugs doubles suicidal thinking.

In fact, 4,994 troops at Fort Bragg, N.C., are on antidepressants right now, says the Fayetteville Observer. Six hundred and sixty-four are on an antipsychotic and “many soldiers take more than one type of medication.”

Troops may also be taking Chantix, an antismoking drug so linked to violence and self-harm that Secretary of Veterans Affairs James Peake was forced to defend its use before the House Committee on Veterans Affairs in 2008 even in drug trials. Related Articles

“If you know the drug induces suicidal thoughts,” an unappeased committee chair Bob Filner, D-Calif., asked Rep. Filner, “Why don’t you just stop [prescribing it]?”

The FDA says that even widely prescribed asthma drugs like Singulair and Advair are linked to suicide and have been cited in young people’s deaths.

Who knows what happens when the drugs are mixed with mood stabilizers, insomnia meds, pain pills, anti-anxiety drugs, and antipsychotic pills? These drug combinations have never been tested for safety.

Links between suicide and even murder-suicide and selective serotonin reuptake inhibitors (SSRI) and serotonin-norepinephrine reuptake inhibitors (SNRI) antidepressants have been long recognized.

Traci Johnson, a healthy 19-year-old with no mental problems, hung herself during Lilly trials of Cymbalta in the drugmaker’s own clinic in 2004. Columbine shooter Eric Harris had reportedly just switched from Zoloft to Luvox.

Red Lake shooter Jeff Weise who killed 10 on a Minnesota Native American reservation in 2005 had just upped his Prozac dose. And the Virginia Tech shooter, Cho Seung-Hui, was also on psychoactive medications, say news reports.

Even though Americans have doubled their antidepressants since 1999 so that 10 percent of the population or 27 million now take them, suicides have climbed by 5 percent since 1999 and 16 percent in middle-aged adults, says an article in the American Journal of Preventive Medicine in 2008.

In fact, the high percentage of civilian suicides on psychoactive drugs is probably the clearest indication that military life is not the only cause of the shocking troop suicides.

In September alone, there were 18 civilian suicides, 11 murders, 2 murder-suicides, and other violence linked to people who were using or had used antidepressants, according to published reports. (Ssristories.com/index.php?sort=what&p=recent)

A 54-year-old patient with a breathing tube and an oxygen tank and no previous criminal record held up a bank in Mobile, Ala. She had gone off her antidepressants.

An enraged man in Australia, also off his antidepressants, chased his mailman and threatened to cut his throat for bringing him junk mail.

A 58-year-old Amarillo, Texas, man with no criminal history tried to abduct three people, killing an Oklahoma grandmother in the process. He had “an antidepressant in his blood,” said police.

Also in the 30-day period, a 60-year-old grandmother in Seattle killed three family members and herself; a disc jockey in Bristol, U.K., set himself on fire; and a man in Exeter, U.K., was found to have stabbed himself in the heart. All were on antidepressants.

Finally, in the month of September, legal proceedings began against two mothers and a father charged with killing their own children.

Over 4,000 published reports of violent and bizarre behavior of people affected by antidepressants on the Web archive ssristories.com reveal the same out-of-character violence and self-harm in civilians that is currently seen in the military.

Twenty people set themselves on fire. Ten bit their victims (including a biter who was sleepwalking and a woman, on Prozac, who bit her 87-year-old mother into a critical condition.) Three men in the 70s and 80s attacked their wives with hammers.

Many stabbed their victims obsessively—one even stabbed furniture after killing his wife—and 14 parents drowned their children, a crime seldom heard of before the 2001 Andrea Yates case. Yates, who drowned her five children, was on the antidepressant Effexor, which manufacturer Wyeth (now Pfizer) “issued no public warning” about [the possibility of violent behavior], says the Associated Press.

Then there was the North Carolina pilot on Zoloft who sang “I’m going down for the last time” into the cockpit voice recorder before he crashed his plane in June. And the mayor of Coppell, Texas, Jayne Peters, who killed herself and her daughter in July over the grief of losing her husband. Police found antidepressants at the home.

Such murder-suicides committed by women used to be rare, says Betty Henderson the ssristories.com moderator and researcher. “Before the SSRI antidepressants, women committed 5 percent of the murder-suicides, and now they account for almost 15 percent of this type of violence,” she said in an interview.

Antidepressants are also causing women to become sexual predators, says Henderson. “There have been more than a dozen recent cases of women school teachers molesting their young students under the influence or withdrawal of antidepressants. Who heard of this type of sexual aberration before the antidepressant craze?”

Why don’t doctors and media outlets publicize the names of these volatile drugs?

“It’s a good question,” said Dr. Gary Kohls, a Minnesota family practitioner, in an op-ed written after Iraq veteran Matthew Magdzas killed his pregnant wife, their 13-month-old daughter, their dogs, and himself in Wisconsin in August.

“Nobody in the media has, to my knowledge, had the courage to report what the drugs were, nor have they interviewed the physician or his clinic to find out the rationale for prescribing drugs that have common violence-inducing effects (with black box warnings stating that in the prescribing information),” he writes. “Therefore nothing has been learned from this important teachable moment, probably because revealing the common reality of prescription drug-induced violence would be economically harmful for the sacred cows of Big Pharma and Big Medicine.”

Sen. Jim Webb, D-Va., called the fact that one of every six troops are now on psychoactive drugs “pretty astounding and also very troubling,” in Senate hearings this year.

Retired Col. Bart Billings, a former Army psychologist who has also testified before Congress, says, “I feel flat-out that psychiatrists are directly responsible for deaths in our military, for some of these suicides,” in a March Marine Times article. “I think it’s criminal, what they are doing.”

Even Katie Bagosy, the wife of Marine Sgt. Tom Bagosy, who took his own life in May, indicts the Neurontin medication he was prescribed for his downfall.

“He told me, ‘It all started to get worse when I got on this medication.’ Looking back, that was the beginning of the end,” she says in an article called “A Prescription for Tragedy” in the current National Journal.

http://www.theepochtimes.com/n2/content/view/45181/

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The real lowdown on Antidepressants: All Doped Up

Wednesday, August 5th, 2009

R. Cort Kirkwood
The New American
August 5, 2009

Between 1996 and 2005, Reuters reports, the use of anti-depressants doubled to nearly 10 percent of the American population. In 1996, the figure was 13 million. Now, it’s 27 million.

Those numbers, obviously, should cause some worry.

For one thing, the suicide rate for middle-aged people is rising, Reuters reported, suicide being a risk factor in taking antidepressants. According to the Journal of Preventative Medicine, the suicide rate for middle-aged Americans increased 16 percent from 1999 to 2008, which roughly coincides with the massive increase in anti-depressant use.

Indeed, such is the risk for suicide that each container carries a “black box warning.” The Food and Drug Administration issued the mandate to carry the warning in 2007. Studies had shown the drugs increased the risk of suicide in teens and children. Clearly, as the psychiatrist quoted for the Reuters piece suggested, they might just increase the risk for the middle-aged as well.

For another thing, while these folks, most of them baby boomers, are usually killing only themselves, their children aren’t. The baby boomers’ kids take others with them before they commit suicide.

Recall that several of the notorious school shooters were taking such medications, most notably Eric Harris, one of the two shooters at Columbine High in Colorado. Harris and his partner, Dylan Klebold, slaughtered 12 students and a teacher, while injuring 21, before killing themselves. Harris was taking Luvox.

Read entire article:  http://www.thenewamerican.com/index.php/usnews/health-care/1595

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