Posts Tagged ‘anti-psychotic’

Drugged to Death: Soldiers returning from war are being given deadly cocktails of psychiatric drugs

Tuesday, March 9th, 2010

AlterNet
By Martha Rosenberg
March 9, 2010

Sgt. Eric Layne’s death was not pretty.

A few months after starting a drug regimen combining the antidepressant Paxil, the mood stabilizer Klonopin and a controversial anti-psychotic drug manufactured by pharmaceutical giant AstraZeneca, Seroquel, the Iraq war veteran was “suffering from incontinence, severe depression [and] continuous headaches,” according to his widow, Janette Layne.

Soon he had tremors. ” … [H]is breathing was labored [and] he had developed sleep apnea,” Layne said.

Janette Layne, who served in the National Guard during Operation Iraqi Freedom along with her husband, told the story of his decline last year, at official FDA hearings on new approvals for Seroquel. On the last day of his life, she testified, Eric stayed in the bathroom nearly all night battling acute urinary retention (an inability to urinate). He died while his family slept.

Sgt. Layne had just returned from a seven-week inpatient program at the VA Medical Center in Cincinnati where he was being treated for post-traumatic stress disorder (PTSD). A video shot during that time, played by his wife at the FDA hearings, shows a dangerously sedated figure barely able to talk.

Sgt. Layne was not the first veteran to die after being prescribed medical cocktails including Seroquel for PTSD.

Read entire article:  http://www.alternet.org/world/145892/are_veterans_being_given_deadly_cocktails_to_treat_ptsd

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Drugging Kids For Profit: Powerful & dangerous antipsychotic drugs being used on kids more and more often

Monday, January 4th, 2010

Ed Silverman
Portfolio.com
January 4, 2010

If elderly people with dementia are so vulnerable to the risks posed by antipsychotics, why are so many nursing-home residents regularly prescribed the medications?

The answer can be found in a controversy with its roots in aggressive marketing and lackadaisical supervision. Known in the medical community as atypical antipsychotics, this group of drugs was originally approved by the Food and Drug Administration to treat adults suffering from schizophrenia. They go by snazzy names such as Zyprexa, Geodon, Abilify, and Seroquel. Later, regulators allowed doctors to prescribe them for treating bipolar disorder. Over the past decade, the pills have become a veritable goldmine; in 2008 alone, sales in the U.S. reached $14.6 billion.

But critics say those big sales are actually due, in part, to an epidemic of off-label marketing, which is promoting a drug for unapproved uses, although doctors are free to write a prescription regardless. And so drugmakers encouraged doctors to prescribe these meds for children before the FDA sanctioned their use for youngsters. This was particularly troubling, given that the drugs can cause diabetes and weight gain, side effects that prompted thousands of lawsuits claiming that drugmakers tried to hide evidence of these problems.

Read entire article: http://www.portfolio.com/industry-news/health-care/2010/01/04/drugging-kids-for-profit/

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Big Pharma paid $500,000 to Chicago psychiatrist who used children as guinea pigs

Sunday, December 20th, 2009

E. Huff
NaturalNews.com
December 18, 2009

A federal lawsuit has been filed against pharmaceutical giant AstraZeneca for its role in paying Chicago psychiatrist Dr. Michael Reinstein nearly $500,000 over the course of a decade to conduct research and to promote its anti-psychotic drug, Seroquel. Reinstein is being accused of wrongfully preying on thousands of mentally-ill patients in order to rake in profits for AstraZeneca.

Reinstein has a long history of working with AstraZeneca, receiving regular payments for speeches he would make across the country promoting the drug. AstraZeneca was also paying a for-profit research company, Uptown Research Institute, who in turn was paying Reinstein consulting fees for his services.

Cited in the lawsuit was the fact that Reinstein would continually prescribe roughly double the amount of drugs other psychiatrists would prescribe for the same conditions. When patients would report their pain and suffering due to the tremendous side effects of such drugs and their abnormally high dosages, Reinstein would largely ignore their concerns.

Read entire article: http://www.naturalnews.com/027765_psychiatrists_Seroquel.html

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Tighter rules sought against using anti-psychotic drugs to chemically restrain the frail & elderly

Sunday, December 20th, 2009

Sam Roe and Christina Jewett
Chicago Tribune
December 20, 2009

Health advocates are calling for tough new rules on the use of anti-psychotic drugs in Illinois nursing homes, including tighter controls on doctors who prescribe the powerful medications.

“Medical care should help you get better, not get worse,” said Wendy Meltzer of Illinois Citizens for Better Care, an advocacy group for nursing home residents.

A Tribune investigation recently showed how many frail and vulnerable Illinois nursing home residents have been unnecessarily dosed with anti-psychotics, leading to harm and an increased risk of death. One psychiatrist, the Tribune found in a joint investigation with ProPublica, provided assembly-line care to thousands of mentally ill patients.

The advocates want Gov. Pat Quinn’s Nursing Home Safety Task Force to address these problems. While the task force has focused on violent felons housed in nursing facilities, chairman Michael Gelder said the group will also target the misuse of psychotropic drugs.

Read entire article: http://www.chicagotribune.com/health/chi-psychotropics-reformdec20,0,3977364.story

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Drugmaker pays psychiatrist nearly $500,000 to promote antipsychotic drug Seroquel despite misgivings about his research

Friday, November 13th, 2009

Christina Jewett, ProPublica
SamRoe, Chicago Tribune
November 11, 2009

Executives inside pharmaceutical giant AstraZeneca faced a high-stakes dilemma.

On one hand, Chicago psychiatrist Dr. Michael Reinstein was bringing the company a small fortune in sales and was conducting research that made one of its most promising drugs look spectacular.

On the other, some worried that his research findings might be too good to be true.

As Reinstein grew irritated with what he perceived as the company’s slights, a top executive outlined the scenario in an e-mail to colleagues.

“If he is in fact worth half a billion dollars to (AstraZeneca),” the company’s U.S. sales chief wrote in 2001, “we need to put him in a different category.” To avoid scaring Reinstein away, he said, the firm should answer “his every query and satisfy any of his quirky behaviors.”

Putting aside its concerns, AstraZeneca would continue its relationship with Reinstein, paying him $490,000 over a decade to travel the nation promoting its best-selling antipsychotic drug, Seroquel. In return, Reinstein provided the company a vast customer base: thousands of mentally ill residents in Chicago-area nursing homes.

Read entire article: http://www.chicagotribune.com/health/chi-drugs-seroquel-reinsteinnov11,0,6067737.story

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Children on antipsychotics 3 times more likely to develop diabetes (a known side effect of antipsychotics)

Thursday, November 12th, 2009

Kelly Sinoski
Vancouver Sun
November 11, 2009

Children and youth on certain antipsychotic medications are more prone to getting diabetes and becoming fat, according to a new study published in the Canadian Journal of Psychiatry.

But the British Columbia doctors involved in the two-year study say parents shouldn’t rush to take their children off the drugs and instead should consult their physicians on ways to monitor and beat the metabolic side-effects.

“On the one hand, the medication has significant and worrying side-effects,” said study co-author Dr. Jana Davidson, medical director of child and adolescent mental health and addiction programs at BC Children’s Hospital.

“On the other hand, in some of these cases the kids being on medication is what allows them to function in their lives and allows them to stay in their families.”

About 6,000 youth in B.C. are on antipsychotic medications and prescription rates have been soaring in the past five years, according to the study.

Between 2002 and 2006, prescriptions of atypical or second-generation antipsychotics for B.C. youth rose by about 22 per cent, from one in 200 youth to one in 154.

Read entire article: http://www.vancouversun.com/health/Children+antipsychotic+drugs+more+prone+diabetes+Canadian+study/2212393/story.html

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Eli Lilly to pay $24 million in Utah Attorney General’s Zyprexa lawsuit/AG says “we want their bad conduct to stop”

Thursday, November 12th, 2009

Geoff Leisik
Deseret News
November 11, 2009

Pharmaceutical giant Eli Lilly and Co. has agreed to pay $24 million to settle a lawsuit filed by the Utah Attorney General’s Office.

Attorney General Mark Shurtleff sued the company after a nearly four-year investigation revealed that Lilly concealed its knowledge of significant weight gain and obesity associated with the anti-psychotic medication Zyprexa. Investigators also showed that Lilly’s sales representatives illegally promoted the drug for uses not approved by the U.S. Food and Drug Administration.

“We’re not just asking them for money. We want their bad conduct to stop,” Shurtleff said Wednesday while announcing the settlement.

“As part of the settlement agreement, there are corporate integrity responsibilities and remedial provisions that will continue to be monitored by the court to stop (Lilly’s) harmful behavior.”

Zyprexa is approved for the treatment of schizophrenia and certain types of bipolar disorder in adults. But authorities say that in 1999, Lilly’s marketing arm that focuses on doctors who treat the elderly began encouraging physicians to prescribe the drug for dementia, Alzheimer’s disease, agitation, aggression, hostility, depression and generalized sleep disorder without prior FDA approval. Lilly also trained its sales teams to avoid discussions with health-care professionals about the weight gain side effect, investigators said.

Read entire article: http://www.deseretnews.com/article/705343716/Firm-to-pay-Utah-24M-in-settlement.html

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Report finds nearly 2,000 elderly patients killed each year by anti-psychotic drugs

Thursday, November 12th, 2009

Owen Bowcott
Guardian.co.uk
November 12, 2009

As many as many as 144,000 people suffering from dementia are being given anti-psychotic drugs unnecessarily, according to a review ordered by the Department of Health.

Excessive use of the medication causes an estimated 1,800 deaths and almost as many strokes among older people every year, the study revealed.

The care services minister, Phil Hope, accepted all the recommendations in the review and promised a fundamental change in the treatment of those suffering from dementia.

The numbers being given “chemical restraints” will be reduced, extra training will be given to nursing home staff, more psychological therapies are to be made available and a national clinical director for dementia will be appointed.

The author of the study, Sube Banerjee, professor of mental health and ageing at the institute of psychiatry at King’s College London, said that as few as 36,000 patients were benefiting from the use of anti-psychotic drugs, but their use was widespread and usually unquestioned.

Read entire article: http://www.guardian.co.uk/society/2009/nov/12/anti-psychotic-drugs-kill-dementia-patients

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