Archive for January, 2010

New allegations of suppressed drug data surface as thousands sue over antipsychotic drug causing weight gain/diabetes

Friday, January 29th, 2010

BBC News
January 26, 2010

The marketing team sued over a drug’s alleged side effects tried to suppress key data, an ex-employee has claimed.

Seroquel’s former UK medical adviser told the BBC he was pressured to approve promotional material which said weight gain was not an issue.

Maker AstraZeneca, which faces fresh legal action next month, said it took concerns about its conduct seriously.

In the same programme, the British Medical Journal editor urged that the medicine licensing system be reviewed.

Dr Fiona Godlee said industry should no longer provide the evaluations of its own drugs which the licensing body considered.

‘Job threat’

Thousands of patients are suing AstraZeneca in US courts, claiming the anti-psychotic drug Seroquel caused weight gain and diabetes.

The patients allege Seroquel, its second biggest selling drug worth $4.5bn (£2.7bn) a year, was marketed without adequate warning about possible side effects such as massive weight gain and the development of diabetes. However, this is denied by the company.

Read entire article:  http://news.bbc.co.uk/2/hi/health/8478924.stm

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Harvard psychologist links America’s growing number of obese children & adults to psychiatric drug use

Friday, January 29th, 2010

InjuryBoard.com
By David Mittleman
January 29, 2010

Obesity is an epidemic–or at least a major concern for many Americans. We obsess over diet fads, exercise machines, portion control, and The Biggest Loser, all in an effort to get our ballooning waistlines in check. However, according to some researchers, we are looking in all the wrong places for the reason why we’re so fat. Instead of oversized and calorie-laden fast food meals, at least one expert is starting to wonder if the cause of our nation’s weight gain is prescription psychiatric drugs.

Paula J. Caplan, a clinician and research psychologist at Harvard University, suspects that the seemingly non-serious “side effects” of psychiatric medications are to blame for our weight problems. She argues that the sudden weight gain of many Americans occurred during the same time period that psychiatric drugs picked up in popularity–that is, the average weight of an adult has increased by 25 pounds since 1960 while prescriptions of psychiatric drugs to US adults also increased by 73% between 1996 and 2006 alone. What troubles Caplan even more so is that children aren’t left out of the equation. In fact, over the past two decades the number of obese children has tripled while prescriptions of psychiatric drugs to children from 1996-2006 increased by 50%.

Read entire article:  http://lansing.injuryboard.com/fda-and-prescription-drugs/are-psychiatric-medications-causing-your-weight-gain.aspx?googleid=277442

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In addition to causing birth defects & preterm labor—new study says antidepressants cause breastfeeding problems

Thursday, January 28th, 2010

AttorneyAtLaw.com
January 27, 2010

Taking Prozac, Paxil, or other antidepressants from the class of drugs called selective serotonin reuptake inhibitors (SSRIs) can cause delays in lactation in new mothers and difficulty in breast-feeding newborns, a new study says.

Researchers from the University of Cincinnati found SSRIs can result in delayed secretory activation after giving birth. SSRIs regulate the hormone serotonin in the body to stave off depression, but the hormone also is crucial to the breasts’ ability to deliver milk when it is needed, the study’s authors said.

A delay in breast milk production caused by taking SSRIs can “impact serotonin regulation in the breast, placing new mothers at greater risk of a delay in the establishment of a full milk supply,” the study found.

The study’s findings are troubling because millions of people take Prozac, Paxil, and other brands of SSRIs to treat a variety of depression-related disorders. Paxil and other SSRI drugs have been linked before to other serious health complications, including heart-related birth defects and pre-term labor.

Read entire article:  http://www.attorneyatlaw.com/2010/01/prozac-and-paxil-can-cause-breast-feeding-problems-new-study-says/

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Investigating ADHD: No evidence of brain malfunction, biological or genetic abnormality has ever been discovered

Wednesday, January 27th, 2010

The Bitter Pill
By Ashleigh Stewart
January 26, 2010

As scientific as the name may sound ‘Attention Deficit Disorder’ and ‘Attention Deficit Hyperactivity Disorder’ (AD/HD) are alleged and somewhat mysterious ‘diseases’ of which, despite numerous studies dedicated to investigating their cause, no convincing evidence of any brain malfunction or other biological or genetic abnormality has been discovered.

Despite the fact that the source of this ‘so-called’ disease is still vague, the symptoms that define AD/HD are prevalent and prominent, so much so that approximately 6 million children in America alone have been diagnosed with an attention deficit disorder and prescribed with psycho-stimulant drugs, such as ‘Methylphenidate’, otherwise known by it’s brand name ‘Ritalin’, as the primary method of treatment.

My question is what is AD/HD? Why are so many children being diagnosed with it these days, and what could be the real cause of it? Also, how much do we really know about the effects of stimulant drugs on our children? How will taking these drugs affect children’s lives physiologically, psychologically, emotionally and socially as they grow up? Also, what are the implications in terms of the future of the human race and our world if we keep drugging millions of our children with dangerous and highly addictive drugs?

Read entire article:  http://uniteforlife.wordpress.com/2010/01/26/weird-science-investigating-attention-deficit-disorder/

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Kickbackers’ motto: ‘Do no harm’ (to profits)—How drug company used kickbacks to get patients on psych drugs

Tuesday, January 26th, 2010

Boston Globe
By Donald A. MacGillis
January 26, 2010

TALK ABOUT death panels. The US attorney in Boston recently filed suit against the world’s largest maker of health products, Johnson & Johnson, for using kickbacks to get more nursing home patients onto its drugs, including one that was later found to be so lethal to the elderly it had to carry a black-box warning. The government’s complaint leaves little doubt that the drug company acted in a predatory way to increase sales and market share for its products, especially Risperdal, an antipsychotic often used to keep Alzheimer’s and dementia patients under control.

Risperdal is used principally for the treatment of schizophrenia and bipolar disorder. Doping the elderly into placidity is an off-label use of the drug, one that the Food and Drug Administration finally cautioned against in 2005. The reason for the black box warning the FDA required? Too many of the elderly who got the drug were dying.

There is one other reason to thank the federal government for going after the suspect payments Johnson & Johnson made to the middleman to juice up sales of its drugs: Since Medicaid covers most of the nursing home patients, the taxpayer ends up paying much of the bill.

The middleman between Johnson & Johnson and the nursing homes is Omnicare, the country’s largest pharmacy for nursing homes. Last November, it agreed, without “any finding of wrongdoing’’ or “any admission of liability,’’ to a $98 million settlement with the government for its role in helping Johnson & Johnson boost sales to nursing homes. The government says that between 1999 and 2004 Omnicare received tens of millions of dollars in the form of escalating rebates based on greater market share for Johnson & Johnson drugs and in payments ostensibly made by Johnson & Johnson for “data’’ from Omnicare, much of which Omnicare never provided. Other kickbacks, the government says, came in the form of “grants’’ and “educational funding.’’

Read entire article:  http://www.boston.com/bostonglobe/editorial_opinion/oped/articles/2010/01/26/kickbackers_motto_do_no_harm_to_profits/

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America’s exportation of mental disorders and drugs “Making the rest of the world crazy”

Monday, January 25th, 2010

Boston Globe
By Ethan Gilsdorf
January 24, 2010

Americans are a generous people. We donate riches to needy countries. We send our troops abroad. We have exported some of history’s most influential cultural, scientific, and social inventions: democracy, fast food, and Britney Spears.

Whether that generosity is helpful to other nations is another question. And so it goes with mental health. According to Ethan Watters in “Crazy Like Us: The Globalization of the American Psyche,’’ the American way of perceiving and treating mental illness has quickly and ruthlessly become the worldwide way.

What is lost are local customs, beliefs, and practices that worked fine before the invention of antidepressants and antipsychotics. For example, people who suffer from schizophrenia in some developing nations tend to cope better than those in industrialized nations armed with “Diagnostic and Statistical Manual of Mental Disorders’’ diagnoses. Why? In East Africa, for example, traditional beliefs in spirit possession help families accept schizophrenia and reduce social stigma. But Western ideas have “the effect of stripping away the local beliefs’’ that in practice can make people feel better.

Watters, who wrote “Urban Tribes,’’ an examination of the “never-married’’ generation, and “Making Monsters,’’ an indictment of the false memory movement, blends scholarship, journalism, and travel reportage to unearth this hidden story of good intentions in the mental health profession gone awry.

“Crazy Like Us’’ is both groundbreaking and shocking. By focusing on four countries and four disorders – anorexia in Hong Kong; post traumatic stress disorder in post-tsunami Sri Lanka; schizophrenia in Zanzibar, Tanzania; and depression in Japan – Watters shows how American mental health professionals and pharmaceutical companies, sometimes accidentally, sometimes insidiously, have actually hastened the spread of some Western disorders.

Read entire article:  http://www.boston.com/ae/books/articles/2010/01/24/making_the_rest_of_the_world_crazy/

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Think They Don’t Electroshock People Anymore? Think Again–Even toddlers and pregnant women are being shocked

Sunday, January 24th, 2010

By Dr. John Breeding, author of The Wildest Colts Make the Best Horses

child close-upAsk the average person about the use of electroshock treatment in today’s society and 9 out of 10 will respond, “They still shock people?”

They do. It’s estimated that more than 100,000 Americans are electroshocked each year; half are 60 and older, and two-thirds are women. In Australia, it was recently revealed that psychiatrists had electroshocked 55 toddlers age four and younger. In the UK, three year olds have been brutalized with it. And one of the country’s leading mental health “patients’ rights” groups—the National Alliance of Mental Illness (NAMI)—recently endorsed the use of electroshock on pregnant women. One would wonder why a patients’ rights group would endorse such an obviously harmful procedure if not for the fact that the group has recently been exposed as a major front for the psycho/pharmaceutical industry.

The FDA reports pregnant women miscarrying following ECT, while studies show that in addition to the risk of death, the fetus can suffer malnutrition, dehydration and violent injury. Electroshocking children, pregnant women and the unborn is tantamount to torture and should not only be banned but those administering it prosecuted.

Given the factual truths of sending up to 360 volts of electricity searing through the brain – the obvious question is why the “treatment” has not gone by the wayside like its psychiatric sister treatments during the 1940s and 1950s, insulin coma shock and lobotomy.

Electroshock was indeed challenged, and its low point pretty much coincided with the release in 1975 of the Academy Award-winning film version of Ken Kesey’s One Flew Over the Cuckoo’s Nest and Jack Nicholson’s portrayal of the feisty Randle Patrick McMurphy. The horrible scene of his undergoing “unmodified” shock treatment, i.e., without anesthetic and muscle-paralyzing drugs, along with his reduction to a vegetative state was seared in the public’s mind. This, together with public exposure of the shameful state of psychiatric institutions, certainly gave electroshock treatment a bad name—so much so that the treatment was renamed Electroconvulsive Therapy (ECT). The bad publicity caused its use in public institutions to fall sharply, and its overall use was also considerably diminished. It would be naïve, however, to think that this curtailment was strictly due to increased public awareness about the brutalities of the procedure. The advent of neuroleptics (nerve-seizing drugs) was perhaps the major factor in this development. The indiscriminate use of these drugs replaced the indiscriminate use of ECT as the primary means of subduing and pacifying inmates who resisted incarceration and wouldn’t cooperate.

In the last two decades, however, electroshock has made a comeback.

Most electroshock is insurance-covered. ECT specialists on average have incomes twice that of other psychiatrists. The cost for inpatient ECT ranges from $50,000 to $75,000 per series (usually 8 to 12 individual sessions). Electroshock is a multibillion-dollar-a-year industry—yet its damaging effects are well known to those who endorse it.

Max Fink, a professor of psychiatry and the “Grandfather of American ECT” believed the “therapeutic” effect from ECT is produced by brain dysfunction and damage. “Effects on memory, common in ECT, come in two flavors,” wrote Fink in Psychiatric Times in 2006. “Delirium is common with each seizure and is well documented by immediate measurable changes in brain chemistry and physiology” and “the second complaint is of a persistent loss of personal memories…They do not recall the names of their children, family holidays, or personal events….Their complaints cast a public shadow on ECT practice.”

The Procedure

Electroshock is a psychiatric procedure that involves the production of a grand mal convulsion, similar to an epileptic seizure, by passing from 70 to upwards of 600 volts of electric current through the brain for one-half second to four seconds. Before application, ECT subjects are typically given anesthetic, tranquilizing and muscle-paralyzing drugs to reduce fear, pain, and the risk (from violent muscle spasms) of fractured bones (particularly of the spine, a common occurrence in the early history of ECT before the introduction, in the mid-1950s, of the muscle-paralyzing drug succinylcholine [Anectine]). The ECT-induced convulsion usually lasts from thirty to sixty seconds and may immediately produce disorienting, painful, and even life-threatening complications, such as apnea (temporary suspension of breathing) and cardiac arrest. The convulsion is followed by a period of unconsciousness of several minutes’ duration. Electroshock is usually administered in hospitals because they are equipped to handle emergency situations that often develop during or soon after an ECT session.

Brain Damage

The brain naturally operates in millivolts of electricity, and ECT administers on average between 150 and 400 volts of electricity to the brain, a force sufficient to induce a grand mal seizure, rupture the protective blood-brain barrier and incite glutamate toxicity (glutamate is a powerful neurotransmitter released by nerve cells in the brain and is responsible for sending signals between nerve cells. In glutamate toxicity there is too much glutamate that leads to over-excitation of the receiving nerve cell, which can cause cell damage and/or death). It is prima-facie, common sense obvious fact that ECT causes brain damage. After all, the rest of medicine, as well as the building trades, do their best to prevent people from being hurt or killed by electrical shock. People with epilepsy are given anticonvulsant drugs to prevent seizures because they are known to damage the brain. The Electroshock Quotationary, a collection of quotations, excerpts, and essays about the history and nature of electroshock, by shock survivor Leonard Roy Frank, includes the testimony of Peter Sterling, a University of Pennsylvania neuroscience professor, describing the nature of ECT-caused brain damage, dated May 31, 2001, to the New York Assembly Standing Committee on Mental Health at a public hearing on ECT.

Sterling affirms the obvious: that massive amounts of electricity directly into the brain cause profound damage.

Lack of Efficacy

Not only does electroshock directly violate the Hippocratic oath to do no harm, the practice has never been proven effective. There are no lasting beneficial effects of electroshock; sham-electroshock (anesthesia but no electroshock) has the same short-term outcomes as electroshock (Ross, 2006). Even leading shock researcher and advocate Harold Sackeim now provides a proof. In an article from 2001, he and his colleagues conclude, “Our study indicates that without active treatment, virtually all remitted patients relapse within 6 months of stopping ECT.” (Italics mine)

The FDA

The battle against electroshock has been ongoing since its advent. The two recent chronicles by electroshock survivor activist leaders, Leonard Roy Frank (The Electroshock Quotationary) and Linda Andre (Doctors of Deception), tell the story best. Just now, the fight has centered on the FDA review of the “efficacy and safety” of ECT machines.

Many activists, including myself, have submitted testimony urging the FDA NOT to reclassify these devices from Class III (high risk) to Class II (low risk). I have worked with scores of electroshock survivors, and I can tell you the damage is consistent and terrible. I can also tell you as a psychologist that there are methods so much gentler, safer and more effective to help people with depression.

A Repackaged Product

The reason for electroshock’s endurance and resurgence is best described by Linda Andre, shock survivor and leader of the Committee for Truth in Psychiatry, in her masterful new work, Doctors of Deception: What They Don’t Want You to Know About Shock Treatment—it is simply the triumph of public relations over science. A concerted PR campaign has allowed electroshock to continue despite clear scientific evidence of its dismal and tragic record on safety and efficacy.

The industry repackaged the product to keep it selling. They touted a “newer and safer ECT,” bragging about improved equipment and the introduction of anesthesia and muscle paralysants, which actually came on the market in the 1950s. While the muscle paralysants greatly reduced the risk of broken bones from unrestrained convulsions, there was no lessening of permanent damage to the brain caused by the electroshocks. The drugs made the procedure appear much more benign because they suppressed the body’s natural, violent reaction to a grand mal convulsion. However, as Doug Cameron (1994) and other researchers have shown, the new machines, because they are more powerful than ever are capable of releasing greater amounts of electricity into the brain thus causing more damage than the older devices.

With the newer technique modifications there is also an added risk. The drugs used to prevent bone complications raise the seizure threshold so that more electrical current is required to induce the convulsion, which in turn increases brain damage. Moreover, whereas ECT specialists formerly tried to induce seizures with minimal current, they commonly use suprathreshold amounts in the belief that they are more effective. Again, the more current, the more brain damage. Proponents, and the public, have missed the point that the supposed “effectiveness” of ECT is in direct ratio to the amount of brain damage it causes.

In addition to the propaganda effect and the financial incentives, there is a less well-considered reason for ECT’s popularity among psychiatrists. Although electroshock is often described as psychiatry’s “treatment of last resort,” it is actually psychiatry’s “treatment of next resort.” Next resort after psychiatric drugs, which are the main “treatment”—a treatment whose lack of effectiveness and lack of safety are well documented. Like ECT, these drugs can damage and disable the brain. Like ECT, they can cause a fully justified resentment that goes with the experience of having been betrayed by one’s supposed helpers.

Activist and electroshock survivor Leonard Roy Frank’s recent letter to the FDA in regards to their review of ECT devices is one of the best. I end this blog article with his conclusion:

As a destroyer of memories and thoughts, electroshock is a direct, violent assault on these hallmarks of American liberty: freedom of conscience, freedom of belief, freedom of thought, freedom of religion, freedom of speech, freedom from assault, and freedom from cruel and unusual punishment. Tens of thousands of people every year in the United States are deceived or coerced into undergoing electroshock. The FDA should do everything in its power to discourage the use of electroshock by:

  • keeping ECT’s Class III, high-risk rating;
  • insisting that electroshock psychiatrists, manufacturers of ECT devices, and executives and administrators in hospitals where ECT is administered, substantiate with scientific proof their claims that the procedure is “safe and effective”;
  • and calling upon the Congress and the Department of Justice to investigate the fraudulent and coercive use of this cruel and inhuman procedure.

Despite the evidence of grievous harm and failure to help, electroshock’s proponents rave on; as an example, an electroshock psychiatrist told Washington Post reporter Sandra Boodman in 1996, that, “ECT is one of God’s gifts to mankind. There is nothing like it, nothing equal to it in efficacy or safety in all of psychiatry.”

Given that ECT causes brain damage, memory loss, and other serious cognitive impairment, electroshock serves to cover up and impede any potential malpractice or personal injury litigation. It generally takes years for a shock survivor to recover enough to figure out what has happened to them, and most states have a statute of limitations (usually one or two years) on medical malpractice and personal injury suits. As a result, electroshock survivors are effectively prevented from pursuing litigation against those who harmed them, making electroshock psychiatrists almost malpractice-proof.


John Breeding, Ph.D. has been a counseling psychologist in Austin, Texas for 25 years.
He is an outspoken critic of electroshock treatment and has testified against its use before legislative bodies on numerous occasions. Dr. Breeding is also the director of Texans For Safe Education, a citizens group dedicated to challenging the ever-increasing role of psychiatric drugs in schools. He is the author of numerous articles and four books including:
The Wildest Colts Make the Best Horses and True Nature and Great Misunderstandings.

For more information on the damage caused by ECT, visit www.endofshock.com

References

Ayd Jr., F.T. (November-December 1963). “Guest editorial: Ugo Cerletti, M.D. (1877-1963),” Psychosomatics, Vol. 4, pp. A-6 – A-7.

Boodman, S.G. (September 24, 1996). “Shock therapy: It’s back,” Washington Post (Health Section), pp. 14-20.

Frank, Leonard Roy, The Electroshock Quotationary, June 2006, www.endofshock.com/102C_ECT.PDF.

Andre, Linda, Doctors of Deception, www.doctorsofdeception.com.

Kalinowsky, L.B. (1988). Quoted in R. Abrams, “Interview with Lothar Kalinowsky, M.D.,” Convulsive Therapy, Vol. 4.

Ross, C.A. (Spring 2006). “The sham ECT literature: Implications for consent to ECT,” Ethical Human Psychology and Psychiatry, Vol. 8.

Sackeim, H.A. et al. (March 14, 2001). “Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy,” Journal of the American Medical Association.

Sackeim, H.A. (2001). “Memory loss: From polarization to reconciliation,” Journal of ECT, vol. 17, no. 3, p. 229. Sackeim, H.A., Prudic, J. et al. (January 2007). “The cognitive effects of electroconvulsive therapy in community settings,” Neuropsychopharmacology, Vol. 32, pp. 244-254.

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The DEA classifies ADHD drugs with cocaine/opium/morphine—all highly addictive. Teen abuse of ADHD drugs skyrockets.

Friday, January 22nd, 2010

NaturalNews
By David Gutierrez
January 21, 2010

Inquiries to poison control centers about teenage abuse of drugs for attention deficit hyperactivity disorder (ADHD) increased by 76 percent over the last eight years, indicating a surge in rates of the abuse itself, according to a study conducted by researchers from the Cincinnati Children’s Hospital Memorial Center and published in the journal Pediatrics.

“It’s more bad news on an entrenched problem,” said Steve Pasierb, head of The Partnership for a Drug-Free America, who was not involved in the study.

The researchers reviewed data collected by the American Association of Poison Control Centers between 1998 and 2005. They found that the number of calls by parents, emergency room doctors and others about teenagers abusing ADHD drugs increased from 330 per year in 1998 to 581 per year in 2005, far outpacing the rate of increase in calls about other forms of teenage substance abuse. The majority of teenagers involved in the calls ended up being treated in emergency rooms, and 42 percent suffered moderate or severe side effects. Four of the teenagers died.

Far more teenagers are probably experiencing side effects, the researchers noted, since most cases of abuse don’t end in calls to poison control.

During the time period covered by the study, prescriptions for ADHD drugs rose 86 percent in children between the ages of 10 and 19, from roughly four million to almost eight million.

Read entire article:  http://www.naturalnews.com/027988_drug_abuse_ADHD.html

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Senator Grassley’s investigation of pharma funded psychiatrists leads to National Institute of Mental Health probe

Thursday, January 21st, 2010

Science Insider
By Jocelyn Kaiser
January 20, 2010

As part of his ongoing investigation of conflicts of interest in biomedicine, Senator Charles Grassley (R–IA) now wants to comb through the e-mails of Thomas Insel, director of the National Institute of Mental Health (NIMH). Grassley points out in a letter today to NIH Director Francis Collins that his 2-year probe has found five psychiatrists who failed to report drug company income or had other conflict issues—all of them researchers with funding from NIMH. “I wonder if there is something in particular about this institute that leads to so many funding problems,” the letter says. It asks for Insel’s e-mails and his calendar since 2 May; his phone records for 2009 and 2010; and NIMH staff members’ e-mails and communications regarding Senate investigations or conflicts of interest back to June 2008. Grassley wants all of this by 3 February.

Read entire article:  http://blogs.sciencemag.org/scienceinsider/2010/01/grassley-goes-f.html

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Army psychiatrists who supervised psychiatrist/Fort Hood shooter Nidal Hasan face charges for failing to take action

Thursday, January 21st, 2010

NPR
By Daniel Zwerdling
January 21, 2010

The Army has told some of the psychiatrists who supervised Fort Hood shooting suspect Nidal Hasan that it’s investigating them — and they could face punishments from letters of reprimand to court martial.

The Army said it’s going to decide if the doctors at Walter Reed “failed to take appropriate action” against Hasan and were “derelict” in their duties.

Evidence shows a lot of doctors were worried about Hasan — some for years. Evidence also shows that only one supervisor, Scott Moran, actively tried to kick Hasan out of the psychiatry program. Now sources involved in the investigation say Moran is one of the officers who’s in big trouble. Moran wouldn’t comment, but the sources say the supervisors under investigation are fairly low level officers like Moran, who is a major.

“They’re attacking the wrong target,” says Gary Myers, a lawyer who’s representing Col. Charles Engel, another psychiatrist whom Myers says is under investigation.

Engel was Hasan’s main supervisor in the fellowship program at the military’s medical school, the Uniformed Services University of the Health Sciences. Myers says the Army is trying to find scapegoats and that everybody knows officials in the nation’s intelligence agencies bear at least some responsibility for what happened at Fort Hood.

Read entire article:  http://www.npr.org/templates/story/story.php?storyId=122778372

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